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MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,164

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 20, 2028 View Other Dates →

Ports:

Valencia → Marseille → Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia

Departs Jul 20, 2028 from Valencia, Spain

Up to 2 deals

Inside From

$1,164

50% Off List

List Price

$2,313

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,171

50% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 20, 2028 View Other Dates →

Ports:

Marseille → Barcelona (Tarragona) → Valencia → Florence (La Spezia) → Rome (Civitavecchia) → Genoa → Marseille

Departs Jul 20, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,171

50% Off List

List Price

$2,330

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,161

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 21, 2028 View Other Dates →

Ports:

Marseille → Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille

Departs Jul 21, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,161

50% Off List

List Price

$2,310

View Expanded Details

MSC Cruises MSC Lirica itinerary map

7-night mediterranean cruise

Inside From

$1,169

48% Off List

MSC Cruises – MSC Lirica

4.36 Reviews

Date:

Jul 21, 2028 View Other Dates →

Ports:

Ancona → Venice → Kotor → Mykonos → Syros Greece → Ancona

Departs Jul 21, 2028 from Ancona, Italy

Up to 2 deals

Inside From

$1,169

48% Off List

List Price

$2,261

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,259

48% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 21, 2028 View Other Dates →

Ports:

Departs Jul 21, 2028 from Barcelona (Tarragona), Spain

Up to 2 deals

Inside From

$1,259

48% Off List

List Price

$2,418

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,174

50% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 22, 2028 View Other Dates →

Ports:

Valencia → Florence (La Spezia) → Rome (Civitavecchia) → Genoa → Marseille → Barcelona (Tarragona) → Valencia

Departs Jul 22, 2028 from Valencia, Spain

Up to 2 deals

Inside From

$1,174

50% Off List

List Price

$2,333

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,176

49% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 22, 2028 View Other Dates →

Ports:

Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille → Genoa

Departs Jul 22, 2028 from Genoa, Italy

Up to 2 deals

Inside From

$1,176

49% Off List

List Price

$2,325

View Expanded Details

MSC Cruises MSC Lirica itinerary map

7-night mediterranean cruise

Inside From

$1,195

48% Off List

MSC Cruises – MSC Lirica

4.36 Reviews

Date:

Jul 22, 2028 View Other Dates →

Ports:

Venice → Kotor → Mykonos → Syros Greece → Ancona → Venice

Departs Jul 22, 2028 from Venice, Italy

Up to 2 deals

Inside From

$1,195

48% Off List

List Price

$2,287

View Expanded Details

MSC Cruises MSC Orchestra itinerary map

7-night mediterranean cruise

Inside From

$1,208

50% Off List

MSC Cruises – MSC Orchestra

4.04 Reviews

Date:

Jul 22, 2028 View Other Dates →

Ports:

Bari → Santorini → Piraeus (Athens) → Katakolon → Cefalonia/Argostoli Greece → Corfu → Bari

Departs Jul 22, 2028 from Bari, Italy

Up to 2 deals

Inside From

$1,208

50% Off List

List Price

$2,397

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,161

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 23, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille → Genoa → Rome (Civitavecchia)

Departs Jul 23, 2028 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$1,161

50% Off List

List Price

$2,310

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,364

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jul 23, 2028 View Other Dates →

Ports:

Cagliari → Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari

Departs Jul 23, 2028 from Cagliari, Sardinia, Italy

Up to 2 deals

Inside From

$1,364

50% Off List

List Price

$2,714

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,240

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 24, 2028 View Other Dates →

Ports:

Palermo → Ibiza → Valencia → Marseille → Genoa → Rome (Civitavecchia) → Palermo

Departs Jul 24, 2028 from Palermo, Italy

Up to 2 deals

Inside From

$1,240

50% Off List

List Price

$2,468

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,359

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jul 24, 2028 View Other Dates →

Ports:

Rome (Civitavecchia) → Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia)

Departs Jul 24, 2028 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$1,359

50% Off List

List Price

$2,708

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,169

50% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 25, 2028 View Other Dates →

Ports:

Departs Jul 25, 2028 from Rome (Civitavecchia), Italy

Up to 2 deals

Inside From

$1,169

50% Off List

List Price

$2,328

View Expanded Details

MSC Cruises MSC Orchestra itinerary map

7-night mediterranean cruise

Inside From

$1,207

50% Off List

MSC Cruises – MSC Orchestra

4.04 Reviews

Date:

Jul 25, 2028 View Other Dates →

Ports:

Piraeus (Athens) → Katakolon → Cefalonia/Argostoli Greece → Corfu → Bari → Santorini → Piraeus (Athens)

Departs Jul 25, 2028 from Piraeus (Athens), Greece

Up to 2 deals

Inside From

$1,207

50% Off List

List Price

$2,396

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,377

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jul 25, 2028 View Other Dates →

Ports:

Livorno → Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno

Departs Jul 25, 2028 from Livorno, Italy

Up to 2 deals

Inside From

$1,377

50% Off List

List Price

$2,727

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,276

49% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 26, 2028 View Other Dates →

Ports:

Genoa → Marseille → Barcelona (Tarragona) → Valencia → Florence (La Spezia) → Rome (Civitavecchia) → Genoa

Departs Jul 26, 2028 from Genoa, Italy

Up to 2 deals

Inside From

$1,276

49% Off List

List Price

$2,525

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,392

49% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jul 26, 2028 View Other Dates →

Ports:

Cannes → Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno → Cannes

Departs Jul 26, 2028 from Cannes, France

Up to 2 deals

Inside From

$1,392

49% Off List

List Price

$2,735

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,261

50% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 27, 2028 View Other Dates →

Ports:

Marseille → Barcelona (Tarragona) → Valencia → Florence (La Spezia) → Rome (Civitavecchia) → Genoa → Marseille

Departs Jul 27, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,261

50% Off List

List Price

$2,510

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,264

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 27, 2028 View Other Dates →

Ports:

Valencia → Marseille → Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia

Departs Jul 27, 2028 from Valencia, Spain

Up to 2 deals

Inside From

$1,264

50% Off List

List Price

$2,513

View Expanded Details

MSC Cruises MSC Fantasia itinerary map

7-night mediterranean cruise

Inside From

$1,366

50% Off List

MSC Cruises – MSC Fantasia

3.812 Reviews

Date:

Jul 27, 2028 View Other Dates →

Ports:

Barcelona → Ibiza → Cagliari → Rome (Civitavecchia) → Livorno → Cannes → Barcelona

Departs Jul 27, 2028 from Barcelona, Spain

Up to 2 deals

Inside From

$1,366

50% Off List

List Price

$2,711

View Expanded Details

MSC Cruises MSC Lirica itinerary map

7-night mediterranean cruise

Inside From

$1,259

48% Off List

MSC Cruises – MSC Lirica

4.36 Reviews

Date:

Jul 28, 2028 View Other Dates →

Ports:

Ancona → Venice → Kotor → Mykonos → Syros Greece → Ancona

Departs Jul 28, 2028 from Ancona, Italy

Up to 2 deals

Inside From

$1,259

48% Off List

List Price

$2,441

View Expanded Details

MSC Cruises MSC Musica itinerary map

7-night mediterranean cruise

Inside From

$1,261

50% Off List

MSC Cruises – MSC Musica

3.54 Reviews

Date:

Jul 28, 2028 View Other Dates →

Ports:

Marseille → Genoa → Rome (Civitavecchia) → Palermo → Ibiza → Valencia → Marseille

Departs Jul 28, 2028 from Marseille, France

Up to 2 deals

Inside From

$1,261

50% Off List

List Price

$2,510

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,349

48% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 28, 2028 View Other Dates →

Ports:

Departs Jul 28, 2028 from Barcelona (Tarragona), Spain

Up to 2 deals

Inside From

$1,349

48% Off List

List Price

$2,598

View Expanded Details

MSC Cruises MSC Magnifica itinerary map

7-night mediterranean cruise

Inside From

$1,264

50% Off List

MSC Cruises – MSC Magnifica

4.313 Reviews

Date:

Jul 29, 2028 View Other Dates →

Ports:

Valencia → Florence (La Spezia) → Rome (Civitavecchia) → Genoa → Marseille → Barcelona (Tarragona) → Valencia

Departs Jul 29, 2028 from Valencia, Spain

Up to 2 deals

Inside From

$1,264

50% Off List

List Price

$2,513

View Expanded Details

Showing 1676-1700 of 2,690 results

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