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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$929

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 07, 2028 View Other Dates →

Ports:

Departs Aug 07, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$929

49% Off List

List Price

$1,829

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,810

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 07, 2028 View Other Dates →

Ports:

Departs Aug 07, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,810

49% Off List

List Price

$3,550

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$369

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 11, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 11, 2028 from Miami, Florida

Up to 2 deals

Inside From

$369

44% Off List

List Price

$663

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$430

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 13, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 13, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$430

46% Off List

List Price

$800

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$646

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 14, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 14, 2028 from Miami, Florida

Up to 2 deals

Inside From

$646

46% Off List

List Price

$1,207

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$869

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 14, 2028 View Other Dates →

Ports:

Departs Aug 14, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$869

49% Off List

List Price

$1,709

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,728

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 14, 2028 View Other Dates →

Ports:

Departs Aug 14, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,728

49% Off List

List Price

$3,386

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$413

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 17, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 17, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$413

45% Off List

List Price

$756

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,669

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 17, 2028 View Other Dates →

Ports:

Departs Aug 17, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,669

49% Off List

List Price

$3,268

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$369

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 18, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 18, 2028 from Miami, Florida

Up to 2 deals

Inside From

$369

44% Off List

List Price

$663

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$818

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 18, 2028 View Other Dates →

Ports:

Departs Aug 18, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$818

49% Off List

List Price

$1,607

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$450

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 20, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 20, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$450

46% Off List

List Price

$840

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$386

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 21, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 21, 2028 from Miami, Florida

Up to 2 deals

Inside From

$386

44% Off List

List Price

$687

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,660

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 21, 2028 View Other Dates →

Ports:

Departs Aug 21, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,660

49% Off List

List Price

$3,250

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$343

44% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 24, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 24, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$343

44% Off List

List Price

$616

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$319

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 25, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 25, 2028 from Miami, Florida

Up to 2 deals

Inside From

$319

43% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$699

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 25, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Aug 25, 2028 from Fort de France, Martinique

Up to 1 deal

Inside From

$699

49% Off List

List Price

$1,369

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$390

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 27, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 27, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$390

46% Off List

List Price

$720

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$326

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Aug 28, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Aug 28, 2028 from Miami, Florida

Up to 2 deals

Inside From

$326

43% Off List

List Price

$567

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$739

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 28, 2028 View Other Dates →

Ports:

Departs Aug 28, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$739

49% Off List

List Price

$1,449

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,430

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 28, 2028 View Other Dates →

Ports:

Departs Aug 28, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,430

49% Off List

List Price

$2,790

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$343

44% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Aug 31, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Aug 31, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$343

44% Off List

List Price

$616

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,379

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Aug 31, 2028 View Other Dates →

Ports:

Departs Aug 31, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,379

49% Off List

List Price

$2,688

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$319

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Sep 01, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Sep 01, 2028 from Miami, Florida

Up to 2 deals

Inside From

$319

43% Off List

List Price

$563

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$679

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Sep 01, 2028 View Other Dates →

Ports:

Departs Sep 01, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$679

49% Off List

List Price

$1,329

View Expanded Details

Showing 876-900 of 1,181 results

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