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MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,691

49% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Sep 27, 2028 View Other Dates →

Ports:

Lisbon → Alicante → Mahon → Olbia → Genoa → Marseille → Malaga → Cadiz → Lisbon

Departs Sep 27, 2028 from Lisbon, Portugal

Up to 2 deals

Inside From

$1,691

49% Off List

List Price

$3,334

View Expanded Details

MSC Cruises MSC Seaview itinerary map

9-night mediterranean cruise

Inside From

$1,724

49% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Sep 27, 2028 View Other Dates →

Ports:

Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari → Trieste → Split → Piraeus (Athens)

Departs Sep 27, 2028 from Piraeus (Athens), Greece

Up to 2 deals

Inside From

$1,724

49% Off List

List Price

$3,410

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,190

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Sep 28, 2028 View Other Dates →

Ports:

Naples → Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples

Departs Sep 28, 2028 from Naples, Italy

Up to 1 deal

Inside From

$1,190

50% Off List

List Price

$2,368

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$1,170

50% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Sep 29, 2028 View Other Dates →

Ports:

Palermo → Naples → Livorno → Marseille → Barcelona → La Goulette → Palermo

Departs Sep 29, 2028 from Palermo, Italy

Up to 2 deals

Inside From

$1,170

50% Off List

List Price

$2,328

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,446

50% Off List

MSC Cruises – MSC World Asia

Date:

Sep 29, 2028 View Other Dates →

Ports:

Barcelona → Marseille → Genoa → Naples → Messina → Valletta → Barcelona

Departs Sep 29, 2028 from Barcelona, Spain

Up to 2 deals

Inside From

$1,446

50% Off List

List Price

$2,871

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,643

49% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Sep 29, 2028 View Other Dates →

Ports:

Alicante → Mahon → Olbia → Genoa → Marseille → Malaga → Cadiz → Lisbon → Alicante

Departs Sep 29, 2028 from Alicante, Spain

Up to 2 deals

Inside From

$1,643

49% Off List

List Price

$3,240

View Expanded Details

MSC Cruises MSC Seaview itinerary map

9-night mediterranean cruise

Inside From

$1,678

49% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Sep 29, 2028 View Other Dates →

Ports:

Istanbul → Corfu → Bari → Trieste → Split → Piraeus (Athens) → Kusadasi → Istanbul

Departs Sep 29, 2028 from Istanbul, Turkey

Up to 2 deals

Inside From

$1,678

49% Off List

List Price

$3,288

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,236

50% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Sep 30, 2028 View Other Dates →

Ports:

Barcelona → Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona

Departs Sep 30, 2028 from Barcelona, Spain

Up to 2 deals

Inside From

$1,236

50% Off List

List Price

$2,451

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,440

50% Off List

MSC Cruises – MSC World Asia

Date:

Sep 30, 2028 View Other Dates →

Ports:

Marseille → Genoa → Naples → Messina → Valletta → Barcelona → Marseille

Departs Sep 30, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,440

50% Off List

List Price

$2,868

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$1,040

49% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Oct 01, 2028 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs Oct 01, 2028 from Venice, Italy

Up to 2 deals

Inside From

$1,040

49% Off List

List Price

$2,058

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night mediterranean cruise

Inside From

$1,196

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 01, 2028 View Other Dates →

Ports:

Barcelona → Marseille → Genoa → Naples → Palermo → Valletta → Barcelona

Departs Oct 01, 2028 from Barcelona, Spain

Up to 2 deals

Inside From

$1,196

50% Off List

List Price

$2,371

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,451

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 01, 2028 View Other Dates →

Ports:

Genoa → Naples → Messina → Valletta → Barcelona → Marseille → Genoa

Departs Oct 01, 2028 from Genoa, Italy

Up to 2 deals

Inside From

$1,451

50% Off List

List Price

$2,875

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,049

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Oct 02, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia)

Departs Oct 02, 2028 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$1,049

50% Off List

List Price

$2,088

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$1,100

50% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Oct 02, 2028 View Other Dates →

Ports:

Marseille → Barcelona → La Goulette → Palermo → Naples → Livorno → Marseille

Departs Oct 02, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,100

50% Off List

List Price

$2,188

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,189

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 02, 2028 View Other Dates →

Ports:

Marmaris → Santorini → Naples → Rome (Civitavecchia) → Mykonos → Marmaris

Departs Oct 02, 2028 from Marmaris, Turkey

Up to 1 deal

Inside From

$1,189

50% Off List

List Price

$2,368

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night mediterranean cruise

Inside From

$1,190

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 02, 2028 View Other Dates →

Ports:

Marseille → Genoa → Naples → Palermo → Valletta → Barcelona → Marseille

Departs Oct 02, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,190

50% Off List

List Price

$2,368

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,400

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 02, 2028 View Other Dates →

Ports:

Naples → Messina → Valletta → Barcelona → Marseille → Genoa → Naples

Departs Oct 02, 2028 from Naples, Italy

Up to 2 deals

Inside From

$1,400

50% Off List

List Price

$2,788

View Expanded Details

MSC Cruises MSC Seaview itinerary map

9-night mediterranean cruise

Inside From

$1,584

49% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Oct 02, 2028 View Other Dates →

Ports:

Bari → Trieste → Split → Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari

Departs Oct 02, 2028 from Bari, Italy

Up to 2 deals

Inside From

$1,584

49% Off List

List Price

$3,098

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,636

49% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Oct 03, 2028 View Other Dates →

Ports:

Marseille → Malaga → Cadiz → Lisbon → Alicante → Mahon → Olbia → Genoa → Marseille

Departs Oct 03, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,636

49% Off List

List Price

$3,229

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night mediterranean cruise

Inside From

$1,190

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 04, 2028 View Other Dates →

Ports:

Naples → Palermo → Valletta → Barcelona → Marseille → Genoa → Naples

Departs Oct 04, 2028 from Naples, Italy

Up to 2 deals

Inside From

$1,190

50% Off List

List Price

$2,368

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,446

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 04, 2028 View Other Dates →

Ports:

Valletta → Barcelona → Marseille → Genoa → Naples → Messina → Valletta

Departs Oct 04, 2028 from Valletta, Malta

Up to 2 deals

Inside From

$1,446

50% Off List

List Price

$2,876

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,180

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 05, 2028 View Other Dates →

Ports:

Naples → Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples

Departs Oct 05, 2028 from Naples, Italy

Up to 1 deal

Inside From

$1,180

50% Off List

List Price

$2,348

View Expanded Details

MSC Cruises MSC Seashore itinerary map

7-night mediterranean cruise

Inside From

$1,190

50% Off List

MSC Cruises – MSC Seashore

4.125 Reviews

Date:

Oct 05, 2028 View Other Dates →

Ports:

Palermo → Valletta → Barcelona → Marseille → Genoa → Naples → Palermo

Departs Oct 05, 2028 from Palermo, Italy

Up to 2 deals

Inside From

$1,190

50% Off List

List Price

$2,368

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,641

49% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Oct 05, 2028 View Other Dates →

Ports:

Malaga → Cadiz → Lisbon → Alicante → Mahon → Olbia → Genoa → Marseille → Malaga

Departs Oct 05, 2028 from Malaga, Spain

Up to 2 deals

Inside From

$1,641

49% Off List

List Price

$3,234

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,641

49% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Oct 07, 2028 View Other Dates →

Ports:

Lisbon → Alicante → Mahon → Olbia → Genoa → Marseille → Malaga → Cadiz → Lisbon

Departs Oct 07, 2028 from Lisbon, Portugal

Up to 2 deals

Inside From

$1,641

49% Off List

List Price

$3,234

View Expanded Details

Showing 2601-2625 of 2,683 results

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