feature image

Best South America Cruises

Showing 326-350 of 827 results
4-night south america cruise
Inside From
$546
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Mar 22, 2027 from Santos, Brazil
Up to 3 deals
View Expanded Details
15-night south america cruise + tour
Suite From
$11,697
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 22, 2027 from Buenos Aires, Argentina
Secret Rate
View Expanded Details
36-night south america cruise + tour
Suite From
$17,083
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 22, 2027 from Buenos Aires, Argentina
Secret Rate
View Expanded Details
46-night south america cruise + tour
Suite From
$27,097
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 22, 2027 from Buenos Aires, Argentina
Secret Rate
View Expanded Details
15-night south america cruise + tour
Suite From
$15,897
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Mar 23, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
3-night south america cruise
Inside From
$468
48% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Mar 29, 2027 from Santos, Brazil
Up to 3 deals
View Expanded Details
49-night south america cruise + tour
Suite From
$38,197
Seabourn – Seabourn Venture
5.02 Reviews
Departs Oct 01, 2027 from Halifax, Nova Scotia, Canada
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
16-night south america cruise
Suite From
$10,598
Seabourn – Seabourn Venture
5.02 Reviews
Departs Oct 09, 2027 from Bridgetown, Barbados
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
41-night south america cruise + tour
Suite From
$33,897
Seabourn – Seabourn Venture
5.02 Reviews
Departs Oct 09, 2027 from Bridgetown, Barbados
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
18-night south america cruise + tour
Suite From
$21,497
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Oct 18, 2027 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
25-night south america cruise + tour
Suite From
$27,697
Seabourn – Seabourn Venture
5.02 Reviews
Departs Oct 25, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
11-night south america cruise + tour
Suite From
$14,897
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Nov 04, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
11-night south america cruise + tour
Suite From
$15,597
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Nov 14, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
21-night south america cruise + tour
Suite From
$26,497
Seabourn – Seabourn Venture
5.02 Reviews
Departs Nov 18, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
13-night south america cruise + tour
Suite From
$16,297
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Nov 24, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
7-night south america cruise
Inside From
$2,416
Windstar Cruises – Star Pride
4.595 Reviews
Departs Nov 29, 2027 from San Juan, Puerto Rico
Up to 2 deals including an Avoya Exclusive
View Expanded Details
14-night south america cruise
Inside From
$5,364
Windstar Cruises – Star Pride
4.595 Reviews
Departs Nov 29, 2027 from San Juan, Puerto Rico
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Inside From
$3,753
Windstar Cruises – Star Pride
4.595 Reviews
Departs Dec 06, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
View Expanded Details
11-night south america cruise + tour
Suite From
$18,297
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Dec 06, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
11-night south america cruise + tour
Suite From
$17,697
Seabourn – Seabourn Venture
5.02 Reviews
Departs Dec 08, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
7-night south america cruise
Inside From
$2,983
Windstar Cruises – Star Pride
4.595 Reviews
Departs Dec 13, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
View Expanded Details
21-night south america cruise + tour
Suite From
$34,997
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Dec 16, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
11-night south america cruise + tour
Suite From
$21,997
Seabourn – Seabourn Venture
5.02 Reviews
Departs Dec 18, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
7-night south america cruise
Inside From
$2,913
Windstar Cruises – Star Pride
4.595 Reviews
Departs Dec 20, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Oceanview From
$3,053
Windstar Cruises – Star Pride
4.595 Reviews
Departs Dec 27, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
View Expanded Details
  1. 1…
  2. 12
  3. 13
  4. 14
  5. 15
  6. 16
  7. …34
South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?