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Princess Cruises to Panama Canal

Princess Cruises Panama Canal vacations offer an unforgettable experience exploring dramatic landscapes and sailing through one of the most remarkable man-made wonders in the world. Guests will travel one of the most vital trade routes in existence on a Princess Panama Canal cruise, and will enjoy all of the activity, sights, and sounds surrounding this destination. Princess Cruises to the Panama Canal feature onboard comforts in well-appointed accommodations as well as several delicious dining options and many choices for onboard entertainment. Princess Cruise Line Panama Cruises are a must for travelers seeking a tropical sunny escape rich with history and culture.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Oceanview From

$1,269

32% Off

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Dec 29, 2026 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Grand Cayman → Fort Lauderdale

Departs Dec 29, 2026 from Fort Lauderdale, Florida

Up to 5 deals including Avoya Exclusives

Secret Rate

Avoya Exclusive Rate

Oceanview From

$1,269

32% Off

Compare At

$2,226

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,124

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Feb 15, 2027 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Grand Cayman → Fort Lauderdale

Departs Feb 15, 2027 from Fort Lauderdale, Florida

Up to 6 deals including Avoya Exclusives

Secret Rate

Avoya Exclusive Rate

Inside From

$1,124

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Inside From

$1,399

16% Off

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Apr 03, 2027 View Other Dates →

Ports:

Departs Apr 03, 2027 from Los Angeles, California

Up to 5 deals including an Avoya Exclusive

Secret Rate

Avoya Exclusive Rate

Inside From

$1,399

16% Off

Compare At

$1,659

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$899

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Dec 05, 2026

Ports:

Fort Lauderdale → Grand Cayman → Falmouth → Cartagena → Colon → Puerto Limon → Celebration Key → Fort Lauderdale

Departs Dec 05, 2026 from Fort Lauderdale, Florida

Up to 5 deals including Avoya Exclusives

Secret Rate

Avoya Exclusive Rate

Inside From

$899

View Expanded Details

Princess Cruises Coral Princess itinerary map

16-night panama canal cruise

Inside From

$949

Princess Cruises – Coral Princess

4.4127 Reviews

Date:

Sep 29, 2026

Ports:

Departs Sep 29, 2026 from Los Angeles, California

Up to 3 deals including an Avoya Exclusive

Secret Rate

Inside From

$949

View Expanded Details

Princess Cruises Star Princess itinerary map

16-night panama canal cruise

Inside From

$1,359

Princess Cruises – Star Princess

5.01 Reviews

Date:

Oct 04, 2026

Ports:

Departs Oct 04, 2026 from Los Angeles, California

Up to 4 deals including an Avoya Exclusive

Secret Rate

Inside From

$1,359

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$919

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Oct 30, 2026 View Other Dates →

Ports:

Fort Lauderdale → Curacao → Cartagena → Colon → Puerto Limon → Celebration Key → Fort Lauderdale

Departs Oct 30, 2026 from Fort Lauderdale, Florida

Up to 3 deals including an Avoya Exclusive

Secret Rate

Inside From

$919

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$899

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Nov 23, 2026 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Celebration Key → Fort Lauderdale

Departs Nov 23, 2026 from Fort Lauderdale, Florida

Up to 4 deals including an Avoya Exclusive

Secret Rate

Inside From

$899

View Expanded Details

Princess Cruises Crown Princess itinerary map

16-night panama canal cruise

Inside From

$1,209

Princess Cruises – Crown Princess

4.3211 Reviews

Date:

Dec 03, 2026

Ports:

Departs Dec 03, 2026 from Los Angeles, California

Up to 4 deals including an Avoya Exclusive

Secret Rate

Inside From

$1,209

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$1,359

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Dec 12, 2026

Ports:

Departs Dec 12, 2026 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Oceanview From

$1,359

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,072

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Dec 17, 2026 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Grand Cayman → Fort Lauderdale

Departs Dec 17, 2026 from Fort Lauderdale, Florida

Up to 4 deals including an Avoya Exclusive

Secret Rate

Inside From

$1,072

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$2,249

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Dec 28, 2026

Ports:

Departs Dec 28, 2026 from Los Angeles, California

Up to 5 deals including an Avoya Exclusive

Secret Rate

Oceanview From

$2,249

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,049

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Jan 10, 2027 View Other Dates →

Ports:

Fort Lauderdale → Curacao → Cartagena → Colon → Puerto Limon → Celebration Key → Fort Lauderdale

Departs Jan 10, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Inside From

$1,049

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$2,409

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Jan 13, 2027

Ports:

Departs Jan 13, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Avoya Exclusive Rate

Oceanview From

$2,409

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,119

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Jan 22, 2027 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Celebration Key → Fort Lauderdale

Departs Jan 22, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Avoya Exclusive Rate

Inside From

$1,119

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,234

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Feb 03, 2027 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Grand Cayman → Fort Lauderdale

Departs Feb 03, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Inside From

$1,234

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$2,489

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Feb 14, 2027 View Other Dates →

Ports:

Departs Feb 14, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Oceanview From

$2,489

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$1,989

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Mar 02, 2027 View Other Dates →

Ports:

Departs Mar 02, 2027 from Los Angeles, California

Up to 5 deals including an Avoya Exclusive

Secret Rate

Oceanview From

$1,989

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Inside From

$1,349

38% Off

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Mar 18, 2027

Ports:

Departs Mar 18, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Avoya Exclusive Rate

Inside From

$1,349

38% Off

Compare At

$2,167

View Expanded Details

Princess Cruises Star Princess itinerary map

16-night panama canal cruise

Inside From

$1,679

1% Off

Princess Cruises – Star Princess

5.01 Reviews

Date:

Apr 03, 2027

Ports:

Departs Apr 03, 2027 from Fort Lauderdale, Florida

Up to 6 deals including Avoya Exclusives

Secret Rate

Avoya Exclusive Rate

Inside From

$1,679

1% Off

Compare At

$1,719

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Oceanview From

$1,559

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Apr 19, 2027 View Other Dates →

Ports:

Departs Apr 19, 2027 from Fort Lauderdale, Florida

Up to 5 deals including an Avoya Exclusive

Secret Rate

Oceanview From

$1,559

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Inside From

$1,624

40% Off

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Jan 14, 2028 View Other Dates →

Ports:

Departs Jan 14, 2028 from Fort Lauderdale, Florida

Up to 5 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,624

40% Off

Compare At

$3,023

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Inside From

$1,524

33% Off

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Jan 30, 2028 View Other Dates →

Ports:

Departs Jan 30, 2028 from Los Angeles, California

Up to 5 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,524

33% Off

Compare At

$2,773

View Expanded Details

Princess Cruises Caribbean Princess itinerary map

12-night panama canal cruise

Inside From

$1,600

2% Off

Princess Cruises – Caribbean Princess

4.1257 Reviews

Date:

Feb 12, 2028 View Other Dates →

Ports:

Fort Lauderdale → Oranjestad → Cartagena → Colon → Puerto Limon → Grand Cayman → Cozumel → Fort Lauderdale

Departs Feb 12, 2028 from Fort Lauderdale, Florida

Up to 5 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,600

2% Off

Compare At

$1,629

View Expanded Details

Princess Cruises Island Princess itinerary map

16-night panama canal cruise

Inside From

$1,524

36% Off

Princess Cruises – Island Princess

4.2157 Reviews

Date:

Feb 15, 2028 View Other Dates →

Ports:

Departs Feb 15, 2028 from Fort Lauderdale, Florida

Up to 5 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$1,524

36% Off

Compare At

$2,823

View Expanded Details

Showing 1-25 of 47 results

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