16-night hawaii cruise
Inside From
$1,984
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Dec 29, 2028 from San Francisco, California
Up to 4 deals including an Avoya ExclusiveView Expanded Details
Best Cruises out of San Francisco, CA
Showing 51-75 of 120 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Up to 4 deals including an Avoya Exclusive
7-night usa cruise
Inside From
$1,225
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 01, 2029 from San Francisco, California
View Expanded Details
7-night usa cruise
Inside From
$1,225
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 08, 2029 from San Francisco, California
View Expanded Details
6-night usa cruise
Inside From
$875
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Apr 15, 2029 from San Francisco, California
View Expanded Details
48-night grand voyage cruise
Oceanview From
$17,149
Azamara Cruises – Azamara Quest
4.6127 Reviews
Departs Jan 05, 2027 from San Francisco, California
Up to 1 deal including an Avoya ExclusiveView Expanded Details
87-night grand voyage cruise
Oceanview From
$30,519
Azamara Cruises – Azamara Quest
4.6127 Reviews
Departs Jan 05, 2027 from San Francisco, California
Up to 1 deal including an Avoya ExclusiveView Expanded Details
16-night hawaii cruise
Inside From
$1,784
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Oct 19, 2028 from San Francisco, California
View Expanded Details
7-night usa cruise
Inside From
$975
Princess Cruises – Ruby Princess
4.2224 Reviews
Departs Nov 04, 2028 from San Francisco, California
View Expanded Details
5-night mexico cruise
Inside From
$787
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Apr 28, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,008
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs May 03, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$505
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs May 13, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$971
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs May 17, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$520
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs May 27, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,076
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs May 31, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$590
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jun 10, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,296
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jun 14, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$605
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jun 24, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,227
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jun 28, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$617
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jul 08, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,338
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jul 12, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$612
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jul 22, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,258
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Jul 26, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$587
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Aug 05, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
10-night alaska cruise
Inside From
$1,068
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Aug 09, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
4-night mexico cruise
Inside From
$522
Carnival Cruises – Carnival Luminosa
5.01 Reviews
Departs Aug 19, 2027 from San Francisco, California
Up to 6 deals
View Expanded Details
Cruises from San Francisco, CA
Cruises from San Francisco are convenient and will take you to a variety of top destinations that travelers love. San Francisco is a bustling and swanky city, brimming with history and a unique culture. This is best exemplified in various areas surrounding the San Francisco port-of-call including landmarks such as the Golden Gate Bridge, attractions like Fisherman’s Wharf, and neighborhoods like Chinatown. Whether you want to sail North to Alaska, along the West Coast, or South to Mexico, there are an array of San Francisco cruises to enjoy.
AmaWaterways American Cruise Lines Atlas Ocean Voyages Aurora Expeditions Avalon Waterways Azamara Cruises Carnival Cruises Celebrity Cruises Celebrity River Cruises Celestyal Cruises Crystal Cruises Cunard Disney Cruises Explora Journeys Holland America HX Cruises Margaritaville at Sea MSC Cruises Norwegian Cruise Line Oceania Cruises Paul Gauguin Cruises Ponant Explorations Princess Cruises Regent Cruises Riviera Travel Royal Caribbean Scenic River Cruises Seabourn Silversea Swan Hellenic Tauck River Cruises Viking Ocean Cruises Viking River Cruises Virgin Voyages Windstar Cruises
Don't Miss the Latest Deals!
- Save favorite vacations & searches
- Early access to promotions
- Exclusive deals, discounts & prices
- Plus more!
Talk to a Vacation Planner
Call at 1-888-447-8459
1-888-447-8459
or click here to submit a form and we will connect you with a Personal Travel Advisor that specializes in the type of travel you are interested in. 
Why Choose Avoya?
From powerful online search, to specialized vacation planning services, and exclusive deals and extras - discover what makes Avoya Travel a different, better type of travel company.