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MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,160

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 19, 2028 View Other Dates →

Ports:

Naples → Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples

Departs Oct 19, 2028 from Naples, Italy

Up to 1 deal

Inside From

$1,160

50% Off List

List Price

$2,308

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,159

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 20, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples → Rome (Civitavecchia)

Departs Oct 20, 2028 from Rome (Civitavecchia), Italy

Up to 1 deal

Inside From

$1,159

50% Off List

List Price

$2,308

View Expanded Details

MSC Cruises MSC Seaview itinerary map

9-night mediterranean cruise

Inside From

$1,524

49% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Oct 20, 2028 View Other Dates →

Ports:

Bari → Trieste → Split → Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari

Departs Oct 20, 2028 from Bari, Italy

Up to 2 deals

Inside From

$1,524

49% Off List

List Price

$2,978

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$960

49% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Oct 22, 2028 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs Oct 22, 2028 from Venice, Italy

Up to 2 deals

Inside From

$960

49% Off List

List Price

$1,898

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,049

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Oct 23, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia)

Departs Oct 23, 2028 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$1,049

50% Off List

List Price

$2,088

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,159

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 23, 2028 View Other Dates →

Ports:

Marmaris → Santorini → Naples → Rome (Civitavecchia) → Mykonos → Marmaris

Departs Oct 23, 2028 from Marmaris, Turkey

Up to 1 deal

Inside From

$1,159

50% Off List

List Price

$2,308

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,440

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 23, 2028 View Other Dates →

Ports:

Naples → Messina → Valletta → Barcelona → Marseille → Genoa → Naples

Departs Oct 23, 2028 from Naples, Italy

Up to 2 deals

Inside From

$1,440

50% Off List

List Price

$2,868

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,067

49% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Oct 24, 2028 View Other Dates →

Ports:

Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno

Departs Oct 24, 2028 from Livorno, Italy

Up to 2 deals

Inside From

$1,067

49% Off List

List Price

$2,107

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,436

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 25, 2028 View Other Dates →

Ports:

Valletta → Barcelona → Marseille → Genoa → Naples → Messina → Valletta

Departs Oct 25, 2028 from Valletta, Malta

Up to 2 deals

Inside From

$1,436

50% Off List

List Price

$2,856

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$819

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Oct 26, 2028

Ports:

Istanbul → Corfu → Bari → Trieste → Split → Piraeus (Athens)

Departs Oct 26, 2028 from Istanbul, Turkey

Inside From

$819

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,139

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 27, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples → Rome (Civitavecchia)

Departs Oct 27, 2028 from Rome (Civitavecchia), Italy

Up to 1 deal

Inside From

$1,139

50% Off List

List Price

$2,268

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$960

49% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Oct 29, 2028 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs Oct 29, 2028 from Venice, Italy

Up to 2 deals

Inside From

$960

49% Off List

List Price

$1,898

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,186

50% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Oct 29, 2028 View Other Dates →

Ports:

Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona → Marseille

Departs Oct 29, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,186

50% Off List

List Price

$2,356

View Expanded Details

MSC Cruises MSC Seaview itinerary map

9-night mediterranean cruise

Inside From

$1,290

50% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Oct 29, 2028

Ports:

Bari → Trieste → Split → Piraeus (Athens) → Kusadasi → Heraklion → Katakolon → Naples

Departs Oct 29, 2028 from Bari, Italy

Up to 2 deals

Inside From

$1,290

50% Off List

List Price

$2,558

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,441

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 29, 2028 View Other Dates →

Ports:

Genoa → Naples → Messina → Valletta → Barcelona → Marseille → Genoa

Departs Oct 29, 2028 from Genoa, Italy

Up to 2 deals

Inside From

$1,441

50% Off List

List Price

$2,855

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,139

50% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Oct 30, 2028 View Other Dates →

Ports:

Marmaris → Santorini → Naples → Rome (Civitavecchia) → Mykonos → Marmaris

Departs Oct 30, 2028 from Marmaris, Turkey

Up to 1 deal

Inside From

$1,139

50% Off List

List Price

$2,268

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,430

50% Off List

MSC Cruises – MSC World Asia

Date:

Oct 30, 2028 View Other Dates →

Ports:

Naples → Messina → Valletta → Barcelona → Marseille → Genoa → Naples

Departs Oct 30, 2028 from Naples, Italy

Up to 2 deals

Inside From

$1,430

50% Off List

List Price

$2,848

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,436

50% Off List

MSC Cruises – MSC World Asia

Date:

Nov 03, 2028 View Other Dates →

Ports:

Barcelona → Marseille → Genoa → Naples → Messina → Valletta → Barcelona

Departs Nov 03, 2028 from Barcelona, Spain

Up to 2 deals

Inside From

$1,436

50% Off List

List Price

$2,851

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$960

49% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Nov 05, 2028 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs Nov 05, 2028 from Venice, Italy

Up to 2 deals

Inside From

$960

49% Off List

List Price

$1,898

View Expanded Details

MSC Cruises MSC Splendida itinerary map

24-night mediterranean cruise

Oceanview From

$3,089

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

Nov 10, 2027

Ports:

Departs Nov 10, 2027 from Kusadasi, Turkey

Up to 1 deal

Oceanview From

$3,089

View Expanded Details

MSC Cruises MSC Orchestra itinerary map

7-night mediterranean cruise

Balcony From

Call Us

MSC Cruises – MSC Orchestra

4.04 Reviews

Date:

Dec 21, 2026 View Other Dates →

Ports:

Piraeus (Athens) → Izmir → Istanbul → Corfu → Bari → Piraeus (Athens)

Departs Dec 21, 2026 from Piraeus (Athens), Greece

Up to 4 deals

Balcony From

Call Us

View Expanded Details

MSC Cruises MSC Seaview itinerary map

4-night mediterranean cruise

Balcony From

Call Us

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Mar 28, 2027

Ports:

Barcelona → Marseille → Genoa → Naples → Palermo

Departs Mar 28, 2027 from Barcelona, Spain

Balcony From

Call Us

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

6-night mediterranean cruise

Balcony From

Call Us

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Apr 20, 2027

Ports:

Barcelona → La Goulette → Palermo → Naples → Livorno → Marseille

Departs Apr 20, 2027 from Barcelona, Spain

Balcony From

Call Us

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

4-night mediterranean cruise

Balcony From

Call Us

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Apr 20, 2027

Ports:

Barcelona → La Goulette → Palermo → Naples

Departs Apr 20, 2027 from Barcelona, Spain

Balcony From

Call Us

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Balcony From

Call Us

MSC Cruises – MSC Musica

3.54 Reviews

Date:

May 29, 2027 View Other Dates →

Ports:

Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille → Genoa

Departs May 29, 2027 from Genoa, Italy

Up to 3 deals

Balcony From

Call Us

View Expanded Details

Showing 2726-2750 of 2,757 results

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