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Best Mediterranean Cruises

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10-night mediterranean cruise
$4,299
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 05, 2028 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$2,099
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Apr 10, 2028 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
9-night mediterranean cruise
$3,699
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Apr 15, 2028 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$16,599
57% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Mar 23, 2026 from Lisbon, Portugal
Up to 4 deals including an Avoya Exclusive
10-night mediterranean cruise
$6,650
Silversea – Silver Muse
4.1 (29)
Departs Mar 25, 2026 from Piraeus (Athens), Greece
Up to 1 deal including an Avoya Exclusive
12-night mediterranean cruise
$6,840
Silversea – Silver Shadow
4.5 (40)
Departs Mar 27, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
7-night mediterranean cruise
$4,455
Atlas Ocean Voyages – World Navigator
4.6 (92)
Departs Apr 02, 2026 from Santa Cruz de Tenerife, Spain
Up to 1 deal including an Avoya Exclusive
Secret Rate
6-night mediterranean cruise
$1,631
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs Apr 04, 2026 from Raiatea, Society Islands, French Polynesia
Up to 1 deal including an Avoya Exclusive
11-night mediterranean cruise
$6,350
Silversea – Silver Ray
5.0 (3)
Departs Apr 05, 2026 from Lisbon, Portugal
Up to 1 deal including an Avoya Exclusive
9-night mediterranean cruise
$3,439
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Apr 07, 2026 from Lisbon, Portugal
Up to 1 deal including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$19,360
Silversea – Silver Shadow
4.5 (40)
Departs Apr 08, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
10-night mediterranean cruise
$6,199
50% Off List
Oceania Cruises – Nautica
4.4 (180)
Departs Apr 11, 2026 from Lisbon, Portugal
Up to 4 deals including an Avoya Exclusive
11-night mediterranean cruise
$8,550
Silversea – Silver Muse
4.1 (29)
Departs Apr 11, 2026 from Piraeus (Athens), Greece
Up to 1 deal including an Avoya Exclusive
4-night mediterranean cruise
$1,227
Atlas Ocean Voyages – World Voyager
4.5 (87)
Departs Apr 14, 2026 from Raiatea, Society Islands, French Polynesia
Up to 1 deal including an Avoya Exclusive
8-night mediterranean cruise
$1,122
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Apr 16, 2026 from Barcelona, Spain
Up to 4 deals including Avoya Exclusives
11-night mediterranean cruise
$4,109
Azamara Cruises – Azamara Journey
4.6 (158)
Departs Apr 17, 2026 from Rome (Civitavecchia), Italy
Up to 1 deal including an Avoya Exclusive
Secret Rate
14-night mediterranean cruise
$6,444
Atlas Ocean Voyages – World Navigator
4.6 (92)
Departs Apr 17, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Secret Rate
9-night mediterranean cruise
$2,173
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Apr 24, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$2,189
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Apr 25, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
Secret Rate
10-night mediterranean cruise
$2,819
Azamara Cruises – Azamara Quest
4.6 (126)
Departs May 02, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$6,950
Silversea – Silver Shadow
4.5 (40)
Departs May 02, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
7-night mediterranean cruise
$2,053
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs May 03, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
12-night mediterranean cruise
$11,799
59% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (3)
Departs May 05, 2026 from Istanbul, Turkey
Up to 3 deals including an Avoya Exclusive
9-night europe cruise
$1,592
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs May 07, 2026 from Barcelona, Spain
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$3,550
Silversea – Silver Spirit
4.5 (53)
Departs May 08, 2026 from Rome (Civitavecchia), Italy
Up to 1 deal including an Avoya Exclusive

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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