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MSC Cruises to Africa

MSC Cruises Africa cruises are diverse and exciting, exploring everything from ancient pyramids in Egypt to guided safaris in natural reserves. Onboard the MSC Sinfonia, which sails all of MSC Cruise line’s African Cruises, guests will enjoy distinct Italian style, comfortable accommodations, countless activities, and more. In addition, on all MSC Cruises to Africa, kids sail free!

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Armonia itinerary map

3-night africa cruise

Oceanview From

$530

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Nov 27, 2026 View Other Dates →

Ports:

Durban → Portuguese Island (Inhaca Archipelago) Mozambique → Durban

Departs Nov 27, 2026 from Durban, South Africa

Up to 3 deals

Oceanview From

$530

47% Off List

List Price

$993

View Expanded Details

MSC Cruises MSC Armonia itinerary map

4-night africa cruise

Inside From

$594

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Nov 30, 2026

Ports:

Durban → Pomene Mozambique → Durban

Departs Nov 30, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$594

47% Off List

List Price

$1,119

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

6-night africa cruise

Inside From

$409

60% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 07, 2026

Ports:

Rome (Civitavecchia) → Las Palmas → Santa Cruz de La Palma Spain → Santa Cruz de Tenerife

Departs Dec 07, 2026 from Rome (Civitavecchia), Italy

Up to 4 deals

Inside From

$409

60% Off List

List Price

$1,017

View Expanded Details

MSC Cruises MSC Armonia itinerary map

4-night africa cruise

Inside From

$594

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 07, 2026 View Other Dates →

Ports:

Durban → Pomene Mozambique → Durban

Departs Dec 07, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$594

47% Off List

List Price

$1,119

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

8-night africa cruise

Inside From

$741

47% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 07, 2026

Ports:

Departs Dec 07, 2026 from Rome (Civitavecchia), Italy

Up to 4 deals

Inside From

$741

47% Off List

List Price

$1,400

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

10-night africa cruise

Inside From

$783

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 07, 2026

Ports:

Departs Dec 07, 2026 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$783

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

11-night africa cruise

Inside From

$885

40% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 07, 2026

Ports:

Departs Dec 07, 2026 from Rome (Civitavecchia), Italy

Up to 4 deals

Inside From

$885

40% Off List

List Price

$1,472

View Expanded Details

MSC Cruises MSC Armonia itinerary map

3-night africa cruise

Inside From

$503

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 11, 2026 View Other Dates →

Ports:

Durban → Portuguese Island (Inhaca Archipelago) Mozambique → Durban

Departs Dec 11, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$503

47% Off List

List Price

$941

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$629

67% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 13, 2026 View Other Dates →

Ports:

Departs Dec 13, 2026 from Santa Cruz de Tenerife, Spain

Up to 5 deals

Inside From

$629

67% Off List

List Price

$1,892

View Expanded Details

MSC Cruises MSC Armonia itinerary map

4-night africa cruise

Inside From

$663

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 14, 2026 View Other Dates →

Ports:

Durban → Pomene Mozambique → Durban

Departs Dec 14, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$663

47% Off List

List Price

$1,251

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Balcony From

$1,331

46% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 15, 2026 View Other Dates →

Ports:

Departs Dec 15, 2026 from Funchal, Madeira Islands, Portugal

Up to 5 deals

Balcony From

$1,331

46% Off List

List Price

$2,456

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$841

63% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 17, 2026 View Other Dates →

Ports:

Departs Dec 17, 2026 from Lanzarote, Spain

Up to 4 deals

Inside From

$841

63% Off List

List Price

$2,248

View Expanded Details

MSC Cruises MSC Armonia itinerary map

3-night africa cruise

Oceanview From

$613

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 18, 2026 View Other Dates →

Ports:

Durban → Portuguese Island (Inhaca Archipelago) Mozambique → Durban

Departs Dec 18, 2026 from Durban, South Africa

Up to 3 deals

Oceanview From

$613

47% Off List

List Price

$1,151

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$1,037

46% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 18, 2026 View Other Dates →

Ports:

Departs Dec 18, 2026 from Las Palmas, Spain

Up to 4 deals

Inside From

$1,037

46% Off List

List Price

$1,936

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$1,009

44% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 20, 2026 View Other Dates →

Ports:

Departs Dec 20, 2026 from Santa Cruz de Tenerife, Spain

Up to 4 deals

Inside From

$1,009

44% Off List

List Price

$1,797

View Expanded Details

MSC Cruises MSC Armonia itinerary map

5-night africa cruise

Inside From

$919

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 21, 2026 View Other Dates →

Ports:

Durban → Pomene Mozambique → Portuguese Island (Inhaca Archipelago) Mozambique → Durban

Departs Dec 21, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$919

47% Off List

List Price

$1,745

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$951

53% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 22, 2026 View Other Dates →

Ports:

Funchal → Lanzarote → Las Palmas → Santa Cruz de La Palma Spain → Santa Cruz de Tenerife → Funchal

Departs Dec 22, 2026 from Funchal, Madeira Islands, Portugal

Up to 5 deals

Inside From

$951

53% Off List

List Price

$2,013

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$1,226

58% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 24, 2026 View Other Dates →

Ports:

Lanzarote → Las Palmas → Santa Cruz de La Palma Spain → Santa Cruz de Tenerife → Funchal → Lanzarote

Departs Dec 24, 2026 from Lanzarote, Spain

Up to 4 deals

Inside From

$1,226

58% Off List

List Price

$2,914

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$1,157

48% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 25, 2026 View Other Dates →

Ports:

Las Palmas → Santa Cruz de La Palma Spain → Santa Cruz de Tenerife → Funchal → Lanzarote → Las Palmas

Departs Dec 25, 2026 from Las Palmas, Spain

Up to 4 deals

Inside From

$1,157

48% Off List

List Price

$2,246

View Expanded Details

MSC Cruises MSC Armonia itinerary map

12-night africa cruise

Inside From

$2,291

47% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Dec 26, 2026

Ports:

Durban → Mauritius → La Possession Reunion → Portuguese Island (Inhaca Archipelago) Mozambique → Durban

Departs Dec 26, 2026 from Durban, South Africa

Up to 3 deals

Inside From

$2,291

47% Off List

List Price

$4,323

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$1,459

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 27, 2026 View Other Dates →

Ports:

Departs Dec 27, 2026 from Santa Cruz de Tenerife, Spain

Up to 4 deals

Inside From

$1,459

50% Off List

List Price

$2,892

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$951

59% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Dec 29, 2026 View Other Dates →

Ports:

Funchal → Lanzarote → Las Palmas → Puerto Del Rosario/Fuerteventura Spain → Santa Cruz de Tenerife → Funchal

Departs Dec 29, 2026 from Funchal, Madeira Islands, Portugal

Up to 5 deals

Inside From

$951

59% Off List

List Price

$2,311

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$927

51% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jan 01, 2027 View Other Dates →

Ports:

Las Palmas → Puerto Del Rosario/Fuerteventura Spain → Santa Cruz de Tenerife → Funchal → Lanzarote → Las Palmas

Departs Jan 01, 2027 from Las Palmas, Spain

Up to 4 deals

Inside From

$927

51% Off List

List Price

$1,874

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$569

70% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jan 03, 2027 View Other Dates →

Ports:

Departs Jan 03, 2027 from Santa Cruz de Tenerife, Spain

Up to 5 deals

Inside From

$569

70% Off List

List Price

$1,875

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night africa cruise

Inside From

$921

41% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jan 05, 2027 View Other Dates →

Ports:

Departs Jan 05, 2027 from Funchal, Madeira Islands, Portugal

Up to 5 deals

Inside From

$921

41% Off List

List Price

$1,560

View Expanded Details

Showing 1-25 of 168 results

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