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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$879

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 02, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jun 02, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$879

49% Off List

List Price

$1,729

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

7-night caribbean cruise

Inside From

$1,211

48% Off List

MSC Cruises – MSC World Atlantic

Date:

Jun 03, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Grand Turk → Puerto Plata → Nassau → Port Canaveral

Departs Jun 03, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,211

48% Off List

List Price

$2,344

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$386

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 05, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 05, 2028 from Miami, Florida

Up to 2 deals

Inside From

$386

44% Off List

List Price

$687

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$819

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 05, 2028 View Other Dates →

Ports:

Departs Jun 05, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$819

49% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$821

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 05, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Jun 05, 2028 from Miami, Florida

Up to 2 deals

Inside From

$821

47% Off List

List Price

$1,556

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,700

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 05, 2028 View Other Dates →

Ports:

Departs Jun 05, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,700

49% Off List

List Price

$3,330

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,818

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 08, 2028 View Other Dates →

Ports:

Departs Jun 08, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,818

49% Off List

List Price

$3,566

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$419

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 09, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 09, 2028 from Miami, Florida

Up to 2 deals

Inside From

$419

45% Off List

List Price

$763

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$959

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 09, 2028 View Other Dates →

Ports:

Departs Jun 09, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$959

49% Off List

List Price

$1,889

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,301

48% Off List

MSC Cruises – MSC World America

Date:

Jun 10, 2028 View Other Dates →

Ports:

Departs Jun 10, 2028 from Miami, Florida

Up to 2 deals

Inside From

$2,301

48% Off List

List Price

$4,426

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$500

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 11, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jun 11, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$500

47% Off List

List Price

$940

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$436

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 12, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 12, 2028 from Miami, Florida

Up to 2 deals

Inside From

$436

45% Off List

List Price

$787

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$838

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 12, 2028 View Other Dates →

Ports:

Departs Jun 12, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$838

49% Off List

List Price

$1,647

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$891

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 12, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Jun 12, 2028 from Miami, Florida

Up to 2 deals

Inside From

$891

47% Off List

List Price

$1,696

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,638

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 12, 2028 View Other Dates →

Ports:

Departs Jun 12, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,638

49% Off List

List Price

$3,206

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$459

46% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 16, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 16, 2028 from Miami, Florida

Up to 2 deals

Inside From

$459

46% Off List

List Price

$843

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$879

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 16, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs Jun 16, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$879

49% Off List

List Price

$1,729

View Expanded Details

MSC Cruises MSC World America itinerary map

14-night caribbean cruise

Inside From

$2,351

48% Off List

MSC Cruises – MSC World America

Date:

Jun 17, 2028 View Other Dates →

Ports:

Departs Jun 17, 2028 from Miami, Florida

Up to 2 deals

Inside From

$2,351

48% Off List

List Price

$4,526

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$570

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 18, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jun 18, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$570

47% Off List

List Price

$1,080

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$476

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 19, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 19, 2028 from Miami, Florida

Up to 2 deals

Inside From

$476

45% Off List

List Price

$867

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$819

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 19, 2028 View Other Dates →

Ports:

Departs Jun 19, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$819

49% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$928

48% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 19, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs Jun 19, 2028 from Miami, Florida

Up to 2 deals

Inside From

$928

48% Off List

List Price

$1,770

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,710

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 19, 2028 View Other Dates →

Ports:

Departs Jun 19, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,710

49% Off List

List Price

$3,350

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$533

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

Jun 22, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs Jun 22, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$533

46% Off List

List Price

$996

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,838

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

Jun 22, 2028 View Other Dates →

Ports:

Departs Jun 22, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,838

49% Off List

List Price

$3,606

View Expanded Details

Showing 801-825 of 1,181 results

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