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Best South America Cruises

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6-night south america cruise
$779
MSC Cruises – MSC Divina
3.8 (92)
Departs Mar 08, 2027 from CAMBORIU
7-night south america cruise
$1,016
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 09, 2027 from Salvador, Brazil
7-night south america cruise
$884
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 10, 2027 from MACEIO
3-night south america cruise
$259
MSC Cruises – MSC Divina
3.8 (92)
Departs Mar 11, 2027 from Buenos Aires, Argentina
3-night south america cruise
$423
56% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Mar 12, 2027 from Santos, Brazil
7-night south america cruise
$889
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 13, 2027 from Santos, Brazil
4-night south america cruise
$475
58% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Mar 15, 2027 from Santos, Brazil
8-night south america cruise
$1,241
50% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Mar 15, 2027 from Buenos Aires, Argentina
7-night south america cruise
$1,060
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 16, 2027 from Salvador, Brazil
7-night south america cruise
$1,060
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 17, 2027 from MACEIO
3-night south america cruise
$423
56% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Mar 19, 2027 from Santos, Brazil
7-night south america cruise
$889
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 20, 2027 from Santos, Brazil
4-night south america cruise
$475
58% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Mar 22, 2027 from Santos, Brazil
7-night south america cruise
$1,060
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 23, 2027 from Salvador, Brazil
8-night south america cruise
$1,076
50% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Mar 23, 2027 from Buenos Aires, Argentina
7-night south america cruise
$1,016
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 24, 2027 from MACEIO
7-night south america cruise
$1,018
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 27, 2027 from Santos, Brazil
3-night south america cruise
$423
56% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Mar 29, 2027 from Santos, Brazil
4-night south america cruise
$535
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 30, 2027 from Salvador, Brazil
3-night south america cruise
$408
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 31, 2027 from MACEIO
26-night south america cruise
$5,169
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
41-night south america cruise
$8,089
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
17-night south america cruise
$8,499
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Jan 07, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$8,499
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Jan 24, 2028 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$8,499
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Feb 10, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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