Menu
Call
No Avoya Fees on Cruises or Tours. Learn More
Home
cruises to south america

MSC Cruises to South America

MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.

Showing 1-25 of 195 results
25-Night South America Cruise
$1,099
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 08, 2022 from Istanbul, Turkey
Up to 1 deal and Avoya Exclusives
24-Night South America Cruise
$889
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 08, 2022 from Istanbul, Turkey
Up to 1 deal and Avoya Exclusives
19-Night South America Cruise
$439
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 13, 2022 from Trieste, Italy
Up to 1 deal and Avoya Exclusives
20-Night South America Cruise
$499
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 13, 2022 from Trieste, Italy
Up to 1 deal and Avoya Exclusives
16-Night South America Cruise
$439
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 13, 2022 from Trieste, Italy
Up to 1 deal and Avoya Exclusives
18-Night South America Cruise
$439
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 15, 2022 from Messina, Italy
Up to 1 deal and Avoya Exclusives
16-Night South America Cruise
$399
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 17, 2022 from Rome (Civitavecchia), Italy
Up to 1 deal and Avoya Exclusives
15-Night South America Cruise
$429
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 17, 2022 from Rome (Civitavecchia), Italy
Up to 1 deal and Avoya Exclusives
15-Night South America Cruise
$349
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 18, 2022 from Marseille, France
Up to 1 deal and Avoya Exclusives
14-Night South America Cruise
$329
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 18, 2022 from Marseille, France
Up to 1 deal and Avoya Exclusives
13-Night South America Cruise
$299
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 19, 2022 from Barcelona, Spain
Up to 1 deal and Avoya Exclusives
14-Night South America Cruise
$389
50% Off List
MSC Cruises – MSC Fantasia
8 Reviews
Depart Oct 19, 2022 from Barcelona, Spain
Up to 1 deal and Avoya Exclusives
Roundtrip
3-Night South America Cruise
$319
MSC Cruises – MSC Fantasia
8 Reviews
Depart Nov 02, 2022 from Santos, Brazil
Roundtrip
4-Night South America Cruise
$389
MSC Cruises – MSC Fantasia
8 Reviews
Depart Nov 08, 2022 from Santos, Brazil
21-Night South America Cruise
$769
61% Off List
MSC Cruises – MSC Musica
4 Reviews
Depart Nov 13, 2022 from
Up to 2 deals and Avoya Exclusives
Roundtrip
3-Night South America Cruise
$319
MSC Cruises – MSC Fantasia
8 Reviews
Depart Nov 15, 2022 from Santos, Brazil
Up to 1 deal and Avoya Exclusives
15-Night South America Cruise
$629
49% Off List
MSC Cruises – MSC Seaview
3 Reviews
Depart Nov 18, 2022 from Genoa, Italy
Up to 2 deals and Avoya Exclusives
18-Night South America Cruise
$879
50% Off List
MSC Cruises – MSC Seaview
3 Reviews
Depart Nov 18, 2022 from Genoa, Italy
Up to 2 deals and Avoya Exclusives
17-Night South America Cruise
$659
52% Off List
MSC Cruises – MSC Seaview
3 Reviews
Depart Nov 19, 2022 from Marseille, France
Up to 2 deals and Avoya Exclusives
16-Night South America Cruise
$649
50% Off List
MSC Cruises – MSC Seaview
3 Reviews
Depart Nov 20, 2022 from Barcelona, Spain
Up to 2 deals and Avoya Exclusives
17-Night South America Cruise
$699
MSC Cruises – MSC Armonia
18 Reviews
Depart Nov 20, 2022 from Venice, Italy
Up to 2 deals and Avoya Exclusives
15-Night South America Cruise
$659
MSC Cruises – MSC Armonia
18 Reviews
Depart Nov 20, 2022 from Venice, Italy
Up to 2 deals and Avoya Exclusives
18-Night South America Cruise
$850
MSC Cruises – MSC Armonia
18 Reviews
Depart Nov 20, 2022 from Venice, Italy
Up to 2 deals and Avoya Exclusives
20-Night South America Cruise
$1,009
56% Off List
MSC Cruises – MSC Seashore
4 Reviews
Depart Nov 20, 2022 from Miami, Florida
Up to 2 deals and Avoya Exclusives
19-Night South America Cruise
$1,130
MSC Cruises – MSC Seashore
4 Reviews
Depart Nov 20, 2022 from Miami, Florida
Up to 2 deals and Avoya Exclusives
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. …8
  7. Next
Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Logo
Why Choose Avoya?
U.S. / Canada: 1-888-877-7042
UK: 0-800-098-8475
Australia: 1-800-651-320
International: 001-760-305-5070
Avoya Travel®
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Amex Logo
Avoya Travel® is an American Express Travel Representative.