Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best Panama Canal Cruises

Showing 201-209 of 209 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
16-night panama canal cruise
$1,069
Carnival Cruises – Carnival Spirit
4.4 (36)
Departs Apr 12, 2026 from Mobile, Alabama
Up to 1 deal
10-night panama canal cruise
$1,925
75% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Apr 14, 2026 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
10-night panama canal cruise
$3,599
50% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Apr 24, 2026 from Panama City (Fuerte Amador), Panama
Up to 5 deals including an Avoya Exclusive
20-night panama canal cruise
Call Us
Princess Cruises – Star Princess
Departs Apr 13, 2026 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
Secret Rate
19-night panama canal cruise
Call Us
Seabourn – Seabourn Quest
4.6 (43)
Departs Apr 07, 2026 from Long Beach, California
Up to 3 deals including Avoya Exclusives
10-night panama canal cruise
Call Us
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 09, 2027 from Miami, Florida
11-night panama canal cruise
Call Us
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 19, 2027 from Miami, Florida
11-night panama canal cruise
Call Us
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 30, 2027 from Miami, Florida
10-night panama canal cruise
Call Us
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Dec 11, 2027 from Miami, Florida
  1. Prev
  2. 1…
  3. 5
  4. 6
  5. 7
  6. 8
  7. 9

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo