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Best South America Cruises

Showing 451-475 of 827 results
7-night south america cruise
Inside From
$1,487
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 25, 2027 from Buenos Aires, Argentina
Up to 2 deals
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17-night south america cruise
Suite From
$20,599
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Feb 25, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Inside From
$949
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Feb 28, 2027 from Santos, Brazil
Up to 2 deals
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19-night south america cruise
Inside From
$1,990
Cunard – Queen Anne
5.01 Reviews
Departs Feb 28, 2027 from Santiago (Valparaiso), Chile
Up to 3 deals including Avoya Exclusives
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33-night south america cruise
Inside From
$2,700
Cunard – Queen Anne
5.01 Reviews
Departs Feb 28, 2027 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
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6-night south america cruise
Balcony From
$1,151
MSC Cruises – MSC Seaview
4.65 Reviews
Departs Mar 01, 2027 from Camboriu
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7-night south america cruise
Inside From
$1,096
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 02, 2027 from Salvador, Brazil
Up to 3 deals
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8-night south america cruise
Balcony From
$1,671
49% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Mar 02, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
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4-night south america cruise
Inside From
$609
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 04, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Inside From
$806
MSC Cruises – MSC Musica
3.54 Reviews
Departs Mar 07, 2027 from Itajai
Up to 2 deals
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3-night south america cruise
Inside From
$599
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 08, 2027 from Santos, Brazil
Up to 2 deals
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13-night south america cruise
Balcony From
$10,299
18% Off List
Viking Ocean Cruises – Viking Polaris
5.01 Reviews
Departs Mar 10, 2027 from Ushuaia, Argentina
Up to 1 deal including an Avoya Exclusive
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3-night south america cruise
Inside From
$659
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 11, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Inside From
$1,119
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 13, 2027 from Santos, Brazil
Up to 3 deals
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1-night south america cruise
Inside From
$99
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 14, 2027 from Santos, Brazil
Up to 2 deals
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3-night south america cruise
Inside From
$370
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 14, 2027 from Santos, Brazil
Up to 2 deals
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4-night south america cruise
Balcony From
$680
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 14, 2027 from Santos, Brazil
Up to 1 deal
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8-night south america cruise
Inside From
$1,985
34% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Mar 15, 2027 from Buenos Aires, Argentina
Up to 3 deals
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8-night south america cruise
Inside From
$1,750
34% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Mar 23, 2027 from Buenos Aires, Argentina
Up to 3 deals
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7-night south america cruise
Inside From
$1,079
47% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 27, 2027 from Santos, Brazil
Up to 3 deals
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4-night south america cruise
Inside From
$546
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 30, 2027 from Salvador, Brazil
Up to 2 deals
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3-night south america cruise
Balcony From
$569
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 31, 2027 from Maceio
Up to 2 deals
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1-night south america cruise
Inside From
$109
MSC Cruises – MSC Musica
3.54 Reviews
Departs Apr 01, 2027 from Santos, Brazil
Up to 2 deals
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4-night south america cruise
Inside From
$476
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Apr 03, 2027 from Santos, Brazil
Up to 2 deals
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3-night south america cruise
Inside From
$353
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Nov 24, 2027 from Santos, Brazil
Up to 1 deal
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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