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MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$905

57% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Apr 29, 2027 View Other Dates →

Ports:

Palermo → Valletta → Barcelona → Marseille → Genoa → Naples → Palermo

Departs Apr 29, 2027 from Palermo, Italy

Up to 3 deals

Inside From

$905

57% Off List

List Price

$2,128

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$1,008

59% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Apr 29, 2027 View Other Dates →

Ports:

Naples → Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples

Departs Apr 29, 2027 from Naples, Italy

Up to 3 deals

Inside From

$1,008

59% Off List

List Price

$2,448

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,106

35% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Apr 29, 2027 View Other Dates →

Ports:

Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno → Cannes → Barcelona

Departs Apr 29, 2027 from Barcelona, Spain

Up to 3 deals

Inside From

$1,106

35% Off List

List Price

$1,699

View Expanded Details

MSC Cruises MSC Sinfonia itinerary map

10-night mediterranean cruise

Inside From

$1,787

45% Off List

MSC Cruises – MSC Sinfonia

4.03 Reviews

Date:

Apr 29, 2027 View Other Dates →

Ports:

Marseille → Malaga → Tangier → Portimao → Ceuta → Alicante → Rome (Civitavecchia) → Genoa → Marseille

Departs Apr 29, 2027 from Marseille, France

Up to 3 deals

Inside From

$1,787

45% Off List

List Price

$3,249

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$864

61% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Brindisi (Lecce) Italy → Split → Venice → Dubrovnik → Corfu → Kotor

Departs Apr 30, 2027 from Brindisi

Up to 3 deals

Inside From

$864

61% Off List

List Price

$2,204

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$882

58% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Palermo → Naples → Livorno → Marseille → Barcelona → La Goulette → Palermo

Departs Apr 30, 2027 from Palermo, Italy

Up to 3 deals

Inside From

$882

58% Off List

List Price

$2,108

View Expanded Details

MSC Cruises MSC Divina itinerary map

7-night mediterranean cruise

Inside From

$917

63% Off List

MSC Cruises – MSC Divina

3.892 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Rome (Civitavecchia) → Mykonos → Marmaris → Santorini → Naples → Rome (Civitavecchia)

Departs Apr 30, 2027 from Rome (Civitavecchia), Italy

Up to 3 deals

Inside From

$917

63% Off List

List Price

$2,446

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,044

58% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Palma de Mallorca → Barcelona → Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca

Departs Apr 30, 2027 from Palma de Mallorca, Spain

Up to 3 deals

Inside From

$1,044

58% Off List

List Price

$2,492

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,176

45% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Valletta → Barcelona → Marseille → Genoa → Naples → Palermo → Valletta

Departs Apr 30, 2027 from Valletta, Malta

Up to 3 deals

Inside From

$1,176

45% Off List

List Price

$2,136

View Expanded Details

MSC Cruises MSC Splendida itinerary map

9-night mediterranean cruise

Inside From

$1,358

57% Off List

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

Apr 30, 2027 View Other Dates →

Ports:

Bari → Trieste → Split → Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari

Departs Apr 30, 2027 from Bari, Italy

Up to 3 deals

Inside From

$1,358

57% Off List

List Price

$3,150

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$932

58% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

May 01, 2027 View Other Dates →

Ports:

Split → Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split

Departs May 01, 2027 from Split, Croatia

Up to 3 deals

Inside From

$932

58% Off List

List Price

$2,203

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,065

57% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

May 01, 2027 View Other Dates →

Ports:

Barcelona → Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona

Departs May 01, 2027 from Barcelona, Spain

Up to 3 deals

Inside From

$1,065

57% Off List

List Price

$2,491

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,305

51% Off List

MSC Cruises – MSC World Asia

Date:

May 01, 2027 View Other Dates →

Ports:

Marseille → Genoa → Naples → Messina → Valletta → Barcelona → Marseille

Departs May 01, 2027 from Marseille, France

Up to 2 deals

Inside From

$1,305

51% Off List

List Price

$2,648

View Expanded Details

MSC Cruises MSC Splendida itinerary map

9-night mediterranean cruise

Inside From

$1,567

49% Off List

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

May 01, 2027 View Other Dates →

Ports:

Trieste → Split → Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari → Trieste

Departs May 01, 2027 from Trieste, Italy

Up to 3 deals

Inside From

$1,567

49% Off List

List Price

$3,070

View Expanded Details

MSC Cruises MSC Armonia itinerary map

7-night mediterranean cruise

Inside From

$1,024

53% Off List

MSC Cruises – MSC Armonia

3.219 Reviews

Date:

May 02, 2027 View Other Dates →

Ports:

Venice → Dubrovnik → Corfu → Kotor → Brindisi (Lecce) Italy → Split → Venice

Departs May 02, 2027 from Venice, Italy

Up to 3 deals

Inside From

$1,024

53% Off List

List Price

$2,200

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,143

35% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

May 02, 2027 View Other Dates →

Ports:

Cagliari → Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari

Departs May 02, 2027 from Cagliari, Sardinia, Italy

Up to 2 deals

Inside From

$1,143

35% Off List

List Price

$1,772

View Expanded Details

MSC Cruises MSC World Europa itinerary map

7-night mediterranean cruise

Inside From

$1,263

49% Off List

MSC Cruises – MSC World Europa

2.03 Reviews

Date:

May 02, 2027 View Other Dates →

Ports:

Marseille → Genoa → Florence (La Spezia) → Rome (Civitavecchia) → Palma de Mallorca → Barcelona → Marseille

Departs May 02, 2027 from Marseille, France

Up to 3 deals

Inside From

$1,263

49% Off List

List Price

$2,496

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,330

50% Off List

MSC Cruises – MSC World Asia

Date:

May 02, 2027 View Other Dates →

Ports:

Genoa → Naples → Messina → Valletta → Barcelona → Marseille → Genoa

Departs May 02, 2027 from Genoa, Italy

Up to 2 deals

Inside From

$1,330

50% Off List

List Price

$2,655

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$836

52% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

May 03, 2027 View Other Dates →

Ports:

Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia)

Departs May 03, 2027 from Rome (Civitavecchia), Italy

Up to 3 deals

Inside From

$836

52% Off List

List Price

$1,746

View Expanded Details

MSC Cruises MSC Virtuosa itinerary map

7-night mediterranean cruise

Inside From

$896

57% Off List

MSC Cruises – MSC Virtuosa

5.01 Reviews

Date:

May 04, 2027 View Other Dates →

Ports:

Barcelona → La Goulette → Palermo → Naples → Livorno → Marseille → Barcelona

Departs May 04, 2027 from Barcelona, Spain

Up to 3 deals

Inside From

$896

57% Off List

List Price

$2,091

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,030

50% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

May 04, 2027 View Other Dates →

Ports:

Genoa → Naples → Palermo → Valletta → Barcelona → Marseille → Genoa

Departs May 04, 2027 from Genoa, Italy

Up to 3 deals

Inside From

$1,030

50% Off List

List Price

$2,076

View Expanded Details

MSC Cruises MSC World Asia itinerary map

7-night mediterranean cruise

Inside From

$1,078

57% Off List

MSC Cruises – MSC World Asia

Date:

May 04, 2027 View Other Dates →

Ports:

Messina → Valletta → Barcelona → Marseille → Genoa → Naples → Messina

Departs May 04, 2027 from Messina, Italy

Up to 2 deals

Inside From

$1,078

57% Off List

List Price

$2,496

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,119

37% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

May 04, 2027 View Other Dates →

Ports:

Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno

Departs May 04, 2027 from Livorno, Italy

Up to 3 deals

Inside From

$1,119

37% Off List

List Price

$1,785

View Expanded Details

MSC Cruises MSC Splendida itinerary map

9-night mediterranean cruise

Inside From

$1,433

54% Off List

MSC Cruises – MSC Splendida

4.79 Reviews

Date:

May 04, 2027 View Other Dates →

Ports:

Piraeus (Athens) → Kusadasi → Istanbul → Corfu → Bari → Trieste → Split → Piraeus (Athens)

Departs May 04, 2027 from Piraeus (Athens), Greece

Up to 3 deals

Inside From

$1,433

54% Off List

List Price

$3,102

View Expanded Details

MSC Cruises MSC Seaview itinerary map

7-night mediterranean cruise

Inside From

$1,033

51% Off List

MSC Cruises – MSC Seaview

4.65 Reviews

Date:

May 05, 2027 View Other Dates →

Ports:

Naples → Palermo → Valletta → Barcelona → Marseille → Genoa → Naples

Departs May 05, 2027 from Naples, Italy

Up to 3 deals

Inside From

$1,033

51% Off List

List Price

$2,108

View Expanded Details

Showing 926-950 of 2,757 results

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