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MSC Cruises to Caribbean

Onboard an MSC Cruises Caribbean vacation, guests will enjoy all that the Caribbean has to offer with a cruise line that is focused on providing family fun with a distinctly Italian elegance. MSC Cruise Line features the MSC Poesia in the Caribbean, with cruise vacation itineraries that include over 23 destinations and countless unforgettable shore excursions. On all MSC Cruises to the Caribbean, kids sail free, ensuring that each of MSC Cruises’ Caribbean cruises are a great value and a perfect choice for family getaways.

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Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

Meet Natalie Thompson, one of Avoya's trusted travel advisors.

Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.

Choose your adventure and let us handle the rest.

Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$829

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 12, 2028 View Other Dates →

Ports:

Departs May 12, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$829

49% Off List

List Price

$1,629

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$450

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 14, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs May 14, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$450

46% Off List

List Price

$840

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$366

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 15, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs May 15, 2028 from Miami, Florida

Up to 2 deals

Inside From

$366

43% Off List

List Price

$647

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$711

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 15, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs May 15, 2028 from Miami, Florida

Up to 2 deals

Inside From

$711

47% Off List

List Price

$1,336

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$819

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 15, 2028 View Other Dates →

Ports:

Departs May 15, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$819

49% Off List

List Price

$1,609

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,550

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 15, 2028 View Other Dates →

Ports:

Departs May 15, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,550

49% Off List

List Price

$3,030

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

3-night caribbean cruise

Inside From

$413

45% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 18, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs May 18, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$413

45% Off List

List Price

$756

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$359

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 19, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs May 19, 2028 from Miami, Florida

Up to 2 deals

Inside From

$359

44% Off List

List Price

$643

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$779

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 19, 2028 View Other Dates →

Ports:

Fort de France → Saint Johns → La Romana → Catalina Island Dominican Republic → Bridgetown → Fort de France

Departs May 19, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$779

49% Off List

List Price

$1,529

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$1,952

48% Off List

MSC Cruises – MSC World Atlantic

Date:

May 20, 2028 View Other Dates →

Ports:

Departs May 20, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$1,952

48% Off List

List Price

$3,760

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$450

46% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 21, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs May 21, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$450

46% Off List

List Price

$840

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$346

43% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 22, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs May 22, 2028 from Miami, Florida

Up to 2 deals

Inside From

$346

43% Off List

List Price

$607

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$749

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 22, 2028 View Other Dates →

Ports:

Departs May 22, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$749

49% Off List

List Price

$1,469

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$751

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 22, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs May 22, 2028 from Miami, Florida

Up to 2 deals

Inside From

$751

47% Off List

List Price

$1,416

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,448

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 22, 2028 View Other Dates →

Ports:

Departs May 22, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,448

49% Off List

List Price

$2,826

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,558

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 25, 2028 View Other Dates →

Ports:

Departs May 25, 2028 from Bridgetown, Barbados

Up to 1 deal

Inside From

$1,558

49% Off List

List Price

$3,046

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$399

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 26, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs May 26, 2028 from Miami, Florida

Up to 2 deals

Inside From

$399

45% Off List

List Price

$723

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$829

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 26, 2028 View Other Dates →

Ports:

Departs May 26, 2028 from Fort de France, Martinique

Up to 2 deals

Inside From

$829

49% Off List

List Price

$1,629

View Expanded Details

MSC Cruises MSC World Atlantic itinerary map

14-night caribbean cruise

Inside From

$2,200

48% Off List

MSC Cruises – MSC World Atlantic

Date:

May 27, 2028 View Other Dates →

Ports:

Departs May 27, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$2,200

48% Off List

List Price

$4,256

View Expanded Details

MSC Cruises MSC Grandiosa itinerary map

4-night caribbean cruise

Inside From

$460

47% Off List

MSC Cruises – MSC Grandiosa

5.02 Reviews

Date:

May 28, 2028 View Other Dates →

Ports:

Port Canaveral → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Port Canaveral

Departs May 28, 2028 from Port Canaveral, Florida

Up to 2 deals

Inside From

$460

47% Off List

List Price

$860

View Expanded Details

MSC Cruises MSC Seaside itinerary map

4-night caribbean cruise

Inside From

$406

44% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 29, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs May 29, 2028 from Miami, Florida

Up to 2 deals

Inside From

$406

44% Off List

List Price

$727

View Expanded Details

MSC Cruises MSC Opera itinerary map

7-night caribbean cruise

Inside From

$749

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 29, 2028 View Other Dates →

Ports:

Departs May 29, 2028 from La Romana, Dominican Republic

Up to 2 deals

Inside From

$749

49% Off List

List Price

$1,469

View Expanded Details

MSC Cruises MSC Seaside itinerary map

7-night caribbean cruise

Inside From

$761

47% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

May 29, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami → Nassau → Miami

Departs May 29, 2028 from Miami, Florida

Up to 2 deals

Inside From

$761

47% Off List

List Price

$1,436

View Expanded Details

MSC Cruises MSC Opera itinerary map

14-night caribbean cruise

Inside From

$1,518

49% Off List

MSC Cruises – MSC Opera

4.05 Reviews

Date:

May 29, 2028 View Other Dates →

Ports:

Departs May 29, 2028 from La Romana, Dominican Republic

Up to 1 deal

Inside From

$1,518

49% Off List

List Price

$2,966

View Expanded Details

MSC Cruises MSC Seaside itinerary map

3-night caribbean cruise

Inside From

$399

45% Off List

MSC Cruises – MSC Seaside

3.575 Reviews

Date:

Jun 02, 2028 View Other Dates →

Ports:

Miami → Ocean Cay MSC Marine Reserve Bahamas → Nassau → Miami

Departs Jun 02, 2028 from Miami, Florida

Up to 2 deals

Inside From

$399

45% Off List

List Price

$723

View Expanded Details

Showing 776-800 of 1,181 results

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