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Big Savings on Last-Minute Cruises From San Diego

Book Last Minute Cruises from San Diego

Soak up the West Coast sunshine before boarding a last-minute cruise from San Diego. Avoya Travel offers exclusive deals on sailings to Mexico, Hawaii, and the Panama Canal, making your spur-of-the-moment getaway unforgettable.

Showing 1-25 of 30 results

Showing 1-25 of 30 results

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Help Me Plan

7-night mexico cruise

$862

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 22, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Nov 22, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$862

Special Pricing For:

Group

Top Picks Rank: 14

4-night mexico cruise

$411

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 11, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Oct 11, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$411

Special Pricing For:

Group

Top Picks Rank: 13

7-night mexico cruise

$556

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 18, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Oct 18, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$556

Special Pricing For:

Group

Top Picks Rank: 13

4-night mexico cruise

$362

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 29, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Nov 29, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$362

Special Pricing For:

Group

Top Picks Rank: 13

7-night mexico cruise

$1,091

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 27, 2026

Ports:

San Diego → Mazatlan → La Paz / Pichilingue → Cabo San Lucas → San Diego

Departs Dec 27, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,091

Special Pricing For:

Group

Top Picks Rank: 13

7-night mexico cruise

$519

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 04, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 04, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$519

Top Picks Rank: 11

3-night mexico cruise

$362

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 15, 2026

Ports:

San Diego → Ensenada → San Diego

Departs Oct 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$362

Special Pricing For:

Group

Top Picks Rank: 11

7-night mexico cruise

$490

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Oct 25, 2026 View Other Dates

Ports:

San Diego → La Paz / Pichilingue → Cabo San Lucas → Ensenada → San Diego

Departs Oct 25, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$490

Top Picks Rank: 11

7-night mexico cruise

$512

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 01, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 01, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$512

Top Picks Rank: 11

7-night mexico cruise

$501

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 08, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → Mazatlan → San Diego

Departs Nov 08, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$501

Top Picks Rank: 11

7-night mexico cruise

$511

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Nov 15, 2026 View Other Dates

Ports:

San Diego → Ensenada → Cabo San Lucas → La Paz / Pichilingue → San Diego

Departs Nov 15, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$511

Top Picks Rank: 11

3-night mexico cruise

$322

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 03, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 03, 2026 from San Diego, California

Up to 5 deals including Avoya Exclusives

Inside From

$322

Top Picks Rank: 11

4-night mexico cruise

$362

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 06, 2026 View Other Dates

Ports:

San Diego → Catalina Island → Ensenada → San Diego

Departs Dec 06, 2026 from San Diego, California

Up to 5 deals including Avoya Exclusives

Inside From

$362

Top Picks Rank: 11

3-night mexico cruise

$311

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 10, 2026 View Other Dates

Ports:

San Diego → Ensenada → San Diego

Departs Dec 10, 2026 from San Diego, California

Up to 5 deals including Avoya Exclusives

Inside From

$311

Top Picks Rank: 11

7-night mexico cruise

$531

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 13, 2026

Ports:

San Diego → Catalina Island → Ensenada → Cabo San Lucas → San Diego

Departs Dec 13, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Inside From

$531

Top Picks Rank: 11

7-night mexico cruise

$762

Royal Caribbean – Serenade of the Seas

4.5 (214)

5 Star

64%

4 Star

27%

3 Star

5%

2 Star

3%

1 Star

2%

Date:

Dec 20, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Mazatlan → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 4 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$762

Special Pricing For:

Group

Top Picks Rank: 11

6-night mexico cruise

$699

Norwegian Cruise Line – Norwegian Star

4.1 (162)

5 Star

49%

4 Star

26%

3 Star

12%

2 Star

7%

1 Star

6%

Date:

Dec 20, 2026

Ports:

San Diego → Puerto Vallarta → Cabo San Lucas → San Diego

Departs Dec 20, 2026 from San Diego, California

Up to 8 deals including Avoya Exclusives

Inside From

$699

Top Picks Rank: 9

10-night mexico cruise

$1,528

Norwegian Cruise Line – Norwegian Star

4.1 (162)

5 Star

49%

4 Star

26%

3 Star

12%

2 Star

7%

1 Star

6%

Date:

Dec 31, 2026

Ports:

Hotel Check-in/check Out → San Diego → Cabo San Lucas → Puerto Vallarta → Mazatlan → San Diego

Departs Dec 31, 2026 from San Diego, California

Up to 5 deals including Avoya Exclusives

Inside From

$1,528

Top Picks Rank: 8

11-night mexico cruise

$1,234

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Oct 20, 2026 View Other Dates

Ports:

San Diego → Manzanillo → Puerto Vallarta → Mazatlan → La Paz / Pichilingue → Loreto → Cabo San Lucas → San Diego

Departs Oct 20, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Inside From

$1,234

Top Picks Rank: 7

7-night usa cruise

$979

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 14, 2026

Ports:

San Diego → Catalina Island → San Francisco → Ensenada → San Diego

Departs Nov 14, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Avoya Exclusive Rate

Inside From

$979

Special Pricing For:

Group

Top Picks Rank: 7

7-night mexico cruise

$944

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 21, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Nov 21, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Avoya Exclusive Rate

Inside From

$944

Special Pricing For:

Group

Top Picks Rank: 7

10-night mexico cruise

$949

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Nov 28, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → Mazatlan → Puerto Vallarta → San Diego

Departs Nov 28, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Inside From

$949

Top Picks Rank: 7

12-night mexico cruise

$1,119

Holland America – Zaandam

4.5 (132)

5 Star

59%

4 Star

31%

3 Star

8%

2 Star

2%

1 Star

1%

Date:

Dec 07, 2026

Ports:

San Diego → Cabo San Lucas → Loreto → Guaymas → Topolobampo → La Paz / Pichilingue → Mazatlan → Puerto Vallarta → Ensenada → San Diego

San Diego → Cabo San Lucas → Loreto → Guaymas → Topolobampo → La Paz / Pichilingue → Mazatlan → Puerto Vallarta → Ensenada → San Diego

Departs Dec 07, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Inside From

$1,119

Top Picks Rank: 7

11-night mexico cruise

$984

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Dec 08, 2026 View Other Dates

Ports:

San Diego → Manzanillo → Puerto Vallarta → Mazatlan → La Paz / Pichilingue → Loreto → Cabo San Lucas → San Diego

Departs Dec 08, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Inside From

$984

Top Picks Rank: 7

7-night mexico cruise

$1,044

Holland America – Koningsdam

4.2 (239)

5 Star

51%

4 Star

29%

3 Star

10%

2 Star

6%

1 Star

3%

Date:

Dec 19, 2026

Ports:

San Diego → Cabo San Lucas → La Paz / Pichilingue → Loreto → San Diego

Departs Dec 19, 2026 from San Diego, California

Up to 2 deals including an Avoya Exclusive

Avoya Exclusive Rate

Inside From

$1,044

Special Pricing For:

Group

Top Picks Rank: 7

Showing 25 of 30 results

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FAQ's

What destinations can I reach from San Diego on a last-minute cruise?

Cruises from San Diego often sail to Mexico’s Riviera ports like Cabo San Lucas and Puerto Vallarta, as well as Hawaii and the Panama Canal. Some longer itineraries even cross the Pacific.

Which cruise lines sail from San Diego?

Major lines include Holland America, Princess, Disney, and Celebrity. These lines frequently release last-minute promotions with Avoya-exclusive perks.

Can I book a Hawaii cruise last-minute from San Diego?

Absolutely. Many 14- to 16-night Hawaii sailings depart from San Diego, and Avoya often has exclusive last-minute offers.

What makes San Diego a convenient port for last-minute cruises?

The port is close to downtown, just minutes from San Diego International Airport, and surrounded by hotels and attractions, making last-minute travel easy and stress-free.

Are family-friendly last-minute cruises available from San Diego?

Yes! Disney Cruise Line, Carnival, and Holland America all offer family-friendly itineraries with kids’ clubs, pools, and fun excursions in Mexico.

Can I find luxury last-minute cruises from San Diego?

Yes. Lines like Celebrity and Holland America sail from San Diego with last-minute deals that can include free beverage packages, onboard credit, and reduced airfare.

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