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Best Mediterranean Cruises

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7-night mediterranean cruise
$822
54% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Sep 26, 2026 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$891
54% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Sep 26, 2026 from Bari, Italy
Up to 2 deals
7-night mediterranean cruise
$1,023
52% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 26, 2026 from Split, Croatia
Up to 2 deals
7-night mediterranean cruise
$1,066
41% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Sep 26, 2026 from Valencia, Spain
Up to 3 deals
7-night mediterranean cruise
$1,120
46% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Sep 26, 2026 from Naples, Italy
Up to 3 deals
7-night mediterranean cruise
$1,158
46% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Sep 26, 2026 from Genoa, Italy
Up to 2 deals
7-night mediterranean cruise
$1,201
44% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Sep 26, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$1,266
49% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Sep 26, 2026 from Marseille, France
Up to 2 deals
7-night mediterranean cruise
$5,099
Viking Ocean Cruises – Viking Neptune
4.1 (9)
Departs Sep 26, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
14-night mediterranean cruise
$12,298
Viking Ocean Cruises – Viking Neptune
4.1 (9)
Departs Sep 26, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
7-night mediterranean cruise
$1,010
49% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Sep 27, 2026 from Livorno, Italy
Up to 3 deals
7-night mediterranean cruise
$1,070
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 27, 2026 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$1,136
48% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Sep 27, 2026 from Barcelona, Spain
Up to 2 deals
7-night mediterranean cruise
$1,237
42% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Sep 27, 2026 from Cannes, France
Up to 3 deals
9-night mediterranean cruise
$1,361
52% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Sep 27, 2026 from Piraeus (Athens), Greece
Up to 3 deals
10-night mediterranean cruise
$1,444
45% Off List
MSC Cruises – MSC Opera
4.0 (5)
Departs Sep 27, 2026 from Alicante, Spain
Up to 3 deals
7-night mediterranean cruise
$1,552
38% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Sep 27, 2026 from Genoa, Italy
Up to 2 deals
7-night mediterranean cruise
$1,559
32% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Sep 27, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals
7-night mediterranean cruise
$6,204
Seabourn – Seabourn Quest
4.6 (43)
Departs Sep 27, 2026 from Dubrovnik, Croatia
Up to 2 deals including Avoya Exclusives
Secret Rate
14-night mediterranean cruise
$14,534
Seabourn – Seabourn Quest
4.6 (43)
Departs Sep 27, 2026 from Dubrovnik, Croatia
Up to 2 deals including Avoya Exclusives
Secret Rate
21-night mediterranean cruise
$37,909
Seabourn – Seabourn Quest
4.6 (43)
Departs Sep 27, 2026 from Dubrovnik, Croatia
Up to 2 deals including Avoya Exclusives
Secret Rate
7-night mediterranean cruise
$1,089
50% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 28, 2026 from Kusadasi, Turkey
Up to 3 deals
7-night mediterranean cruise
$1,117
47% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Sep 28, 2026 from Genoa, Italy
Up to 1 deal
7-night mediterranean cruise
$1,120
46% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Sep 28, 2026 from Marseille, France
Up to 3 deals
7-night mediterranean cruise
$1,257
42% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Sep 28, 2026 from Marseille, France
Up to 2 deals

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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