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No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. Plus, our Low Price Guarantee! No Avoya Fees on Cruises or Tours.
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MSC Cruises to South America
MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.
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7-night south america cruise
$1,349
50% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 07, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,546
49% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 07, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,389
49% Off List
MSC Cruises –
MSC Preziosa
Departs
Feb 08, 2026
from
Santos, Brazil
Up to 3 deals
3-night south america cruise
$790
49% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 10, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,169
60% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 10, 2026
from
Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,309
49% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 10, 2026
from
MACEIO
Up to 3 deals
7-night south america cruise
$1,550
49% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 11, 2026
from
Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,704
50% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 11, 2026
from
MACEIO
Up to 2 deals
4-night south america cruise
$817
49% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 13, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,238
49% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 14, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,483
50% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 14, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,585
50% Off List
MSC Cruises –
MSC Preziosa
Departs
Feb 15, 2026
from
Santos, Brazil
Up to 3 deals
9-night south america cruise
$2,651
49% Off List
MSC Cruises –
MSC Fantasia
Departs
Feb 16, 2026
from
Montevideo, Uruguay
Up to 3 deals
3-night south america cruise
$743
49% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 17, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,250
42% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 17, 2026
from
Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,453
MSC Cruises –
MSC Armonia
Departs
Feb 17, 2026
from
MACEIO
Up to 1 deal
7-night south america cruise
$1,205
54% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 18, 2026
from
Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,515
50% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 18, 2026
from
MACEIO
Up to 2 deals
4-night south america cruise
$909
49% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 20, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,049
49% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 21, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,071
51% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 21, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,139
49% Off List
MSC Cruises –
MSC Preziosa
Departs
Feb 22, 2026
from
Santos, Brazil
Up to 3 deals
3-night south america cruise
$691
50% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 24, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,101
50% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 24, 2026
from
Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,132
50% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 25, 2026
from
MACEIO
Up to 2 deals