No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. Plus, our Low Price Guarantee! No Avoya Fees on Cruises or Tours.
Click Here!
No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. Plus, our Low Price Guarantee! No Avoya Fees on Cruises or Tours.
Click Here!
Cruises from San Diego, California
Showing
1-25 of
182
results
Meet Natalie Thompson, one of Avoya's trusted travel
advisors.
Our team has helped more than 2.5 million travelers save
time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan
the vacation of your dreams. From finding the best price to
answering every question, we are with you every step of the way
at no extra cost.
7-night mexico cruise
$911
2% Off
Royal Caribbean –
Serenade of the Seas
Departs
Nov 22, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$714
2% Off
Royal Caribbean –
Serenade of the Seas
Departs
Oct 18, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$989
7% Off
Royal Caribbean –
Serenade of the Seas
Departs
Dec 20, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$1,091
4% Off
Royal Caribbean –
Serenade of the Seas
Departs
Dec 27, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$713
12% Off
Royal Caribbean –
Serenade of the Seas
Departs
Jan 28, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$829
Royal Caribbean –
Serenade of the Seas
Departs
Feb 28, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
Avoya Exclusive Rate
4-night mexico cruise
$544
Royal Caribbean –
Serenade of the Seas
Departs
Mar 07, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$834
8% Off
Royal Caribbean –
Serenade of the Seas
Departs
Mar 28, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
Avoya Exclusive Rate
7-night mexico cruise
$801
12% Off
Royal Caribbean –
Serenade of the Seas
Departs
Apr 25, 2027
from
San Diego, California
Up to 2 deals
including an Avoya Exclusive
Avoya Exclusive Rate
2-night mexico cruise
$318
Royal Caribbean –
Serenade of the Seas
Departs
Oct 02, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$770
Royal Caribbean –
Serenade of the Seas
Departs
Oct 04, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
4-night mexico cruise
$565
Royal Caribbean –
Serenade of the Seas
Departs
Oct 11, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
3-night mexico cruise
$489
Royal Caribbean –
Serenade of the Seas
Departs
Oct 15, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$679
Royal Caribbean –
Serenade of the Seas
Departs
Oct 25, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$693
Royal Caribbean –
Serenade of the Seas
Departs
Nov 01, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$662
Royal Caribbean –
Serenade of the Seas
Departs
Nov 08, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$690
Royal Caribbean –
Serenade of the Seas
Departs
Nov 15, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
4-night mexico cruise
$466
Royal Caribbean –
Serenade of the Seas
Departs
Nov 29, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
3-night mexico cruise
$409
Royal Caribbean –
Serenade of the Seas
Departs
Dec 03, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
4-night mexico cruise
$466
Royal Caribbean –
Serenade of the Seas
Departs
Dec 06, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
3-night mexico cruise
$409
Royal Caribbean –
Serenade of the Seas
Departs
Dec 10, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$693
Royal Caribbean –
Serenade of the Seas
Departs
Dec 13, 2026
from
San Diego, California
Up to 4 deals
including Avoya Exclusives
7-night mexico cruise
$784
Royal Caribbean –
Serenade of the Seas
Departs
Jan 03, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
4-night mexico cruise
$535
Royal Caribbean –
Serenade of the Seas
Departs
Jan 10, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
3-night mexico cruise
$486
Royal Caribbean –
Serenade of the Seas
Departs
Jan 14, 2027
from
San Diego, California
Up to 3 deals
including Avoya Exclusives
Cruises from San Diego, California
Cruises from San Diego are a wonderful option for guests departing from the West Coast. Offering varied itineraries for cruisers both regionally and out-of-state, visitors sailings from this North America Departure Port are also convenient – as before or after your San Diego cruise, you can explore the city’s unique attractions. Popular destinations that you can visit on cruises from San Diego include Mexico, Hawaii, and more!