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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$1,017

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Aug 12, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Puerto Plata → Nassau → Port Canaveral

Departs Aug 12, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,017

48% Off List

List Price

$1,956

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$725

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 13, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 13, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$725

49% Off List

List Price

$1,435

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$811

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 14, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Aug 14, 2028 from Miami, Florida

Up to 2 deals

Inside From

$811

47% Off List

List Price

$1,536

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$605

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 20, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 20, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$605

49% Off List

List Price

$1,195

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$635

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Aug 27, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Aug 27, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$635

49% Off List

List Price

$1,255

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$801

47% Off List

MSC Cruises – MSC World Atlantic

Date:

Sep 02, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Costa Maya → Cozumel → Nassau → Port Canaveral

Departs Sep 02, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$801

47% Off List

List Price

$1,524

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$585

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 03, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 03, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$585

49% Off List

List Price

$1,155

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$615

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 10, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 10, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$615

49% Off List

List Price

$1,215

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$313

44% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Sep 14, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Sep 14, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$313

44% Off List

List Price

$556

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,181

48% Off List

MSC Cruises – MSC World America

Date:

Sep 16, 2028 View Other Dates →

Ports:

Departs Sep 16, 2028 from Miami, Florida

Up to 2 deals

Inside From

$2,181

48% Off List

List Price

$4,186

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$585

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 17, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 17, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$585

49% Off List

List Price

$1,155

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$585

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Sep 24, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Sep 24, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$585

49% Off List

List Price

$1,155

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$767

47% Off List

MSC Cruises – MSC World Atlantic

Date:

Sep 30, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Costa Maya → Cozumel → Nassau → Port Canaveral

Departs Sep 30, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$767

47% Off List

List Price

$1,456

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,612

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Sep 30, 2028 View Other Dates →

Ports:

Departs Sep 30, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,612

48% Off List

List Price

$3,080

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$605

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 01, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 01, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$605

49% Off List

List Price

$1,195

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$635

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 08, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 08, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$635

49% Off List

List Price

$1,255

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$794

46% Off List

MSC Cruises – MSC World America

Date:

Oct 14, 2028 View Other Dates →

Ports:

Miami → Puerto Plata → San Juan → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 14, 2028 from Miami, Florida

Up to 2 deals

Inside From

$794

46% Off List

List Price

$1,467

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$565

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 15, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 15, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$565

49% Off List

List Price

$1,115

View Expanded Details

MSC Cruises MSC World America itinerary map

7-night caribbean cruise

Inside From

$848

47% Off List

MSC Cruises – MSC World America

Date:

Oct 21, 2028 View Other Dates →

Ports:

Miami → Roatan → Costa Maya → Cozumel → Ocean Cay MSC Marine Reserve Bahamas → Miami

Departs Oct 21, 2028 from Miami, Florida

Up to 2 deals

Inside From

$848

47% Off List

List Price

$1,610

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$1,681

47% Off List

MSC Cruises – MSC World America

Date:

Oct 21, 2028 View Other Dates →

Ports:

Departs Oct 21, 2028 from Miami, Florida

Up to 2 deals

Inside From

$1,681

47% Off List

List Price

$3,186

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$565

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 22, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 22, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$565

49% Off List

List Price

$1,115

View Expanded Details

MSC Cruises MSC Seascape itinerary map

7-night caribbean cruise

Inside From

$645

49% Off List

MSC Cruises – MSC Seascape

4.120 Reviews

Date:

Oct 29, 2028 View Other Dates →

Ports:

Galveston → Costa Maya → Roatan → Cozumel → Galveston

Departs Oct 29, 2028 from Galveston, Texas

Up to 2 deals

Inside From

$645

49% Off List

List Price

$1,275

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$857

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Nov 04, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Puerto Plata → Nassau → Port Canaveral

Departs Nov 04, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$857

48% Off List

List Price

$1,636

View Expanded Details

MSC Cruises MSC Poesia itinerary map

21-night caribbean cruise

Balcony From

Call Us

MSC Cruises – MSC Poesia

3.929 Reviews

Date:

Nov 12, 2026

Ports:

Departs Nov 12, 2026 from Miami, Florida

Up to 1 deal

Balcony From

Call Us

View Expanded Details

MSC Cruises MSC Opera itinerary map

4-night caribbean cruise

Balcony From

Call Us

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Apr 10, 2028 View Other Dates →

Ports:

La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Apr 10, 2028 from La Romana, Dominican Republic

Balcony From

Call Us

View Expanded Details

Showing 1151-1175 of 1,179 results

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