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Big Savings on Last-Minute Cruises From San Diego

Book Last Minute Cruises from San Diego

Soak up the West Coast sunshine before boarding a last-minute cruise from San Diego. Avoya Travel offers exclusive deals on sailings to Mexico, Hawaii, and the Panama Canal, making your spur-of-the-moment getaway unforgettable.

Showing 1-25 of 44 results

Showing 1-25 of 44 results

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

7-night mexico cruise

$911

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 22, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Nov 22, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$911

Special Pricing For:

Group

Top Picks Rank: 13

3-night mexico cruise

$437

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 15, 2026

Ports:

San Diego → Ensenada → San Diego

Departs Oct 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$437

Special Pricing For:

Group

Top Picks Rank: 12

7-night mexico cruise

$1,091

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 27, 2026

Ports:

San Diego → Mazatlan → La Paz / Pichilingue → Cabo San Lucas → San Diego

Departs Dec 27, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,091

Special Pricing For:

Group

Top Picks Rank: 12

7-night mexico cruise

$649

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 04, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 04, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$649

Top Picks Rank: 11

7-night mexico cruise

$626

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 18, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Oct 18, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$626

Special Pricing For:

Group

Top Picks Rank: 11

7-night mexico cruise

$657

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 25, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 25, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$657

Top Picks Rank: 11

4-night mexico cruise

$521

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 11, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Oct 11, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$521

Special Pricing For:

Group

Top Picks Rank: 10

7-night mexico cruise

$629

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 01, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 01, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$629

Top Picks Rank: 10

7-night mexico cruise

$629

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 08, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 08, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$629

Top Picks Rank: 10

7-night mexico cruise

$626

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 15, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Nov 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$626

Top Picks Rank: 10

4-night mexico cruise

$419

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 29, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Nov 29, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$419

Special Pricing For:

Group

Top Picks Rank: 10

3-night mexico cruise

$364

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 03, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 03, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$364

Top Picks Rank: 10

4-night mexico cruise

$399

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 06, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Dec 06, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$399

Top Picks Rank: 10

3-night mexico cruise

$349

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 10, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 10, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$349

Top Picks Rank: 10

7-night mexico cruise

$627

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 13, 2026

Ports:

San Diego → Catalina Island → Ensenada → Cabo San Lucas → San Diego

Departs Dec 13, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$627

Top Picks Rank: 10

7-night mexico cruise

$989

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 20, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$989

Special Pricing For:

Group

Top Picks Rank: 10

6-night mexico cruise

$909

Norwegian Cruise Line – Norwegian Star

4.1 (162)

5 Star

49%

4 Star

26%

3 Star

12%

2 Star

7%

1 Star

6%

Date:

Dec 20, 2026

Ports:

San Diego → Puerto Vallarta → Cabo San Lucas → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 7 deals including an Avoya Exclusive

Inside From

$909

Top Picks Rank: 9

7-night mexico cruise

$559

Norwegian Cruise Line – Norwegian Jade

4.2 (153)

5 Star

56%

4 Star

23%

3 Star

10%

2 Star

3%

1 Star

8%

Date:

Mar 28, 2026

Ports:

San Diego → Mazatlan → Puerto Vallarta → Cabo San Lucas → San Diego

Departs Mar 28, 2026 from San Diego, California

Up to 7 deals including an Avoya Exclusive

Inside From

$559

Top Picks Rank: 7

7-night usa cruise

$799

Holland America – Nieuw Amsterdam

4.3 (198)

5 Star

66%

4 Star

15%

3 Star

10%

2 Star

4%

1 Star

5%

Date:

Apr 04, 2026

Ports:

San Diego → Catalina Island → San Francisco → Astoria → Victoria → Vancouver

Departs Apr 04, 2026 from San Diego, California

Up to 3 deals including Avoya Exclusives

Secret Rate

Inside From

$799

Special Pricing For:

Other

Top Picks Rank: 7

11-night mexico cruise

$1,199

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Apr 07, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → Mazatlan → Puerto Vallarta → Manzanillo → San Diego

Departs Apr 07, 2026 from San Diego, California

Up to 3 deals including Avoya Exclusives

Inside From

$1,199

Top Picks Rank: 7

8-night usa cruise

$539

Norwegian Cruise Line – Norwegian Jade

4.2 (153)

5 Star

56%

4 Star

23%

3 Star

10%

2 Star

3%

1 Star

8%

Date:

Apr 11, 2026

Ports:

San Diego → San Francisco → Astoria → Seattle → Victoria → Vancouver

Departs Apr 11, 2026 from San Diego, California

Up to 7 deals including an Avoya Exclusive

Inside From

$539

Top Picks Rank: 7

7-night mexico cruise

$1,099

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Apr 18, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Apr 18, 2026 from San Diego, California

Up to 3 deals including Avoya Exclusives

Oceanview From

$1,099

Top Picks Rank: 7

14-night mexico cruise

$1,814

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Apr 18, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → Mazatlan → Puerto Vallarta → San Diego

Departs Apr 18, 2026 from San Diego, California

Up to 3 deals including Avoya Exclusives

Oceanview From

$1,814

Top Picks Rank: 7

7-night mexico cruise

$739

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Apr 25, 2026

Ports:

San Diego → Cabo San Lucas → Mazatlan → Puerto Vallarta → San Diego

Departs Apr 25, 2026 from San Diego, California

Up to 2 deals including Avoya Exclusives

Inside From

$739

Top Picks Rank: 7

11-night mexico cruise

$899

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Apr 25, 2026

Ports:

San Diego → Cabo San Lucas → Mazatlan → Puerto Vallarta → Victoria → Vancouver

Departs Apr 25, 2026 from San Diego, California

Up to 3 deals including Avoya Exclusives

Secret Rate

Inside From

$899

Special Pricing For:

Other

Top Picks Rank: 7

Showing 25 of 44 results

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FAQ's

What destinations can I reach from San Diego on a last-minute cruise?

Cruises from San Diego often sail to Mexico’s Riviera ports like Cabo San Lucas and Puerto Vallarta, as well as Hawaii and the Panama Canal. Some longer itineraries even cross the Pacific.

Which cruise lines sail from San Diego?

Major lines include Holland America, Princess, Disney, and Celebrity. These lines frequently release last-minute promotions with Avoya-exclusive perks.

Can I book a Hawaii cruise last-minute from San Diego?

Absolutely. Many 14- to 16-night Hawaii sailings depart from San Diego, and Avoya often has exclusive last-minute offers.

What makes San Diego a convenient port for last-minute cruises?

The port is close to downtown, just minutes from San Diego International Airport, and surrounded by hotels and attractions, making last-minute travel easy and stress-free.

Are family-friendly last-minute cruises available from San Diego?

Yes! Disney Cruise Line, Carnival, and Holland America all offer family-friendly itineraries with kids’ clubs, pools, and fun excursions in Mexico.

Can I find luxury last-minute cruises from San Diego?

Yes. Lines like Celebrity and Holland America sail from San Diego with last-minute deals that can include free beverage packages, onboard credit, and reduced airfare.

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