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MSC Cruises to Africa

MSC Cruises Africa cruises are diverse and exciting, exploring everything from ancient pyramids in Egypt to guided safaris in natural reserves. Onboard the MSC Sinfonia, which sails all of MSC Cruise line’s African Cruises, guests will enjoy distinct Italian style, comfortable accommodations, countless activities, and more. In addition, on all MSC Cruises to Africa, kids sail free!

Showing 26-50 of 92 results
Roundtrip
4-Night Africa Cruise
$339
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Jan 13, 2025 from Durban, South Africa
Up to 2 deals
Roundtrip
3-Night Africa Cruise
$229
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Jan 17, 2025 from Durban, South Africa
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$419
38% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Jan 20, 2025 from Las Palmas, Spain
Roundtrip
7-Night Africa Cruise
$419
38% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Jan 23, 2025 from Funchal, Madeira Islands, Portugal
Roundtrip
7-Night Africa Cruise
$419
38% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Jan 26, 2025 from Santa Cruz de Tenerife, Spain
Up to 1 deal
Roundtrip
3-Night Africa Cruise
$229
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Jan 31, 2025 from Durban, South Africa
Up to 2 deals
Roundtrip
4-Night Africa Cruise
$339
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 03, 2025 from Durban, South Africa
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$539
41% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 09, 2025 from Santa Cruz de Tenerife, Spain
Roundtrip
4-Night Africa Cruise
$339
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 10, 2025 from Durban, South Africa
Up to 2 deals
Roundtrip
3-Night Africa Cruise
$229
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 14, 2025 from Durban, South Africa
Up to 1 deal
Roundtrip
7-Night Africa Cruise
$539
41% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 16, 2025 from Santa Cruz de Tenerife, Spain
Up to 1 deal
Roundtrip
8-Night Africa Cruise
$589
42% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 20, 2025 from Funchal, Madeira Islands, Portugal
Roundtrip
3-Night Africa Cruise
$229
43% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 21, 2025 from Durban, South Africa
Up to 2 deals
Roundtrip
7-Night Africa Cruise
$539
41% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 23, 2025 from Santa Cruz de Tenerife, Spain
Up to 1 deal
Roundtrip
6-Night Africa Cruise
$449
42% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 28, 2025 from Funchal, Madeira Islands, Portugal
Up to 1 deal
Roundtrip
7-Night Africa Cruise
$539
41% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 02, 2025 from Santa Cruz de Tenerife, Spain
Roundtrip
7-Night Africa Cruise
$579
42% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 06, 2025 from Funchal, Madeira Islands, Portugal
Up to 1 deal
Roundtrip
7-Night Africa Cruise
$569
42% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 09, 2025 from Santa Cruz de Tenerife, Spain
Up to 1 deal
Roundtrip
4-Night Africa Cruise
$409
45% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 12, 2025 from Cape Town, South Africa
Up to 3 deals
Roundtrip
7-Night Africa Cruise
$709
44% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 13, 2025 from Funchal, Madeira Islands, Portugal
Up to 1 deal
Roundtrip
7-Night Africa Cruise
$569
42% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 16, 2025 from Santa Cruz de Tenerife, Spain
6-Night Africa Cruise
$469
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 17, 2025 from Las Palmas, Spain
10-Night Africa Cruise
$919
44% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 17, 2025 from Las Palmas, Spain
9-Night Africa Cruise
$829
44% Off List
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 23, 2025 from Santa Cruz de Tenerife, Tenerife, Canary Islands, Spain
Roundtrip
3-Night Africa Cruise
$269
44% Off List
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 27, 2025 from Cape Town, South Africa
Up to 2 deals
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