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Holland America to South America

A Holland America South America cruise brings together ancient civilizations, exquisite wildlife, natural wonders, and more for an amazing and memorable cruise vacation. From spotting rare species in the Amazon to shopping in the bustling streets of Rio de Janeiro, a Holland America cruise to South America has a variety of events and activities on land to satisfy the thirst for adventure, and with Holland America Cruises, guests will enjoy everything from 7-day jaunts to extensive 68-day voyages. Onboard Holland America Line South American cruises travelers will have comfortable accommodations, a variety of menu options, onboard entertainment, and a front row seat to the wonders of South America.

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Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

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Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Holland America Oosterdam itinerary map

16-night south america cruise

Inside From

$1,899

Holland America – Oosterdam

4.2212 Reviews

Date:

Nov 18, 2026

Ports:

Departs Nov 18, 2026 from Fort Lauderdale, Florida

Up to 3 deals including Avoya Exclusives

Inside From

$1,899

View Expanded Details

Holland America Volendam itinerary map

27-night south america cruise

Inside From

$3,599

Holland America – Volendam

4.373 Reviews

Date:

Nov 25, 2026

Ports:

Departs Nov 25, 2026 from Fort Lauderdale, Florida

Up to 3 deals including Avoya Exclusives

Inside From

$3,599

View Expanded Details

Holland America Oosterdam itinerary map

16-night south america cruise

Inside From

$2,299

Holland America – Oosterdam

4.2212 Reviews

Date:

Mar 24, 2027

Ports:

Departs Mar 24, 2027 from San Antonio, Chile

Up to 3 deals including Avoya Exclusives

Inside From

$2,299

View Expanded Details

Holland America Volendam itinerary map

30-night south america cruise

Inside From

$4,414

Holland America – Volendam

4.373 Reviews

Date:

Nov 22, 2026

Ports:

Departs Nov 22, 2026 from New York City, New York

Up to 2 deals including an Avoya Exclusive

Inside From

$4,414

View Expanded Details

Holland America Oosterdam itinerary map

22-night south america cruise

Inside From

$5,269

Holland America – Oosterdam

4.2212 Reviews

Date:

Dec 19, 2026

Ports:

Departs Dec 19, 2026 from Buenos Aires, Argentina

Up to 2 deals including an Avoya Exclusive

Inside From

$5,269

View Expanded Details

Holland America Zaandam itinerary map

41-night south america cruise

Inside From

$8,999

Holland America – Zaandam

4.5132 Reviews

Date:

Jan 03, 2027

Ports:

Departs Jan 03, 2027 from Fort Lauderdale, Florida

Up to 1 deal including an Avoya Exclusive

Avoya Exclusive Rate

Inside From

$8,999

View Expanded Details

Holland America Zaandam itinerary map

70-night south america cruise

Inside From

$13,599

Holland America – Zaandam

4.5132 Reviews

Date:

Jan 03, 2027

Ports:

Departs Jan 03, 2027 from Fort Lauderdale, Florida

Up to 1 deal

Inside From

$13,599

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

26-night south america cruise

Inside From

$3,309

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Oct 07, 2027

Ports:

Departs Oct 07, 2027 from Vancouver, BC, Canada

Up to 3 deals including an Avoya Exclusive

Inside From

$3,309

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

41-night south america cruise

Inside From

$4,724

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Oct 07, 2027

Ports:

Departs Oct 07, 2027 from Vancouver, BC, Canada

Up to 3 deals including an Avoya Exclusive

Inside From

$4,724

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

21-night south america cruise

Inside From

$2,784

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Oct 12, 2027

Ports:

Departs Oct 12, 2027 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$2,784

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

36-night south america cruise

Inside From

$4,249

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Oct 12, 2027

Ports:

Departs Oct 12, 2027 from San Diego, California

Up to 3 deals including an Avoya Exclusive

Inside From

$4,249

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

15-night south america cruise

Inside From

$2,124

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Nov 02, 2027 View Other Dates →

Ports:

Departs Nov 02, 2027 from San Antonio, Chile

Up to 3 deals including an Avoya Exclusive

Inside From

$2,124

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

15-night south america cruise

Inside From

$1,924

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Nov 17, 2027

Ports:

Departs Nov 17, 2027 from Buenos Aires, Argentina

Up to 3 deals including an Avoya Exclusive

Inside From

$1,924

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

15-night south america cruise

Inside From

$1,924

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Dec 02, 2027 View Other Dates →

Ports:

Departs Dec 02, 2027 from San Antonio, Chile

Up to 3 deals including an Avoya Exclusive

Inside From

$1,924

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

22-night south america cruise

Inside From

$5,119

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Dec 17, 2027

Ports:

Departs Dec 17, 2027 from Buenos Aires, Argentina

Up to 3 deals including an Avoya Exclusive

Inside From

$5,119

View Expanded Details

Holland America Zuiderdam itinerary map

28-night south america cruise

Inside From

$6,179

Holland America – Zuiderdam

4.3156 Reviews

Date:

Jan 06, 2028

Ports:

Departs Jan 06, 2028 from Fort Lauderdale, Florida

Up to 3 deals including an Avoya Exclusive

Inside From

$6,179

View Expanded Details

Holland America Zaandam itinerary map

29-night south america cruise

Inside From

$5,999

Holland America – Zaandam

4.5132 Reviews

Date:

Feb 13, 2027

Ports:

Departs Feb 13, 2027 from Buenos Aires, Argentina

Up to 1 deal

Inside From

$5,999

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

22-night south america cruise

Inside From

$5,469

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Jan 08, 2028

Ports:

Departs Jan 08, 2028 from San Antonio, Chile

Up to 2 deals

Inside From

$5,469

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

22-night south america cruise

Inside From

$5,269

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Jan 30, 2028

Ports:

Departs Jan 30, 2028 from Buenos Aires, Argentina

Up to 2 deals

Inside From

$5,269

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

14-night south america cruise

Inside From

$2,439

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Feb 21, 2028

Ports:

Departs Feb 21, 2028 from San Antonio, Chile

Up to 2 deals

Inside From

$2,439

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

15-night south america cruise

Inside From

$2,674

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Mar 06, 2028

Ports:

Departs Mar 06, 2028 from Buenos Aires, Argentina

Up to 2 deals

Inside From

$2,674

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

32-night south america cruise

Inside From

$5,314

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Mar 06, 2028

Ports:

Departs Mar 06, 2028 from Buenos Aires, Argentina

Up to 2 deals

Inside From

$5,314

View Expanded Details

Holland America Nieuw Amsterdam itinerary map

17-night south america cruise

Inside From

$2,894

Holland America – Nieuw Amsterdam

4.3198 Reviews

Date:

Mar 21, 2028

Ports:

Departs Mar 21, 2028 from San Antonio, Chile

Up to 2 deals

Inside From

$2,894

View Expanded Details

Holland America Oosterdam itinerary map

31-night south america cruise

Balcony From

Call Us

Holland America – Oosterdam

4.2212 Reviews

Date:

Mar 09, 2027

Ports:

Departs Mar 09, 2027 from Buenos Aires, Argentina

Up to 2 deals including an Avoya Exclusive

Balcony From

Call Us

View Expanded Details

Holland America Oosterdam itinerary map

22-night south america cruise

Inside From

$4,674

Holland America – Oosterdam

4.2212 Reviews

Date:

Feb 01, 2027

Ports:

Departs Feb 01, 2027 from Buenos Aires, Argentina

Up to 3 deals including Avoya Exclusives

Avoya Exclusive Rate

Inside From

$4,674

View Expanded Details

Showing 1-25 of 30 results

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