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Best South America Cruises

Showing 126-150 of 440 results
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21-night south america cruise
$17,999
60% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Feb 26, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
16-night south america cruise
$2,099
Holland America – Oosterdam
4.2 (212)
Departs Nov 18, 2026 from Fort Lauderdale, Florida
Up to 3 deals including Avoya Exclusives
27-night south america cruise
$4,684
Holland America – Volendam
4.3 (73)
Departs Nov 25, 2026 from Fort Lauderdale, Florida
Up to 3 deals including Avoya Exclusives
15-night south america cruise
$2,499
Holland America – Oosterdam
4.2 (212)
Departs Mar 09, 2027 from Buenos Aires, Argentina
Up to 3 deals including Avoya Exclusives
16-night south america cruise
$2,299
Holland America – Oosterdam
4.2 (212)
Departs Mar 24, 2027 from San Antonio, Chile
Up to 3 deals including Avoya Exclusives
16-night south america cruise
$3,739
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Dec 17, 2027 from Buenos Aires, Argentina
Up to 1 deal
15-night south america cruise
$2,929
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Jan 02, 2028 from San Antonio, Chile
Up to 1 deal
14-night south america cruise
$8,000
Silversea – Silver Shadow
4.5 (40)
Departs Jan 15, 2028 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
12-night south america cruise
$8,600
Silversea – Silver Ray
5.0 (3)
Departs Jan 15, 2028 from Miami, Florida
Up to 1 deal including an Avoya Exclusive
15-night south america cruise
$2,959
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Jan 17, 2028 from Buenos Aires, Argentina
Up to 1 deal
21-night south america cruise
$16,200
Silversea – Silver Ray
5.0 (3)
Departs Jan 27, 2028 from Lima (Callao), Peru
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$13,800
Silversea – Silver Shadow
4.5 (40)
Departs Jan 29, 2028 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,889
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 01, 2028 from San Antonio, Chile
Up to 1 deal
12-night south america cruise
$12,900
Silversea – Silver Shadow
4.5 (40)
Departs Feb 15, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,959
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 16, 2028 from Buenos Aires, Argentina
Up to 1 deal
12-night south america cruise
$11,400
Silversea – Silver Ray
5.0 (3)
Departs Feb 17, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
19-night south america cruise
$10,500
Silversea – Silver Shadow
4.5 (40)
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya Exclusive
20-night south america cruise
$15,500
Silversea – Silver Ray
5.0 (3)
Departs Feb 29, 2028 from Rio de Janeiro, Brazil
Up to 1 deal including an Avoya Exclusive
15-night south america cruise
$3,239
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Mar 02, 2028 from San Antonio, Chile
Up to 1 deal
31-night south america cruise
$4,379
Holland America – Oosterdam
4.2 (212)
Departs Nov 18, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
30-night south america cruise
$4,699
Holland America – Volendam
4.3 (73)
Departs Nov 22, 2026 from New York City, New York
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,599
Holland America – Oosterdam
4.2 (212)
Departs Dec 04, 2026 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
22-night south america cruise
$5,099
Holland America – Oosterdam
4.2 (212)
Departs Dec 19, 2026 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
41-night south america cruise
$10,284
Holland America – Zaandam
4.5 (132)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Up to 1 deal
70-night south america cruise
$15,614
Holland America – Zaandam
4.5 (132)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Up to 1 deal

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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