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Best South America Cruises

Showing 276-300 of 826 results
36-night south america cruise
Oceanview From
$13,186
Windstar Cruises – Wind Star
4.689 Reviews
Departs Jan 31, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$976
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 02, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
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7-night south america cruise
Balcony From
$1,516
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 02, 2027 from Salvador, Brazil
Up to 3 deals
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7-night south america cruise
Oceanview From
$3,613
Windstar Cruises – Star Legend
4.586 Reviews
Departs Feb 02, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$1,056
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 06, 2027 from Paranagua, Brazil
Up to 3 deals
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7-night south america cruise
Inside From
$1,239
43% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 06, 2027 from Santos, Brazil
Up to 3 deals
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7-night south america cruise
Inside From
$1,056
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 07, 2027 from Itajai
Up to 3 deals
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7-night south america cruise
Inside From
$1,066
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 09, 2027 from Salvador, Brazil
Up to 3 deals
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7-night south america cruise
Inside From
$1,136
48% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 09, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
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7-night south america cruise
Oceanview From
$2,582
Windstar Cruises – Star Legend
4.586 Reviews
Departs Feb 09, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
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13-night south america cruise
Oceanview From
$6,148
Windstar Cruises – Star Legend
4.586 Reviews
Departs Feb 09, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$896
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 13, 2027 from Paranagua, Brazil
Up to 3 deals
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7-night south america cruise
Inside From
$876
48% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 14, 2027 from Itajai
Up to 3 deals
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7-night south america cruise
Inside From
$1,379
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 14, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Inside From
$909
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 16, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
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6-night south america cruise
Oceanview From
$3,816
Windstar Cruises – Star Legend
4.586 Reviews
Departs Feb 16, 2027 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
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14-night south america cruise
Oceanview From
$7,806
Windstar Cruises – Star Legend
4.586 Reviews
Departs Feb 16, 2027 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$1,417
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 18, 2027 from Buenos Aires, Argentina
Up to 2 deals
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8-night south america cruise
Inside From
$1,985
34% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 19, 2027 from Buenos Aires, Argentina
Up to 3 deals
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7-night south america cruise
Inside From
$809
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 20, 2027 from Paranagua, Brazil
Up to 3 deals
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11-night south america cruise + tour
Suite From
$16,798
Seabourn – Seabourn Venture
5.02 Reviews
Departs Feb 20, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
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7-night south america cruise
Inside From
$779
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 21, 2027 from Itajai
Up to 3 deals
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11-night south america cruise + tour
Suite From
$12,673
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Feb 21, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
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7-night south america cruise
Oceanview From
$946
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 23, 2027 from Rio de Janeiro, Brazil
Up to 2 deals
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7-night south america cruise
Inside From
$786
MSC Cruises – MSC Musica
3.54 Reviews
Departs Feb 27, 2027 from Paranagua, Brazil
Up to 2 deals
View Expanded Details
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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