feature image

Best South America Cruises

Showing 426-450 of 827 results
9-night south america cruise
Balcony From
$1,870
56% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Jan 26, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
View Expanded Details
7-night south america cruise
Inside From
$1,397
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Jan 28, 2027 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
3-night south america cruise
Inside From
$659
MSC Cruises – MSC Divina
3.892 Reviews
Departs Jan 29, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
4-night south america cruise
Inside From
$599
MSC Cruises – MSC Divina
3.892 Reviews
Departs Feb 01, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
9-night south america cruise
Inside From
$2,096
34% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 01, 2027 from Buenos Aires, Argentina
Up to 3 deals
View Expanded Details
7-night south america cruise
Suite From
$3,509
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 01, 2027 from Camboriu
Up to 2 deals
View Expanded Details
7-night south america cruise
Inside From
$1,467
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 04, 2027 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
9-night south america cruise
Balcony From
$2,146
48% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 04, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
View Expanded Details
4-night south america cruise
Inside From
$849
MSC Cruises – MSC Divina
3.892 Reviews
Departs Feb 05, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
12-night south america cruise
Suite From
$7,200
Explora Journeys – Explora I
5.04 Reviews
Departs Feb 05, 2027 from San Juan, Puerto Rico
Up to 5 deals including Avoya Exclusives
View Expanded Details
7-night south america cruise
Inside From
$1,449
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 07, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
7-night south america cruise
Inside From
$1,449
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 08, 2027 from Camboriu
Up to 2 deals
View Expanded Details
20-night south america cruise
Inside From
$2,930
Cunard – Queen Anne
5.01 Reviews
Departs Feb 08, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including Avoya Exclusives
View Expanded Details
7-night south america cruise
Inside From
$1,106
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 10, 2027 from Maceio
Up to 3 deals
View Expanded Details
9-night south america cruise
Inside From
$2,085
33% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 10, 2027 from Buenos Aires, Argentina
Up to 3 deals
View Expanded Details
7-night south america cruise
Inside From
$1,357
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 11, 2027 from Buenos Aires, Argentina
Up to 2 deals
View Expanded Details
11-night south america cruise + tour
Suite From
$21,373
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Feb 11, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
View Expanded Details
7-night south america cruise
Inside From
$1,119
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 13, 2027 from Santos, Brazil
Up to 3 deals
View Expanded Details
9-night south america cruise
Balcony From
$1,674
55% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 13, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
View Expanded Details
7-night south america cruise
Balcony From
$1,799
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 15, 2027 from Camboriu
Up to 2 deals
View Expanded Details
7-night south america cruise
Inside From
$1,106
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 16, 2027 from Salvador, Brazil
Up to 3 deals
View Expanded Details
7-night south america cruise
Inside From
$1,119
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Feb 20, 2027 from Santos, Brazil
Up to 3 deals
View Expanded Details
7-night south america cruise
Inside From
$1,379
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 21, 2027 from Santos, Brazil
Up to 2 deals
View Expanded Details
8-night south america cruise
Balcony From
$1,681
49% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Feb 22, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
View Expanded Details
7-night south america cruise
Balcony From
$1,749
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 22, 2027 from Camboriu
Up to 2 deals
View Expanded Details
  1. 1…
  2. 16
  3. 17
  4. 18
  5. 19
  6. 20
  7. …34
South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?