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Best Mediterranean Cruises

Showing 451-475 of 6,924 results
9-night mediterranean cruise
$3,699
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 15, 2028 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$10,549
60% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Dec 09, 2025 from Lisbon, Portugal
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$9,949
61% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Mar 23, 2026 from Lisbon, Portugal
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,341
Princess Cruises – Sun Princess
4.3 (7)
Departs Apr 11, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
8-night mediterranean cruise
$1,854
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Apr 16, 2026 from Barcelona, Spain
Up to 4 deals including Avoya Exclusives
14-night mediterranean cruise
$12,049
60% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (3)
Departs Apr 21, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
9-night mediterranean cruise
$2,423
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Apr 24, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,134
Princess Cruises – Enchanted Princess
4.4 (79)
Departs Apr 25, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,208
Princess Cruises – Sun Princess
4.3 (7)
Departs May 02, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$9,999
60% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (3)
Departs May 05, 2026 from Istanbul, Turkey
Up to 2 deals including an Avoya Exclusive
9-night mediterranean cruise
$2,022
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs May 07, 2026 from Barcelona, Spain
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,024
Princess Cruises – Enchanted Princess
4.4 (79)
Departs May 12, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$6,899
62% Off List
Regent Cruises – Seven Seas Splendor
4.3 (31)
Departs May 15, 2026 from Piraeus (Athens), Greece
Up to 2 deals including an Avoya Exclusive
5-night mediterranean cruise
$969
Azamara Cruises – Azamara Journey
4.6 (158)
Departs May 21, 2026 from Barcelona, Spain
Up to 2 deals including Avoya Exclusives
12-night mediterranean cruise
$11,349
59% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs May 21, 2026 from Barcelona, Spain
Up to 2 deals including an Avoya Exclusive
10-night mediterranean cruise
$2,295
Celebrity Cruises – Celebrity Xcel
Departs May 22, 2026 from Barcelona, Spain
Up to 5 deals including an Avoya Exclusive
12-night mediterranean cruise
$10,449
61% Off List
Regent Cruises – Seven Seas Splendor
4.3 (31)
Departs May 22, 2026 from Istanbul, Turkey
Up to 3 deals including an Avoya Exclusive
14-night mediterranean cruise
$4,889
Azamara Cruises – Azamara Onward
4.5 (15)
Departs May 28, 2026 from Gran Canaria, Canary Islands, Spain
Up to 2 deals including an Avoya Exclusive
Secret Rate
14-night mediterranean cruise
$5,449
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Jun 02, 2026 from Barcelona, Spain
Up to 2 deals including Avoya Exclusives
14-night mediterranean cruise
$12,199
60% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Jun 02, 2026 from Piraeus (Athens), Greece
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,526
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Jun 08, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$2,039
Azamara Cruises – Azamara Onward
4.5 (15)
Departs Jun 11, 2026 from Barcelona, Spain
Up to 2 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,172
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Jun 14, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
11-night mediterranean cruise
$4,889
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Jun 16, 2026 from Bordeaux, France
Up to 3 deals including Avoya Exclusives
12-night mediterranean cruise
$7,670
75% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Jun 16, 2026 from Venice, Italy
Up to 3 deals including an Avoya Exclusive

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

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