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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$459

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 23, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 23, 2028 from Miami, Florida

Up to 2 deals

Inside From

$459

46% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$979

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 23, 2028 View Other Dates →

Ports:

Departs Jun 23, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$979

49% Off List

List Price

$1,929

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,401

48% Off List

MSC Cruises – MSC World America

Date:

Jun 24, 2028 View Other Dates →

Ports:

Departs Jun 24, 2028 from Miami, Florida

Up to 2 deals

Inside From

$2,401

48% Off List

List Price

$4,626

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$570

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 25, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jun 25, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$570

47% Off List

List Price

$1,080

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$456

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 26, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 26, 2028 from Miami, Florida

Up to 2 deals

Inside From

$456

45% Off List

List Price

$827

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,698

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 26, 2028 View Other Dates →

Ports:

Departs Jun 26, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,698

49% Off List

List Price

$3,326

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$533

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 29, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jun 29, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$533

46% Off List

List Price

$996

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$469

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 30, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 30, 2028 from Miami, Florida

Up to 2 deals

Inside From

$469

46% Off List

List Price

$863

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$919

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 30, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jun 30, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$919

49% Off List

List Price

$1,809

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$570

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 02, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jul 02, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$570

47% Off List

List Price

$1,080

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$476

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 03, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jul 03, 2028 from Miami, Florida

Up to 2 deals

Inside From

$476

45% Off List

List Price

$867

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$869

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 03, 2028 View Other Dates →

Ports:

Departs Jul 03, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$869

49% Off List

List Price

$1,709

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,820

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 03, 2028 View Other Dates →

Ports:

Departs Jul 03, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,820

49% Off List

List Price

$3,570

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$523

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 06, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jul 06, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$523

46% Off List

List Price

$976

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,899

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 06, 2028 View Other Dates →

Ports:

Departs Jul 06, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,899

49% Off List

List Price

$3,728

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$459

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 07, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jul 07, 2028 from Miami, Florida

Up to 2 deals

Inside From

$459

46% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$1,009

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 07, 2028 View Other Dates →

Ports:

Departs Jul 07, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$1,009

49% Off List

List Price

$1,989

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,451

48% Off List

MSC Cruises – MSC World America

Date:

Jul 08, 2028 View Other Dates →

Ports:

Departs Jul 08, 2028 from Miami, Florida

Up to 2 deals

Inside From

$2,451

48% Off List

List Price

$4,726

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$550

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 09, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jul 09, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$550

47% Off List

List Price

$1,040

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$476

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 10, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jul 10, 2028 from Miami, Florida

Up to 2 deals

Inside From

$476

45% Off List

List Price

$867

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$939

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 10, 2028 View Other Dates →

Ports:

Departs Jul 10, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$939

49% Off List

List Price

$1,849

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,768

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 10, 2028 View Other Dates →

Ports:

Departs Jul 10, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,768

49% Off List

List Price

$3,466

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$523

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jul 13, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jul 13, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$523

46% Off List

List Price

$976

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$469

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jul 14, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jul 14, 2028 from Miami, Florida

Up to 2 deals

Inside From

$469

46% Off List

List Price

$863

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$948

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jul 14, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jul 14, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$948

49% Off List

List Price

$1,867

View Expanded Details

Showing 826-850 of 1,181 results

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