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Best Mediterranean Cruises

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11-night mediterranean cruise
$7,150
Silversea – Silver Ray
5.0 (3)
Departs May 08, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
10-night mediterranean cruise
$5,999
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs May 09, 2026 from Lisbon, Portugal
Up to 3 deals including Avoya Exclusives
7-night mediterranean cruise
$1,791
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs May 10, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,322
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs May 11, 2026 from Barcelona, Spain
Up to 4 deals including Avoya Exclusives
11-night mediterranean cruise
$8,430
Atlas Ocean Voyages – World Voyager
4.5 (87)
Departs May 13, 2026 from Oporto, Portugal
Up to 2 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$7,249
61% Off List
Regent Cruises – Seven Seas Splendor
4.3 (31)
Departs May 15, 2026 from Piraeus (Athens), Greece
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,556
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs May 16, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
7-night europe cruise
$1,874
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs May 17, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,386
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs May 18, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
10-night mediterranean cruise
$7,050
Silversea – Silver Ray
5.0 (3)
Departs May 19, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
12-night mediterranean cruise
$8,995
71% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs May 21, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
11-night mediterranean cruise
$2,619
Azamara Cruises – Azamara Quest
4.6 (126)
Departs May 22, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
Secret Rate
9-night mediterranean cruise
$6,550
Silversea – Silver Muse
4.1 (29)
Departs May 22, 2026 from Fusina (Venice)
Up to 1 deal including an Avoya Exclusive
12-night mediterranean cruise
$12,599
59% Off List
Regent Cruises – Seven Seas Splendor
4.3 (31)
Departs May 22, 2026 from Istanbul, Turkey
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,442
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs May 23, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,719
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs May 24, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,819
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs May 25, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$2,499
Azamara Cruises – Azamara Journey
4.6 (158)
Departs May 26, 2026 from Barcelona, Spain
Up to 1 deal including an Avoya Exclusive
Secret Rate
12-night mediterranean cruise
$6,850
Silversea – Silver Shadow
4.5 (40)
Departs May 26, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
7-night mediterranean cruise
$11,280
Silversea – Silver Shadow
4.5 (40)
Departs May 26, 2026 from Nice, France
Up to 1 deal including an Avoya Exclusive
11-night mediterranean cruise
$7,950
Silversea – Silver Ray
5.0 (3)
Departs May 29, 2026 from Rome (Civitavecchia), Italy
Up to 1 deal including an Avoya Exclusive
7-night europe cruise
$1,406
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs May 30, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,406
Royal Caribbean – Liberty of the Seas
4.5 (375)
Departs May 31, 2026 from Southampton, United Kingdom
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,749
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs May 31, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
11-night mediterranean cruise
$8,330
Silversea – Silver Muse
4.1 (29)
Departs May 31, 2026 from Fusina (Venice)
Up to 1 deal including an Avoya Exclusive

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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