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Best Panama Canal Cruises

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16-night panama canal cruise
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Princess Cruises – Island Princess
4.2 (157)
Departs Apr 19, 2027 from Fort Lauderdale, Florida
Up to 6 deals including an Avoya Exclusive
16-night panama canal cruise
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Princess Cruises – Sapphire Princess
4.3 (86)
Departs Nov 06, 2026 from Fort Lauderdale, Florida
Up to 1 deal
12-night panama canal cruise
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Princess Cruises – Caribbean Princess
4.1 (256)
Departs Nov 11, 2026 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
16-night panama canal cruise
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Princess Cruises – Island Princess
4.2 (157)
Departs Jan 29, 2027 from San Diego, California
Up to 6 deals including an Avoya Exclusive
16-night panama canal cruise
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Princess Cruises – Crown Princess
4.3 (211)
Departs Apr 04, 2027 from Fort Lauderdale, Florida
Up to 6 deals including an Avoya Exclusive
Secret Rate
7-night panama canal cruise
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Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 12, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
16-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Dec 12, 2026 from Oranjestad, Aruba
Up to 2 deals including an Avoya Exclusive
8-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Dec 12, 2026 from Oranjestad, Aruba
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 19, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 26, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 05, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 12, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 19, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Wind Star
4.6 (89)
Departs Jan 24, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 26, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
29-night panama canal cruise
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Windstar Cruises – Wind Star
4.6 (89)
Departs Jan 31, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Legend
4.5 (86)
Departs Feb 09, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Dec 06, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Dec 13, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Dec 20, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Dec 27, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Jan 03, 2028 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Jan 10, 2028 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Jan 17, 2028 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
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Windstar Cruises – Star Pride
4.5 (95)
Departs Jan 24, 2028 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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