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Best South America Cruises

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13-night south america cruise
$10,995
Viking Ocean Cruises – Viking Octantis
4.7 (9)
Departs Mar 20, 2027 from Ushuaia, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$11,995
Viking Ocean Cruises – Viking Polaris
5.0 (1)
Departs Mar 22, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
19-night south america cruise
$11,995
Viking Ocean Cruises – Viking Octantis
4.7 (9)
Departs Apr 01, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
12-night south america cruise
$10,995
Viking Ocean Cruises – Viking Polaris
5.0 (1)
Departs Nov 01, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
12-night south america cruise
$11,495
Viking Ocean Cruises – Viking Octantis
4.7 (9)
Departs Nov 05, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$8,099
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Dec 04, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$8,299
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Dec 21, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
28-night south america cruise
$5,779
Holland America – Zuiderdam
4.3 (156)
Departs Jan 06, 2028 from Fort Lauderdale, Florida
Up to 2 deals including Avoya Exclusives
14-night south america cruise
$8,000
Silversea – Silver Shadow
4.5 (40)
Departs Jan 15, 2028 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
12-night south america cruise
$12,900
Silversea – Silver Shadow
4.5 (40)
Departs Feb 15, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
19-night south america cruise
$9,100
Silversea – Silver Shadow
4.5 (40)
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya Exclusive
8-night south america cruise
$1,626
50% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 25, 2026 from Buenos Aires, Argentina
8-night south america cruise
$2,617
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Feb 25, 2026 from Montevideo, Uruguay
Up to 1 deal
4-night south america cruise
$897
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 27, 2026 from Santos, Brazil
7-night south america cruise
$1,086
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 28, 2026 from Santos, Brazil
7-night south america cruise
$1,053
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Mar 01, 2026 from Santos, Brazil
Up to 1 deal
3-night south america cruise
$732
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Mar 03, 2026 from Santos, Brazil
7-night south america cruise
$1,176
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Mar 04, 2026 from Salvador, Brazil
Up to 1 deal
7-night south america cruise
$2,087
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Mar 05, 2026 from Buenos Aires, Argentina
Up to 1 deal
4-night south america cruise
$977
50% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Mar 06, 2026 from Santos, Brazil
9-night south america cruise
$2,043
49% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Mar 06, 2026 from Buenos Aires, Argentina
Up to 1 deal
7-night south america cruise
$1,427
MSC Cruises – MSC Armonia
3.2 (19)
Departs Mar 07, 2026 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$1,464
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Mar 07, 2026 from Santos, Brazil
7-night south america cruise
$1,060
49% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Mar 08, 2026 from Santos, Brazil
Up to 1 deal
3-night south america cruise
$768
47% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Mar 10, 2026 from Santos, Brazil

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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