No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees.

No Avoya Fees.

Click Here!

Menu

Speak To A Vacation Planner Now

1-888-447-8459

feature image

MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard.

Showing 1-25 of 3,896 results

Sort By

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$752

57% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Apr 18, 2027 View Other Dates →

Ports:

Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille → Genoa → Rome (Civitavecchia)

Departs Apr 18, 2027 from Rome (Civitavecchia), Italy

Up to 4 deals

Inside From

$752

57% Off List

List Price

$1,746

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$735

63% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Apr 25, 2027 View Other Dates →

Ports:

Livorno → Marseille → Barcelona → La Goulette → Palermo → Naples → Livorno

Departs Apr 25, 2027 from Livorno, Italy

Up to 4 deals

Inside From

$735

63% Off List

List Price

$2,007

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,013

40% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Apr 25, 2027 View Other Dates →

Ports:

Cagliari → Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari

Departs Apr 25, 2027 from Cagliari, Sardinia, Italy

Up to 4 deals

Inside From

$1,013

40% Off List

List Price

$1,692

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,000

51% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Apr 26, 2027 View Other Dates →

Ports:

Marseille → Genoa → Naples → Palermo → Valletta → Barcelona → Marseille

Departs Apr 26, 2027 from Marseille, France

Up to 4 deals

Inside From

$1,000

51% Off List

List Price

$2,048

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$860

58% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Apr 27, 2027

Ports:

Genoa → Naples → Palermo → Valletta → Barcelona → Marseille → Genoa

Departs Apr 27, 2027 from Genoa, Italy

Up to 4 deals

Inside From

$860

58% Off List

List Price

$2,036

View Expanded Details

MSC Cruises MSC Orchestra itinerary map

7-night mediterranean cruise

Inside From

$1,040

49% Off List

MSC Cruises – MSC Orchestra

4.04 Reviews

Date:

Apr 27, 2027 View Other Dates →

Ports:

Piraeus (Athens) → Katakolon → Cefalonia/Argostoli Greece → Corfu → Bari → Santorini → Piraeus (Athens)

Departs Apr 27, 2027 from Piraeus (Athens), Greece

Up to 4 deals

Inside From

$1,040

49% Off List

List Price

$2,036

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$864

57% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 02, 2027 View Other Dates →

Ports:

Livorno → Marseille → Barcelona → La Goulette → Palermo → Naples → Livorno

Departs May 02, 2027 from Livorno, Italy

Up to 4 deals

Inside From

$864

57% Off List

List Price

$1,987

View Expanded Details

MSC Cruises MSC Lirica itinerary map

7-night mediterranean cruise

Inside From

$769

60% Off List

MSC Cruises – MSC Lirica

4.36 Reviews

Date:

May 08, 2027 View Other Dates →

Ports:

Venice → Kotor → Mykonos → Syros Greece → Ancona → Venice

Departs May 08, 2027 from Venice, Italy

Up to 4 deals

Inside From

$769

60% Off List

List Price

$1,941

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$833

51% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

May 08, 2027 View Other Dates →

Ports:

Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille → Genoa

Departs May 08, 2027 from Genoa, Italy

Up to 4 deals

Inside From

$833

51% Off List

List Price

$1,705

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,686

48% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

May 09, 2027 View Other Dates →

Ports:

Marseille → Malaga → Casablanca → Cadiz → Gibraltar → Alicante → Rome (Civitavecchia) → Genoa → Marseille

Departs May 09, 2027 from Marseille, France

Up to 3 deals

Inside From

$1,686

48% Off List

List Price

$3,249

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,093

57% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

May 10, 2027 View Other Dates →

Ports:

Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona → Marseille → Genoa

Departs May 10, 2027 from Genoa, Italy

Up to 4 deals

Inside From

$1,093

57% Off List

List Price

$2,513

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,022

52% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

May 13, 2027 View Other Dates →

Ports:

Palermo → Valletta → Barcelona → Marseille → Genoa → Naples → Palermo

Departs May 13, 2027 from Palermo, Italy

Up to 4 deals

Inside From

$1,022

52% Off List

List Price

$2,108

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,093

56% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

May 16, 2027 View Other Dates →

Ports:

Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona → Marseille

Departs May 16, 2027 from Marseille, France

Up to 4 deals

Inside From

$1,093

56% Off List

List Price

$2,496

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,371

48% Off List

MSC Cruises – MSC World Asia

Date:

May 16, 2027 View Other Dates →

Ports:

Genoa → Naples → Messina → Valletta → Barcelona → Marseille → Genoa

Departs May 16, 2027 from Genoa, Italy

Up to 3 deals

Inside From

$1,371

48% Off List

List Price

$2,655

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$917

56% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 17, 2027 View Other Dates →

Ports:

Marseille → Barcelona → La Goulette → Palermo → Naples → Livorno → Marseille

Departs May 17, 2027 from Marseille, France

Up to 4 deals

Inside From

$917

56% Off List

List Price

$2,108

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,702

48% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

May 18, 2027 View Other Dates →

Ports:

Genoa → Marseille → Malaga → Tangier → Portimao → Ceuta → Alicante → Rome (Civitavecchia) → Genoa

Departs May 18, 2027 from Genoa, Italy

Up to 3 deals

Inside From

$1,702

48% Off List

List Price

$3,266

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,022

52% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

May 19, 2027 View Other Dates →

Ports:

Naples → Palermo → Valletta → Barcelona → Marseille → Genoa → Naples

Departs May 19, 2027 from Naples, Italy

Up to 4 deals

Inside From

$1,022

52% Off List

List Price

$2,108

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$992

55% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 21, 2027 View Other Dates →

Ports:

Palermo → Naples → Livorno → Marseille → Barcelona → La Goulette → Palermo

Departs May 21, 2027 from Palermo, Italy

Up to 4 deals

Inside From

$992

55% Off List

List Price

$2,188

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,113

55% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

May 23, 2027 View Other Dates →

Ports:

Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona → Marseille

Departs May 23, 2027 from Marseille, France

Up to 4 deals

Inside From

$1,113

55% Off List

List Price

$2,496

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$1,140

48% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

May 23, 2027 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs May 23, 2027 from Venice, Italy

Up to 4 deals

Inside From

$1,140

48% Off List

List Price

$2,200

View Expanded Details

MSC Cruises MSC Splendida itinerary map

9-night mediterranean cruise

Inside From

$1,467

53% Off List

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

May 24, 2027 View Other Dates →

Ports:

Istanbul → Corfu → Bari → Trieste → Katakolon → Piraeus (Athens) → Kusadasi → Istanbul

Departs May 24, 2027 from Istanbul, Turkey

Up to 4 deals

Inside From

$1,467

53% Off List

List Price

$3,148

View Expanded Details

MSC Cruises MSC Splendida itinerary map

9-night mediterranean cruise

Inside From

$1,487

52% Off List

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

May 28, 2027 View Other Dates →

Ports:

Trieste → Katakolon → Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari → Trieste

Departs May 28, 2027 from Trieste, Italy

Up to 4 deals

Inside From

$1,487

52% Off List

List Price

$3,098

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$952

58% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 29, 2027 View Other Dates →

Ports:

Naples → Livorno → Marseille → Barcelona → La Goulette → Palermo → Naples

Departs May 29, 2027 from Naples, Italy

Up to 4 deals

Inside From

$952

58% Off List

List Price

$2,248

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$990

54% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 31, 2027 View Other Dates →

Ports:

Marseille → Barcelona → La Goulette → Palermo → Naples → Livorno → Marseille

Departs May 31, 2027 from Marseille, France

Up to 4 deals

Inside From

$990

54% Off List

List Price

$2,168

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,017

53% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

May 31, 2027 View Other Dates →

Ports:

Marseille → Genoa → Naples → Palermo → Valletta → Barcelona → Marseille

Departs May 31, 2027 from Marseille, France

Up to 4 deals

Inside From

$1,017

53% Off List

List Price

$2,168

View Expanded Details

Showing 1-25 of 3,896 results

1
2
3
4
5
…156

Don't Miss the Latest Deals!

Save favorite vacations & searches
Early access to promotions
Exclusive deals, discounts & prices
Plus more!

Talk to a Vacation Planner

Call at 1-888-447-8459

1-888-447-8459

or click here to submit a form and we will connect you with a Personal Travel Advisor that specializes in the type of travel you are interested in.

Why Choose Avoya?

From powerful online search, to specialized vacation planning services, and exclusive deals and extras - discover what makes Avoya Travel a different, better type of travel company.

About Avoya Travel