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Best South America Cruises

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96-night south america cruise + tour
$83,998
Seabourn – Seabourn Venture
5.0 (2)
Departs Mar 11, 2028 from Buenos Aires, Argentina
Up to 1 deal
48-night south america cruise + tour
$35,098
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Mar 25, 2028 from Buenos Aires, Argentina
Up to 1 deal
16-night south america cruise
$10,999
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Oct 02, 2028 from Oranjestad, Aruba
Up to 1 deal
38-night south america cruise + tour
$36,898
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Oct 02, 2028 from Oranjestad, Aruba
Up to 1 deal
16-night south america cruise
$10,999
Seabourn – Seabourn Venture
5.0 (2)
Departs Oct 10, 2028 from Bridgetown, Barbados
Up to 1 deal
41-night south america cruise + tour
$34,198
Seabourn – Seabourn Venture
5.0 (2)
Departs Oct 10, 2028 from Bridgetown, Barbados
Up to 1 deal
22-night south america cruise + tour
$29,998
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Oct 18, 2028 from Santiago (Valparaiso), Chile
Up to 1 deal
25-night south america cruise + tour
$26,998
Seabourn – Seabourn Venture
5.0 (2)
Departs Oct 26, 2028 from Rio de Janeiro, Brazil
Up to 1 deal
21-night south america cruise + tour
$29,998
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Nov 08, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$14,998
Seabourn – Seabourn Venture
5.0 (2)
Departs Nov 19, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$15,498
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Nov 28, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$15,498
Seabourn – Seabourn Venture
5.0 (2)
Departs Nov 29, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$16,998
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Dec 08, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$16,998
Seabourn – Seabourn Venture
5.0 (2)
Departs Dec 09, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$17,598
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Dec 18, 2028 from Buenos Aires, Argentina
Up to 1 deal
21-night south america cruise + tour
$32,998
Seabourn – Seabourn Venture
5.0 (2)
Departs Dec 19, 2028 from Buenos Aires, Argentina
Up to 1 deal
11-night south america cruise + tour
$17,598
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Dec 28, 2028 from Buenos Aires, Argentina
Up to 1 deal
29-night south america cruise
$18,998
Seabourn – Seabourn Quest
4.6 (43)
Departs Jan 07, 2028 from Miami, Florida
Up to 1 deal
7-night south america cruise
$3,948
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jul 18, 2026 from Cartagena, Colombia
Up to 5 deals including Avoya Exclusives
7-night south america cruise
$4,748
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Aug 22, 2026 from Barranquilla, Colombia
Up to 4 deals including Avoya Exclusives
7-night south america cruise
$4,098
AmaWaterways – AmaMelodia
Departs Sep 16, 2026 from Barranquilla, Colombia
Up to 3 deals including an Avoya Exclusive
4-night south america cruise
$744
MSC Cruises – MSC Divina
3.8 (92)
Departs Nov 12, 2026 from Salvador, Brazil
Up to 2 deals
7-night south america cruise
$4,098
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Nov 14, 2026 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
$4,348
AmaWaterways – AmaMelodia
Departs Nov 18, 2026 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
$4,698
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Nov 28, 2026 from Barranquilla, Colombia
Up to 1 deal

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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