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Best Mediterranean Cruises

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11-night mediterranean cruise
$3,999
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Oct 03, 2026 from Piraeus (Athens), Greece
Up to 2 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,935
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 04, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$6,000
Silversea – Silver Nova
5.0 (5)
Departs Oct 05, 2026 from Lavrion (Athens), Greece
Up to 2 deals including Avoya Exclusives
14-night mediterranean cruise
$11,200
Silversea – Silver Muse
4.1 (29)
Departs Oct 07, 2026 from Fusina (Venice)
Up to 2 deals including Avoya Exclusives
7-night mediterranean cruise
$1,890
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 08, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$8,000
Silversea – Silver Spirit
4.5 (53)
Departs Oct 08, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including Avoya Exclusives
10-night mediterranean cruise
$8,900
Silversea – Silver Ray
5.0 (3)
Departs Oct 08, 2026 from Monte Carlo, Monaco
Up to 2 deals including Avoya Exclusives
7-night mediterranean cruise
$1,037
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Oct 10, 2026 from Ravenna, Italy
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,834
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 11, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$6,000
Silversea – Silver Nova
5.0 (5)
Departs Oct 12, 2026 from Piraeus (Athens), Greece
Up to 2 deals including Avoya Exclusives
14-night mediterranean cruise
$8,960
72% Off List
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Oct 12, 2026 from Piraeus (Athens), Greece
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$6,600
Silversea – Silver Muse
4.1 (29)
Departs Oct 14, 2026 from Valletta, Malta
Up to 2 deals including Avoya Exclusives
7-night mediterranean cruise
$1,890
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 15, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,935
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 18, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
10-night mediterranean cruise
$7,700
Silversea – Silver Spirit
4.5 (53)
Departs Oct 18, 2026 from Fusina
Up to 2 deals including Avoya Exclusives
11-night mediterranean cruise
$8,400
Silversea – Silver Ray
5.0 (3)
Departs Oct 18, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including Avoya Exclusives
7-night mediterranean cruise
$5,800
Silversea – Silver Nova
5.0 (5)
Departs Oct 19, 2026 from Piraeus (Athens), Greece
Up to 2 deals including Avoya Exclusives
3-night mediterranean cruise
$1,322
Royal Caribbean – Legend of the Seas
4.6 (23)
Departs Oct 22, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$3,149
Azamara Cruises – Azamara Quest
4.6 (126)
Departs Oct 24, 2026 from Piraeus (Athens), Greece
Up to 2 deals including an Avoya Exclusive
10-night mediterranean cruise
$6,412
71% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Oct 24, 2026 from Piraeus (Athens), Greece
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$6,100
Silversea – Silver Dawn
4.6 (10)
Departs Oct 25, 2026 from Lisbon, Portugal
Up to 2 deals including Avoya Exclusives
11-night mediterranean cruise
$8,400
Silversea – Silver Nova
5.0 (5)
Departs Oct 26, 2026 from Piraeus (Athens), Greece
Up to 2 deals including Avoya Exclusives
10-night mediterranean cruise
$6,800
Silversea – Silver Spirit
4.5 (53)
Departs Oct 28, 2026 from Piraeus (Athens), Greece
Up to 2 deals including Avoya Exclusives
10-night mediterranean cruise
$6,700
Silversea – Silver Ray
5.0 (3)
Departs Oct 29, 2026 from Barcelona, Spain
Up to 2 deals including Avoya Exclusives
7-night mediterranean cruise
$2,819
Azamara Cruises – Azamara Onward
4.5 (15)
Departs Oct 31, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including an Avoya Exclusive

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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