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Best Panama Canal Cruises

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16-night panama canal cruise
$1,084
Carnival Cruises – Carnival Spirit
4.4 (36)
Departs Oct 08, 2026 from Seattle, Washington
Up to 6 deals including an Avoya Exclusive
26-night panama canal cruise
$2,899
Cunard – Queen Victoria
4.4 (19)
Departs Jan 10, 2027 from Southampton, United Kingdom
Up to 3 deals including Avoya Exclusives
17-night panama canal cruise
$3,349
Cunard – Queen Victoria
4.4 (19)
Departs Jan 19, 2027 from New York City, New York
Up to 3 deals including Avoya Exclusives
16-night panama canal cruise
$1,074
Carnival Cruises – Carnival Spirit
4.4 (36)
Departs Mar 29, 2027 from Mobile, Alabama
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$1,279
Carnival Cruises – Carnival Legend
4.3 (51)
Departs Apr 04, 2027 from Tampa, Florida
Up to 2 deals including an Avoya Exclusive
19-night panama canal cruise
$7,649
Seabourn – Seabourn Quest
4.6 (43)
Departs May 11, 2027 from Long Beach, California
Up to 2 deals including an Avoya Exclusive
14-night panama canal cruise
$1,249
Carnival Cruises – Carnival Valor
4.5 (71)
Departs Sep 26, 2027 from Mobile, Alabama
Up to 2 deals including an Avoya Exclusive
29-night panama canal cruise
$6,329
Cunard – Queen Anne
5.0 (1)
Departs Jan 09, 2028 from Hamburg, Germany
Up to 1 deal including an Avoya Exclusive
27-night panama canal cruise
$5,389
Cunard – Queen Anne
5.0 (1)
Departs Jan 11, 2028 from Southampton, United Kingdom
Up to 1 deal including an Avoya Exclusive
14-night panama canal cruise
$3,129
Cunard – Queen Elizabeth
4.1 (35)
Departs Apr 13, 2028 from Los Angeles, California
Up to 1 deal including an Avoya Exclusive
16-night panama canal cruise
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Princess Cruises – Island Princess
4.2 (157)
Departs Feb 25, 2026 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
11-night panama canal cruise
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Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Mar 16, 2026 from Fort Lauderdale, Florida
Up to 6 deals including Avoya Exclusives
27-night panama canal cruise
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Princess Cruises – Grand Princess
4.3 (137)
Departs Apr 05, 2026 from San Juan, Puerto Rico
Up to 5 deals including an Avoya Exclusive
Secret Rate
15-night panama canal cruise
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Holland America – Zuiderdam
4.3 (156)
Departs Feb 27, 2026 from San Diego, California
Up to 3 deals including Avoya Exclusives
12-night panama canal cruise
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Norwegian Cruise Line – Norwegian Jade
4.2 (153)
Departs Feb 27, 2026 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
15-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Apr 05, 2026 from Fort Lauderdale, Florida
Up to 4 deals including Avoya Exclusives
20-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Apr 05, 2026 from Fort Lauderdale, Florida
Up to 4 deals including Avoya Exclusives
17-night panama canal cruise
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Holland America – Koningsdam
4.2 (239)
Departs Apr 10, 2026 from Fort Lauderdale, Florida
Up to 3 deals including Avoya Exclusives
26-night panama canal cruise
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Holland America – Zuiderdam
4.3 (156)
Departs Feb 27, 2026 from San Diego, California
Up to 2 deals including Avoya Exclusives
27-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
34-night panama canal cruise
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Holland America – Koningsdam
4.2 (239)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
29-night panama canal cruise
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Holland America – Koningsdam
4.2 (239)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
22-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
26-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
19-night panama canal cruise
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Holland America – Eurodam
4.3 (283)
Departs Apr 05, 2026 from Fort Lauderdale, Florida
Up to 3 deals including Avoya Exclusives

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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