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Holland America to Panama Canal

A Holland America cruise to the Panama Canal allows guests to walk where Mayan’s walked, explore Costa Rica’s lush rainforests, stretch out on the beach at Holland America Line’s private island, Half Moon Cay, and so much more. And of course, no trip through the Caribbean or along the coast of Central America is complete without a passage through the man-made wonder of the Panama Canal. A Holland America Panama Canal cruise features all of the amenities and entertainment that Holland America Cruises guests love. Holland America cruises to the Panama Canal offer a variety of 10- to 28-day itineraries for the perfect Panama Canal cruise vacation.

Showing 1-18 of 18 results
15-night panama canal cruise
Inside From
$2,049
Holland America – Zuiderdam
4.3157 Reviews
Departs Jan 30, 2027 from San Diego, California
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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21-night panama canal cruise
Inside From
$2,969
2% Off
Holland America – Eurodam
4.3283 Reviews
Departs Oct 02, 2027 from Seattle, Washington
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
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14-night panama canal cruise
Inside From
$2,559
3% Off
Holland America – Zaandam
4.5133 Reviews
Departs Jan 16, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
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16-night panama canal cruise
Inside From
$2,769
3% Off
Holland America – Eurodam
4.3283 Reviews
Departs Apr 01, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
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15-night panama canal cruise
Inside From
$2,624
6% Off
Holland America – Oosterdam
4.2213 Reviews
Departs Apr 07, 2028 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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14-night panama canal cruise
Inside From
$1,899
Holland America – Zuiderdam
4.3157 Reviews
Departs Jan 02, 2027 from Miami, Florida
Up to 2 deals including an Avoya Exclusive
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14-night panama canal cruise
Inside From
$1,399
Holland America – Zaandam
4.5133 Reviews
Departs Mar 14, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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14-night panama canal cruise
Inside From
$2,034
Holland America – Eurodam
4.3283 Reviews
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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21-night panama canal cruise
Inside From
$2,349
Holland America – Eurodam
4.3283 Reviews
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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17-night panama canal cruise
Inside From
$1,974
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Apr 11, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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20-night panama canal cruise
Inside From
$2,254
Holland America – Eurodam
4.3283 Reviews
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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21-night panama canal cruise
Inside From
$2,249
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Apr 11, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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20-night panama canal cruise
Inside From
$2,949
Holland America – Eurodam
4.3283 Reviews
Departs Oct 03, 2027 from Vancouver, BC, Canada
Up to 3 deals including an Avoya Exclusive
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16-night panama canal cruise
Inside From
$2,769
Holland America – Eurodam
4.3283 Reviews
Departs Oct 07, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
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15-night panama canal cruise
Inside From
$2,674
Holland America – Zaandam
4.5133 Reviews
Departs Dec 18, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
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22-night panama canal cruise
Inside From
$3,409
Holland America – Eurodam
4.3283 Reviews
Departs Apr 01, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
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21-night panama canal cruise
Inside From
$3,434
Holland America – Oosterdam
4.2213 Reviews
Departs Apr 07, 2028 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
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15-night panama canal cruise
Balcony From
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Holland America – Zaandam
4.5133 Reviews
Departs Dec 19, 2026 from San Diego, California
Up to 2 deals including an Avoya Exclusive
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