Cruises from San Francisco are convenient and will take you to a variety of top destinations that travelers love. San Francisco is a bustling and swanky city, brimming with history and a unique culture. This is best exemplified in various areas surrounding the San Francisco port-of-call including landmarks such as the Golden Gate Bridge, attractions like Fisherman’s Wharf, and neighborhoods like Chinatown. Whether you want to sail North to Alaska, along the West Coast, or South to Mexico, there are an array of San Francisco cruises to enjoy.