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Big Savings on Last-Minute Cruises From San Diego

Book Last Minute Cruises from San Diego

Soak up the West Coast sunshine before boarding a last-minute cruise from San Diego. Avoya Travel offers exclusive deals on sailings to Mexico, Hawaii, and the Panama Canal, making your spur-of-the-moment getaway unforgettable.

Showing 1-25 of 31 results

Showing 1-25 of 31 results

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

4-night usa cruise

$219

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

May 02, 2026

Ports:

San Diego → Victoria → Vancouver

Departs May 02, 2026 from San Diego, California

Up to 2 deals including Avoya Exclusives

Secret Rate

Inside From

$219

Special Pricing For:

Other

Top Picks Rank: 6

3-night mexico cruise

$339

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 03, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 03, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$339

Top Picks Rank: 10

3-night mexico cruise

$339

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 10, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 10, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$339

Top Picks Rank: 10

3-night mexico cruise

$379

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 15, 2026

Ports:

San Diego → Ensenada → San Diego

Departs Oct 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$379

Special Pricing For:

Group

Top Picks Rank: 10

4-night mexico cruise

$379

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 06, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Dec 06, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$379

Top Picks Rank: 10

4-night mexico cruise

$405

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 29, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Nov 29, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$405

Special Pricing For:

Group

Top Picks Rank: 10

4-night mexico cruise

$409

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 11, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Oct 11, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$409

Special Pricing For:

Group

Top Picks Rank: 12

7-night mexico cruise

$429

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 08, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 08, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$429

Top Picks Rank: 10

7-night mexico cruise

$439

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 15, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Nov 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$439

Top Picks Rank: 10

7-night mexico cruise

$439

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 01, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 01, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$439

Top Picks Rank: 10

7-night mexico cruise

$499

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 04, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 04, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$499

Top Picks Rank: 11

7-night mexico cruise

$499

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 25, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 25, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$499

Top Picks Rank: 11

7-night mexico cruise

$499

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 13, 2026

Ports:

San Diego → Catalina Island → Ensenada → Cabo San Lucas → San Diego

Departs Dec 13, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$499

Top Picks Rank: 10

7-night mexico cruise

$529

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 18, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Oct 18, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$529

Special Pricing For:

Group

Top Picks Rank: 11

6-night mexico cruise

$759

Norwegian Cruise Line – Norwegian Star

4.1 (162)

5 Star

49%

4 Star

26%

3 Star

12%

2 Star

7%

1 Star

6%

Date:

Dec 20, 2026

Ports:

San Diego → Puerto Vallarta → Cabo San Lucas → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 7 deals including an Avoya Exclusive

Inside From

$759

Top Picks Rank: 9

7-night mexico cruise

$799

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 20, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$799

Special Pricing For:

Group

Top Picks Rank: 10

7-night usa cruise

$799

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 14, 2026

Ports:

San Diego → Catalina Island → San Francisco → Ensenada → San Diego

Departs Nov 14, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$799

Top Picks Rank: 6

7-night mexico cruise

$799

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 21, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Nov 21, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$799

Top Picks Rank: 6

10-night mexico cruise

$849

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 28, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → Mazatlan → Puerto Vallarta → San Diego

Departs Nov 28, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$849

Top Picks Rank: 6

7-night mexico cruise

$849

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 22, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Nov 22, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$849

Special Pricing For:

Group

Top Picks Rank: 11

11-night mexico cruise

$899

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Oct 20, 2026 View Other Dates

Ports:

San Diego → Manzanillo → Puerto Vallarta → Mazatlan → La Paz / Pichilingue → Loreto → Cabo San Lucas → San Diego

Departs Oct 20, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$899

Top Picks Rank: 6

11-night mexico cruise

$899

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Dec 08, 2026 View Other Dates

Ports:

San Diego → Manzanillo → Puerto Vallarta → Mazatlan → La Paz / Pichilingue → Loreto → Cabo San Lucas → San Diego

Departs Dec 08, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$899

Top Picks Rank: 6

7-night mexico cruise

$899

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Oct 08, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Oct 08, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$899

Top Picks Rank: 5

7-night mexico cruise

$949

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 27, 2026

Ports:

San Diego → Mazatlan → La Paz / Pichilingue → Cabo San Lucas → San Diego

Departs Dec 27, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$949

Special Pricing For:

Group

Top Picks Rank: 10

7-night mexico cruise

$999

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Dec 19, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Dec 19, 2026 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Avoya Exclusive Rate

Inside From

$999

Special Pricing For:

Group

Top Picks Rank: 6

Showing 25 of 31 results

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FAQ's

What destinations can I reach from San Diego on a last-minute cruise?

Cruises from San Diego often sail to Mexico’s Riviera ports like Cabo San Lucas and Puerto Vallarta, as well as Hawaii and the Panama Canal. Some longer itineraries even cross the Pacific.

Which cruise lines sail from San Diego?

Major lines include Holland America, Princess, Disney, and Celebrity. These lines frequently release last-minute promotions with Avoya-exclusive perks.

Can I book a Hawaii cruise last-minute from San Diego?

Absolutely. Many 14- to 16-night Hawaii sailings depart from San Diego, and Avoya often has exclusive last-minute offers.

What makes San Diego a convenient port for last-minute cruises?

The port is close to downtown, just minutes from San Diego International Airport, and surrounded by hotels and attractions, making last-minute travel easy and stress-free.

Are family-friendly last-minute cruises available from San Diego?

Yes! Disney Cruise Line, Carnival, and Holland America all offer family-friendly itineraries with kids’ clubs, pools, and fun excursions in Mexico.

Can I find luxury last-minute cruises from San Diego?

Yes. Lines like Celebrity and Holland America sail from San Diego with last-minute deals that can include free beverage packages, onboard credit, and reduced airfare.

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