Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best Mediterranean Cruises

Showing 401-425 of 7,098 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
7-night mediterranean cruise
$1,411
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Aug 17, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,152
Princess Cruises – Enchanted Princess
4.4 (79)
Departs Aug 18, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
7-night europe cruise
$1,270
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Aug 22, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
11-night mediterranean cruise
$3,539
Azamara Cruises – Azamara Onward
4.5 (15)
Departs Aug 22, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including Avoya Exclusives
Secret Rate
7-night europe cruise
$1,305
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Aug 24, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
9-night mediterranean cruise
$8,549
63% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Aug 24, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,134
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Aug 29, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,514
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Aug 30, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
Avoya Exclusive Rate
7-night mediterranean cruise
$1,154
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Aug 31, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,222
Princess Cruises – Enchanted Princess
4.4 (79)
Departs Sep 01, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,003
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Sep 05, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,079
Princess Cruises – Sun Princess
4.3 (7)
Departs Sep 05, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
7-night mediterranean cruise
$1,378
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Sep 06, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
Avoya Exclusive Rate
10-night mediterranean cruise
$8,499
62% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Sep 12, 2026 from Venice, Italy
Up to 3 deals including an Avoya Exclusive
11-night mediterranean cruise
$5,059
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Sep 13, 2026 from Barcelona, Spain
Up to 2 deals including Avoya Exclusives
Secret Rate
7-night mediterranean cruise
$1,309
Princess Cruises – Sun Princess
4.3 (7)
Departs Sep 26, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
7-night mediterranean cruise
$1,704
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Sep 28, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$3,960
55% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Oct 03, 2026 from Trieste, Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,564
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Oct 11, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
14-night mediterranean cruise
$8,050
72% Off List
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Oct 12, 2026 from Piraeus (Athens), Greece
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$7,599
50% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Oct 13, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,072
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Oct 17, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,209
Princess Cruises – Sun Princess
4.3 (7)
Departs Oct 17, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
14-night mediterranean cruise
$7,875
55% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Oct 17, 2026 from Istanbul, Turkey
Up to 5 deals including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$3,079
Princess Cruises – Sky Princess
4.3 (64)
Departs Oct 24, 2026 from Southampton, United Kingdom
Up to 5 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo