16-night hawaii cruise
Inside From
$1,379
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jan 11, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveAvoya Exclusive Rate
View Expanded Details
Best Cruises out of San Francisco, CA
Showing 1-25 of 87 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Up to 5 deals including an Avoya Exclusive
16-night hawaii cruise
Inside From
$1,379
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Mar 16, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveAvoya Exclusive Rate
View Expanded Details
16-night hawaii cruise
Inside From
$1,199
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 01, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveAvoya Exclusive Rate
View Expanded Details
7-night usa cruise
Inside From
$839
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 24, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveAvoya Exclusive Rate
View Expanded Details
7-night usa cruise
Inside From
$900
14% Off
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Sep 18, 2027 from San Francisco, California
Up to 6 deals including Avoya ExclusivesAvoya Exclusive Rate
View Expanded Details
16-night hawaii cruise
Inside From
$1,624
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Feb 16, 2028 from San Francisco, California
Up to 7 deals including Avoya ExclusivesAvoya Exclusive Rate
View Expanded Details
7-night usa cruise
Inside From
$900
10% Off
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Mar 19, 2028 from San Francisco, California
Up to 7 deals including Avoya ExclusivesAvoya Exclusive Rate
View Expanded Details
5-night usa cruise
Oceanview From
$789
10% Off
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 25, 2028 from San Francisco, California
Up to 7 deals including Avoya ExclusivesAvoya Exclusive Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,124
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs May 01, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,124
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs May 11, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,294
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs May 21, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,184
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs May 31, 2027 from San Francisco, California
Up to 4 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,124
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jun 10, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,224
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jun 20, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,164
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jun 30, 2027 from San Francisco, California
Up to 4 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,184
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jul 10, 2027 from San Francisco, California
Up to 6 deals including Avoya ExclusivesSecret Rate
Avoya Exclusive Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,424
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jul 20, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$999
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Jul 30, 2027 from San Francisco, California
Up to 6 deals including Avoya ExclusivesSecret Rate
Avoya Exclusive Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,074
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Aug 19, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,224
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Aug 29, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
10-night alaska cruise
Inside From
$1,424
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Sep 08, 2027 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveSecret Rate
View Expanded Details
17-night australia cruise
Suite From
$18,299
58% Off List
Regent Cruises – Seven Seas Splendor
4.331 Reviews
Departs Jan 06, 2028 from San Francisco, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
7-night usa and canada cruise
Suite From
$7,699
62% Off List
Regent Cruises – Seven Seas Splendor
4.331 Reviews
Departs May 17, 2028 from San Francisco, California
Up to 4 deals including Avoya ExclusivesView Expanded Details
16-night hawaii cruise
Inside From
$1,209
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Nov 08, 2026 from San Francisco, California
Up to 6 deals including Avoya ExclusivesView Expanded Details
16-night hawaii cruise
Inside From
$1,182
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Nov 29, 2026 from San Francisco, California
Up to 5 deals including an Avoya ExclusiveAvoya Exclusive Rate
View Expanded Details
Cruises from San Francisco, CA
Cruises from San Francisco are convenient and will take you to a variety of top destinations that travelers love. San Francisco is a bustling and swanky city, brimming with history and a unique culture. This is best exemplified in various areas surrounding the San Francisco port-of-call including landmarks such as the Golden Gate Bridge, attractions like Fisherman’s Wharf, and neighborhoods like Chinatown. Whether you want to sail North to Alaska, along the West Coast, or South to Mexico, there are an array of San Francisco cruises to enjoy.
AmaWaterways American Cruise Lines Atlas Ocean Voyages Aurora Expeditions Avalon Waterways Azamara Cruises Carnival Cruises Celebrity Cruises Celebrity River Cruises Celestyal Cruises Crystal Cruises Cunard Disney Cruises Explora Journeys Holland America HX Cruises Margaritaville at Sea MSC Cruises Norwegian Cruise Line Oceania Cruises Paul Gauguin Cruises Ponant Explorations Princess Cruises Regent Cruises Riviera Travel Royal Caribbean Scenic River Cruises Seabourn Silversea Swan Hellenic Tauck River Cruises Viking Ocean Cruises Viking River Cruises Virgin Voyages Windstar Cruises
Don't Miss the Latest Deals!
- Save favorite vacations & searches
- Early access to promotions
- Exclusive deals, discounts & prices
- Plus more!
Talk to a Vacation Planner
Call at 1-888-447-8459
1-888-447-8459
or click here to submit a form and we will connect you with a Personal Travel Advisor that specializes in the type of travel you are interested in. 
Why Choose Avoya?
From powerful online search, to specialized vacation planning services, and exclusive deals and extras - discover what makes Avoya Travel a different, better type of travel company.