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Best Mediterranean Cruises

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5-night mediterranean cruise
$692
65% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Apr 16, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$869
51% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Apr 16, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals
7-night mediterranean cruise
$605
66% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 17, 2026 from Ancona, Italy
Up to 3 deals
7-night mediterranean cruise
$821
56% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Apr 17, 2026 from BRINDISI
Up to 3 deals
5-night mediterranean cruise
$961
52% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Apr 17, 2026 from Marseille, France
Up to 3 deals
5-night mediterranean cruise
$520
59% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Apr 18, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$629
66% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 18, 2026 from Venice, Italy
Up to 2 deals
7-night mediterranean cruise
$775
57% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Apr 18, 2026 from Bari, Italy
Up to 2 deals
5-night mediterranean cruise
$880
MSC Cruises – MSC Musica
3.5 (4)
Departs Apr 18, 2026 from Barcelona, Spain
7-night mediterranean cruise
$1,069
52% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 18, 2026 from Barcelona, Spain
Up to 1 deal
5-night mediterranean cruise
$499
MSC Cruises – MSC World Europa
2.0 (3)
Departs Apr 19, 2026 from Genoa, Italy
5-night mediterranean cruise
$537
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Apr 19, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$871
56% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Apr 19, 2026 from Venice, Italy
Up to 2 deals
7-night mediterranean cruise
$1,198
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 19, 2026 from Marseille, France
Up to 2 deals
7-night mediterranean cruise
$6,349
2% Off List
Viking Ocean Cruises – Viking Sea
4.4 (38)
Departs Apr 19, 2026 from Rome (Civitavecchia), Italy
2-night mediterranean cruise
$259
MSC Cruises – MSC Musica
3.5 (4)
Departs Apr 20, 2026 from Rome (Civitavecchia), Italy
3-night mediterranean cruise
$299
MSC Cruises – MSC Musica
3.5 (4)
Departs Apr 20, 2026 from Rome (Civitavecchia), Italy
5-night mediterranean cruise
$439
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 20, 2026 from Genoa, Italy
3-night mediterranean cruise
$509
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Apr 20, 2026 from Marseille, France
6-night mediterranean cruise
$879
MSC Cruises – MSC Musica
3.5 (4)
Departs Apr 20, 2026 from Rome (Civitavecchia), Italy
8-night mediterranean cruise
$929
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 20, 2026 from Genoa, Italy
7-night mediterranean cruise
$1,064
45% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Apr 20, 2026 from Rome (Civitavecchia), Italy
Up to 1 deal
7-night mediterranean cruise
$1,079
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 20, 2026 from Genoa, Italy
7-night mediterranean cruise
$6,199
Viking Ocean Cruises – Viking Mars
3.6 (10)
Departs Apr 20, 2026 from Venice, Italy
Up to 1 deal including an Avoya Exclusive
4-night mediterranean cruise
$605
MSC Cruises – MSC Splendida
4.7 (9)
Departs Apr 21, 2026 from Naples, Italy

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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