22-night south america cruise
Suite From
$15,099
60% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Nov 09, 2026 from Miami, Florida
Up to 3 deals including an Avoya ExclusiveView Expanded Details
Regent Cruises to South America
Showing 1-12 of 12 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Up to 3 deals including an Avoya Exclusive
18-night south america cruise
Suite From
$12,720
68% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Feb 02, 2027 from Buenos Aires, Argentina
Up to 3 deals including Avoya ExclusivesView Expanded Details
18-night south america cruise
Suite From
$16,149
59% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Feb 20, 2027 from Buenos Aires, Argentina
Up to 3 deals including Avoya ExclusivesView Expanded Details
18-night south america cruise
Suite From
$16,599
59% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Jan 04, 2027 from Miami, Florida
Up to 2 deals including an Avoya ExclusiveView Expanded Details
11-night south america cruise
Suite From
$13,199
58% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Jan 22, 2027 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya ExclusiveView Expanded Details
22-night south america cruise
Suite From
$23,449
56% Off List
Regent Cruises – Seven Seas Grandeur
5.03 Reviews
Departs Mar 09, 2027 from Panama City (Fuerte Amador), Panama
Up to 2 deals including an Avoya ExclusiveView Expanded Details
16-night south america cruise
Suite From
$13,399
59% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Mar 10, 2027 from Lima (Callao), Peru
Up to 2 deals including an Avoya ExclusiveView Expanded Details
30-night south america cruise
Suite From
$25,049
61% Off List
Regent Cruises – Seven Seas Voyager
4.582 Reviews
Departs Jan 27, 2028 from Lima (Callao), Peru
Up to 3 deals including an Avoya ExclusiveView Expanded Details
21-night south america cruise
Suite From
$21,799
59% Off List
Regent Cruises – Seven Seas Voyager
4.582 Reviews
Departs Feb 26, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya ExclusiveView Expanded Details
17-night south america cruise
Suite From
$14,299
60% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Feb 01, 2029 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
25-night south america cruise
Suite From
$20,149
61% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Feb 01, 2029 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
8-night south america cruise
Suite From
$6,899
63% Off List
Regent Cruises – Seven Seas Mariner
4.5103 Reviews
Departs Feb 18, 2029 from Santiago (Valparaiso), Chile
Up to 2 deals
View Expanded Details
AmaWaterways American Cruise Lines Atlas Ocean Voyages Aurora Expeditions Avalon Waterways Azamara Cruises Carnival Cruises Celebrity Cruises Celebrity River Cruises Celestyal Cruises Crystal Cruises Cunard Disney Cruises Explora Journeys Holland America HX Cruises Margaritaville at Sea MSC Cruises Norwegian Cruise Line Oceania Cruises Paul Gauguin Cruises Ponant Explorations Princess Cruises Regent Cruises Riviera Travel Royal Caribbean Scenic River Cruises Seabourn Silversea Swan Hellenic Tauck River Cruises Viking Ocean Cruises Viking River Cruises Virgin Voyages Windstar Cruises
Don't Miss the Latest Deals!
- Save favorite vacations & searches
- Early access to promotions
- Exclusive deals, discounts & prices
- Plus more!
Talk to a Vacation Planner
Call at 1-888-447-8459
1-888-447-8459
or click here to submit a form and we will connect you with a Personal Travel Advisor that specializes in the type of travel you are interested in. 
Why Choose Avoya?
From powerful online search, to specialized vacation planning services, and exclusive deals and extras - discover what makes Avoya Travel a different, better type of travel company.