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Home
cruises
regent cruises
cruises to mediterranean
Regent Cruises to Mediterranean
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Departure Port
Alexandria, Egypt
Barcelona, Spain
Istanbul, Turkey
Lisbon, Portugal
Monte Carlo, Monaco
Piraeus (Athens), Greece
Rome (Civitavecchia), Italy
Valletta, Malta
Venice, Italy
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Arrival Port
Alexandria, Egypt
Barcelona, Spain
Istanbul, Turkey
Lisbon, Portugal
Monte Carlo, Monaco
Piraeus (Athens), Greece
Rome (Civitavecchia), Italy
Valletta, Malta
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Cruise Ship
Regent Cruises
Seven Seas Grandeur
Seven Seas Mariner
Seven Seas Navigator
Seven Seas Splendor
Seven Seas Voyager
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Trip Length
3–6 Nights
7-9 Nights
10-14 Nights
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Cabin Type
inside or better
oceanview or better
balcony or better
suite
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12-Night Mediterranean Cruise
$8,999
63% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Sep 24, 2025
Ports:
Barcelona → Toulon → Saint Tropez → La Spezia (Cinque Terre) → Rome (Civitavecchia) → Naples → Messina → Corfu → Dubrovnik → Kotor → Piraeus (Athens)
Barcelona → Toulon → Saint Tropez → La Spezia (Cinque Terre) → Rome (Civitavecchia) → Naples → Messina → Corfu → Dubrovnik → Kotor → Piraeus (Athens)
Departs
Sep 24, 2025
from
Barcelona, Spain
Up to 8 deal
s
including an Avoya Exclusive
From
$8,999
63% Off List
List Price
$24,198
Get Availability
More Details
Top Picks Rank:
7
Save
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10-Night Mediterranean Cruise
$9,849
61% Off List
Regent Cruises – Seven Seas Grandeur
5.0
(3)
5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
View more
Date:
Sep 25, 2025
Ports:
Barcelona → Toulon → Livorno → Rome (Civitavecchia) → Sorrento → Valletta → Argostoli (Cephalonia) → Gythion → Mykonos → Piraeus (Athens)
Barcelona → Toulon → Livorno → Rome (Civitavecchia) → Sorrento → Valletta → Argostoli (Cephalonia) → Gythion → Mykonos → Piraeus (Athens)
Departs
Sep 25, 2025
from
Barcelona, Spain
Up to 6 deal
s
including an Avoya Exclusive
From
$9,849
61% Off List
List Price
$24,998
Get Availability
More Details
Top Picks Rank:
7
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14-Night Mediterranean Cruise
$9,599
62% Off List
Regent Cruises – Seven Seas Navigator
4.3
(71)
5 Star
65%
4 Star
17%
3 Star
7%
2 Star
6%
1 Star
6%
View more
Date:
Oct 05, 2025
Ports:
Piraeus (Athens) → Gythion → Igoumenitsa → Kotor → Bari → Dubrovnik → Koper → Venice → Urbino (Ancona) → Argostoli (Cephalonia) → Santorini → Mykonos → Bozcaada → Istanbul
Piraeus (Athens) → Gythion → Igoumenitsa → Kotor → Bari → Dubrovnik → Koper → Venice → Urbino (Ancona) → Argostoli (Cephalonia) → Santorini → Mykonos → Bozcaada → Istanbul
Departs
Oct 05, 2025
from
Piraeus (Athens), Greece
Up to 8 deal
s
including an Avoya Exclusive
From
$9,599
62% Off List
List Price
$25,198
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
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11-Night Mediterranean Cruise
$8,299
65% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Oct 06, 2025
Ports:
Piraeus (Athens) → Santorini → Rhodes → Alanya → Limassol → Kos → Aghios Nikolaos (Crete) → Bodrum → Kusadasi → Dikili → Istanbul
Piraeus (Athens) → Santorini → Rhodes → Alanya → Limassol → Kos → Aghios Nikolaos (Crete) → Bodrum → Kusadasi → Dikili → Istanbul
Departs
Oct 06, 2025
from
Piraeus (Athens), Greece
Up to 8 deal
s
including an Avoya Exclusive
From
$8,299
65% Off List
List Price
$23,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
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9-Night Mediterranean Cruise
$7,399
67% Off List
Regent Cruises – Seven Seas Mariner
4.5
(103)
5 Star
71%
4 Star
16%
3 Star
11%
2 Star
1%
1 Star
2%
View more
Date:
Oct 13, 2025
Ports:
Istanbul → Kusadasi → Mykonos → Katakolon → Corfu → Kotor → Split → Zadar → Venice
Departs
Oct 13, 2025
from
Istanbul, Turkey
Up to 8 deal
s
including an Avoya Exclusive
From
$7,399
67% Off List
List Price
$22,198
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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10-Night Mediterranean Cruise
$6,899
64% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Nov 29, 2025
Ports:
Barcelona → Cadiz → Funchal → Santa Cruz De La Palma → Las Palmas De Gran Canaria → Arrecife → Portimao → Lisbon
Departs
Nov 29, 2025
from
Barcelona, Spain
Up to 4 deal
s
including an Avoya Exclusive
From
$6,899
64% Off List
List Price
$19,198
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
10-Night Mediterranean Cruise
$6,999
66% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Dec 09, 2025
Ports:
Lisbon → Santa Cruz De La Palma → San Sebastian De La Gomera → Santa Cruz De Tenerife → Agadir → Casablanca → Gibraltar → Malaga → Barcelona
Lisbon → Santa Cruz De La Palma → San Sebastian De La Gomera → Santa Cruz De Tenerife → Agadir → Casablanca → Gibraltar → Malaga → Barcelona
Departs
Dec 09, 2025
from
Lisbon, Portugal
Up to 4 deal
s
including an Avoya Exclusive
From
$6,999
66% Off List
List Price
$20,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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Roundtrip
10-Night Mediterranean Cruise
$6,999
64% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Mar 23, 2026
Ports:
Lisbon → Funchal → Santa Cruz De La Palma → Santa Cruz De Tenerife → Las Palmas De Gran Canaria → Arrecife → Agadir → Casablanca → Lisbon
Lisbon → Funchal → Santa Cruz De La Palma → Santa Cruz De Tenerife → Las Palmas De Gran Canaria → Arrecife → Agadir → Casablanca → Lisbon
Departs
Mar 23, 2026
from
Lisbon, Portugal
Up to 5 deal
s
including an Avoya Exclusive
From
$6,999
64% Off List
List Price
$19,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
8-Night Mediterranean Cruise
$5,499
65% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Apr 02, 2026
Ports:
Lisbon → Cadiz → Tangier → Malaga → Cartagena → Ibiza → Palma De Mallorca → Barcelona
Departs
Apr 02, 2026
from
Lisbon, Portugal
Up to 3 deal
s
including an Avoya Exclusive
From
$5,499
65% Off List
List Price
$15,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
9-Night Mediterranean Cruise
$5,699
64% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
Apr 10, 2026
Ports:
Barcelona → Mahon → Marseille → Monte Carlo → La Spezia (Cinque Terre) → Ajaccio → Palermo → Sorrento → Rome (Civitavecchia)
Barcelona → Mahon → Marseille → Monte Carlo → La Spezia (Cinque Terre) → Ajaccio → Palermo → Sorrento → Rome (Civitavecchia)
Departs
Apr 10, 2026
from
Barcelona, Spain
Up to 3 deal
s
including an Avoya Exclusive
From
$5,699
64% Off List
List Price
$15,998
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
9-Night Mediterranean Cruise
$6,399
63% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Apr 17, 2026
Ports:
Rome (Civitavecchia) → Portoferraio → La Spezia (Cinque Terre) → Nice (Villefranche) → Alicante → Valencia → Ibiza → Barcelona
Rome (Civitavecchia) → Portoferraio → La Spezia (Cinque Terre) → Nice (Villefranche) → Alicante → Valencia → Ibiza → Barcelona
Departs
Apr 17, 2026
from
Rome (Civitavecchia), Italy
Up to 3 deal
s
including an Avoya Exclusive
From
$6,399
63% Off List
List Price
$17,398
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
13-Night Mediterranean Cruise
$7,999
63% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
Apr 19, 2026
Ports:
Rome (Civitavecchia) → Amalfi → Trapani → La Goulette → Valletta → Argostoli (Cephalonia) → Brindisi → Kotor → Dubrovnik → Split → Koper → Venice
Rome (Civitavecchia) → Amalfi → Trapani → La Goulette → Valletta → Argostoli (Cephalonia) → Brindisi → Kotor → Dubrovnik → Split → Koper → Venice
Departs
Apr 19, 2026
from
Rome (Civitavecchia), Italy
Up to 3 deal
s
including an Avoya Exclusive
From
$7,999
63% Off List
List Price
$21,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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12-Night Mediterranean Cruise
$9,299
61% Off List
Regent Cruises – Seven Seas Grandeur
5.0
(3)
5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
View more
Date:
May 05, 2026
Ports:
Istanbul → Dikili → Kusadasi → Mykonos → Piraeus (Athens) → Gythion → Argostoli (Cephalonia) → Corfu → Kotor → Dubrovnik → Venice
Istanbul → Dikili → Kusadasi → Mykonos → Piraeus (Athens) → Gythion → Argostoli (Cephalonia) → Corfu → Kotor → Dubrovnik → Venice
Departs
May 05, 2026
from
Istanbul, Turkey
Up to 3 deal
s
including an Avoya Exclusive
From
$9,299
61% Off List
List Price
$23,998
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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7-Night Mediterranean Cruise
$5,799
64% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
May 08, 2026
Ports:
Rome (Civitavecchia) → Naples → Valletta → Katakolon → Santorini → Mykonos → Piraeus (Athens)
Departs
May 08, 2026
from
Rome (Civitavecchia), Italy
Up to 3 deal
s
including an Avoya Exclusive
From
$5,799
64% Off List
List Price
$15,998
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
7-Night Mediterranean Cruise
$5,799
64% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
May 15, 2026
Ports:
Piraeus (Athens) → Santorini → Heraklion → Mykonos → Izmir → Istanbul
Departs
May 15, 2026
from
Piraeus (Athens), Greece
Up to 3 deal
s
including an Avoya Exclusive
From
$5,799
64% Off List
List Price
$15,998
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
7-Night Mediterranean Cruise
$5,899
64% Off List
Regent Cruises – Seven Seas Grandeur
5.0
(3)
5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
View more
Date:
May 17, 2026
Ports:
Venice → Split → Dubrovnik → Kotor → Corfu → Sorrento → Rome (Civitavecchia)
Departs
May 17, 2026
from
Venice, Italy
Up to 3 deal
s
including an Avoya Exclusive
From
$5,899
64% Off List
List Price
$16,398
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
12-Night Mediterranean Cruise
$9,199
61% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
May 21, 2026
Ports:
Barcelona → Messina → Dubrovnik → Kotor → Corfu → Gythion → Rhodes → Santorini → Mykonos → Piraeus (Athens)
Departs
May 21, 2026
from
Barcelona, Spain
Up to 3 deal
s
including an Avoya Exclusive
From
$9,199
61% Off List
List Price
$23,798
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
Roundtrip
12-Night Mediterranean Cruise
$9,799
62% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
May 22, 2026
Ports:
Istanbul → Kavalla → Thessaloniki → Volos → Piraeus (Athens) → Mykonos → Heraklion → Marmaris → Izmir → Istanbul
Departs
May 22, 2026
from
Istanbul, Turkey
Up to 3 deal
s
including an Avoya Exclusive
From
$9,799
62% Off List
List Price
$25,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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14-Night Mediterranean Cruise
$10,699
62% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Jun 02, 2026
Ports:
Piraeus (Athens) → Volos → Thessaloniki → Istanbul → Mykonos → Santorini → Heraklion → Katakolon → Kotor → Split → Venice
Piraeus (Athens) → Volos → Thessaloniki → Istanbul → Mykonos → Santorini → Heraklion → Katakolon → Kotor → Split → Venice
Departs
Jun 02, 2026
from
Piraeus (Athens), Greece
Up to 3 deal
s
including an Avoya Exclusive
From
$10,699
62% Off List
List Price
$27,798
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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10-Night Mediterranean Cruise
$9,299
61% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
Jun 03, 2026
Ports:
Istanbul → Bozcaada → Kusadasi → Alexandria → Limassol → Rhodes → Santorini → Piraeus (Athens)
Departs
Jun 03, 2026
from
Istanbul, Turkey
Up to 3 deal
s
including an Avoya Exclusive
From
$9,299
61% Off List
List Price
$23,998
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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12-Night Mediterranean Cruise
$10,049
61% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Jun 16, 2026
Ports:
Venice → Dubrovnik → Heraklion → Piraeus (Athens) → Istanbul
Departs
Jun 16, 2026
from
Venice, Italy
Up to 3 deal
s
including an Avoya Exclusive
From
$10,049
61% Off List
List Price
$25,898
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
Share
10-Night Mediterranean Cruise
$8,999
62% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
Jun 19, 2026
Ports:
Piraeus (Athens) → Valletta → Trapani → La Goulette → Palma De Mallorca → Almeria → Cadiz → Portimao → Lisbon
Departs
Jun 19, 2026
from
Piraeus (Athens), Greece
Up to 3 deal
s
including an Avoya Exclusive
From
$8,999
62% Off List
List Price
$23,598
Get Availability
More Details
Top Picks Rank:
7
Save
Share
View Expanded Details
Save
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17-Night Mediterranean Cruise
$14,599
63% Off List
Regent Cruises – Seven Seas Splendor
4.2
(30)
5 Star
53%
4 Star
27%
3 Star
13%
2 Star
3%
1 Star
3%
View more
Date:
Jun 19, 2026
Ports:
Piraeus (Athens) → Valletta → Trapani → La Goulette → Palma De Mallorca → Almeria → Cadiz → Portimao → Lisbon → Tangier → Ibiza → Barcelona → Marseille → Monte Carlo
Piraeus (Athens) → Valletta → Trapani → La Goulette → Palma De Mallorca → Almeria → Cadiz → Portimao → Lisbon → Tangier → Ibiza → Barcelona → Marseille → Monte Carlo
Departs
Jun 19, 2026
from
Piraeus (Athens), Greece
Up to 3 deal
s
including an Avoya Exclusive
From
$14,599
63% Off List
List Price
$39,398
Get Availability
More Details
Top Picks Rank:
7
Save
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View Expanded Details
Save
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12-Night Mediterranean Cruise
$10,399
61% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Jun 28, 2026
Ports:
Istanbul → Lesbos → Kusadasi → Heraklion → Dubrovnik → Kotor → Corfu → Crotone → Valletta → Sorrento → Rome (Civitavecchia)
Istanbul → Lesbos → Kusadasi → Heraklion → Dubrovnik → Kotor → Corfu → Crotone → Valletta → Sorrento → Rome (Civitavecchia)
Departs
Jun 28, 2026
from
Istanbul, Turkey
Up to 3 deal
s
including an Avoya Exclusive
From
$10,399
61% Off List
List Price
$26,398
Get Availability
More Details
Top Picks Rank:
7
Save
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View Expanded Details
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22-Night Mediterranean Cruise
$18,099
59% Off List
Regent Cruises – Seven Seas Voyager
4.5
(82)
5 Star
74%
4 Star
16%
3 Star
2%
2 Star
5%
1 Star
2%
View more
Date:
Jun 28, 2026
Ports:
Istanbul → Lesbos → Kusadasi → Heraklion → Dubrovnik → Kotor → Corfu → Crotone → Valletta → Sorrento → Rome (Civitavecchia) → Livorno → Toulon → Barcelona → Palma De Mallorca → Malaga → Gibraltar → Portimao → Lisbon
Istanbul → Lesbos → Kusadasi → Heraklion → Dubrovnik → Kotor → Corfu → Crotone → Valletta → Sorrento → Rome (Civitavecchia) → Livorno → Toulon → Barcelona → Palma De Mallorca → Malaga → Gibraltar → Portimao → Lisbon
Departs
Jun 28, 2026
from
Istanbul, Turkey
Up to 3 deal
s
including an Avoya Exclusive
From
$18,099
59% Off List
List Price
$44,398
Get Availability
More Details
Top Picks Rank:
7
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