Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best Mediterranean Cruises

Showing 3976-4000 of 7,103 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
7-night mediterranean cruise
$975
52% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Oct 18, 2026 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$1,106
47% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 18, 2026 from Barcelona, Spain
Up to 2 deals
7-night mediterranean cruise
$1,212
48% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 18, 2026 from Genoa, Italy
Up to 2 deals
7-night mediterranean cruise
$1,262
36% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 18, 2026 from Cannes, France
Up to 3 deals
7-night mediterranean cruise
$1,269
33% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 18, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals
7-night mediterranean cruise
$4,589
Seabourn – Seabourn Quest
4.6 (43)
Departs Oct 18, 2026 from Istanbul, Turkey
Up to 2 deals including Avoya Exclusives
Secret Rate
14-night mediterranean cruise
$9,264
Seabourn – Seabourn Quest
4.6 (43)
Departs Oct 18, 2026 from Istanbul, Turkey
Up to 2 deals including Avoya Exclusives
Secret Rate
23-night mediterranean cruise
$14,874
Seabourn – Seabourn Quest
4.6 (43)
Departs Oct 18, 2026 from Istanbul, Turkey
Up to 2 deals including Avoya Exclusives
Secret Rate
4-night mediterranean cruise
$798
34% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Oct 19, 2026 from Barcelona, Spain
Up to 2 deals
7-night mediterranean cruise
$918
57% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Oct 19, 2026 from Kusadasi, Turkey
Up to 3 deals
7-night mediterranean cruise
$1,060
43% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 19, 2026 from Palermo, Italy
Up to 2 deals
7-night mediterranean cruise
$1,152
41% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 19, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$1,200
42% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 19, 2026 from Marseille, France
Up to 2 deals
7-night mediterranean cruise
$1,463
38% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 19, 2026 from Naples, Italy
Up to 2 deals
4-night mediterranean cruise
$563
49% Off List
MSC Cruises – MSC Euribia
Departs Oct 20, 2026 from Barcelona, Spain
Up to 3 deals
6-night mediterranean cruise
$862
54% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Oct 20, 2026 from Piraeus (Athens), Greece
Up to 2 deals
7-night mediterranean cruise
$967
52% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 20, 2026 from Livorno, Italy
Up to 2 deals
7-night mediterranean cruise
$1,276
42% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 20, 2026 from Messina, Italy
Up to 2 deals
9-night mediterranean cruise
$1,403
48% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Oct 20, 2026 from Bari, Italy
Up to 3 deals
4-night mediterranean cruise
$465
48% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Oct 21, 2026 from Genoa, Italy
Up to 2 deals
4-night mediterranean cruise
$516
49% Off List
MSC Cruises – MSC Euribia
Departs Oct 21, 2026 from Marseille, France
Up to 3 deals
7-night mediterranean cruise
$1,070
45% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 21, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$1,284
48% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 21, 2026 from Cagliari, Sardinia, Italy
Up to 2 deals
7-night mediterranean cruise
$1,326
40% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 21, 2026 from Valletta, Malta
Up to 2 deals
9-night mediterranean cruise
$1,391
45% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Oct 21, 2026 from Trieste, Italy
Up to 3 deals

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada: 1-888-877-7042
UK: 0-800-098-8475
Australia: 1-800-651-320
International: 001-760-305-5070
Avoya Travel. Beyond The Web.®
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo