7-night mexico cruise
Inside From
$749
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Nov 22, 2026 from San Diego, California
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Best Cruises out of San Diego, CA
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Up to 4 deals including Avoya Exclusives
4-night mexico cruise
Inside From
$360
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 11, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$556
10% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 18, 2026 from San Diego, California
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4-night mexico cruise
Inside From
$311
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Nov 29, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$1,091
3% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 27, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$505
9% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Jan 28, 2027 from San Diego, California
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4-night mexico cruise
Inside From
$342
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Feb 21, 2027 from San Diego, California
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7-night mexico cruise
Inside From
$649
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Mar 28, 2027 from San Diego, California
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7-night mexico cruise
Inside From
$591
9% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Apr 25, 2027 from San Diego, California
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2-night mexico cruise
Inside From
$274
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 02, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$499
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 04, 2026 from San Diego, California
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3-night mexico cruise
Inside From
$324
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 15, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$500
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Oct 25, 2026 from San Diego, California
Up to 3 deals including an Avoya ExclusiveView Expanded Details
7-night mexico cruise
Inside From
$499
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Nov 01, 2026 from San Diego, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
7-night mexico cruise
Inside From
$519
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Nov 08, 2026 from San Diego, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
7-night mexico cruise
Inside From
$529
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Nov 15, 2026 from San Diego, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
3-night mexico cruise
Inside From
$284
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 03, 2026 from San Diego, California
Up to 5 deals including Avoya ExclusivesView Expanded Details
4-night mexico cruise
Inside From
$330
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 06, 2026 from San Diego, California
Up to 5 deals including Avoya ExclusivesView Expanded Details
3-night mexico cruise
Inside From
$303
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 10, 2026 from San Diego, California
Up to 5 deals including Avoya ExclusivesAvoya Exclusive Rate
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7-night mexico cruise
Inside From
$483
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 13, 2026 from San Diego, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
7-night mexico cruise
Inside From
$660
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Dec 20, 2026 from San Diego, California
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7-night mexico cruise
Inside From
$526
5% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Jan 03, 2027 from San Diego, California
Up to 4 deals including Avoya ExclusivesAvoya Exclusive Rate
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4-night mexico cruise
Inside From
$310
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Jan 10, 2027 from San Diego, California
Up to 5 deals including Avoya ExclusivesView Expanded Details
3-night mexico cruise
Inside From
$299
2% Off
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Jan 14, 2027 from San Diego, California
Up to 5 deals including Avoya ExclusivesAvoya Exclusive Rate
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4-night mexico cruise
Inside From
$333
Royal Caribbean – Serenade of the Seas
4.5214 Reviews
Departs Jan 17, 2027 from San Diego, California
Up to 5 deals including Avoya ExclusivesView Expanded Details
Cruises from San Diego, CA
Cruises from San Diego are a wonderful option for guests departing from the West Coast. Offering varied itineraries for cruisers both regionally and out-of-state, visitors sailings from this North America Departure Port are also convenient – as before or after your San Diego cruise, you can explore the city’s unique attractions. Popular destinations that you can visit on cruises from San Diego include Mexico, Hawaii, and more!
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