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Best South America Cruises

Showing 476-500 of 827 results
3-night south america cruise
Inside From
$423
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Nov 25, 2027 from Santos, Brazil
Up to 1 deal
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3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Nov 27, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Nov 28, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Nov 29, 2027 from Camboriu
Up to 1 deal
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3-night south america cruise
Inside From
$353
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Nov 30, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$928
48% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 02, 2027 from Buenos Aires, Argentina
Up to 1 deal
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3-night south america cruise
Inside From
$353
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 03, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$829
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 04, 2027 from Santos, Brazil
Up to 1 deal
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17-night south america cruise
Suite From
$19,399
13% Off List
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Dec 04, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 05, 2027 from Santos, Brazil
Up to 1 deal
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3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 06, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 06, 2027 from Camboriu
Up to 1 deal
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4-night south america cruise
Inside From
$415
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 09, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$829
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 11, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 12, 2027 from Santos, Brazil
Up to 1 deal
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3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 13, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$889
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 13, 2027 from Camboriu
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8-night south america cruise
Inside From
$1,279
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 19, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,099
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 20, 2027 from Santos, Brazil
Up to 1 deal
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8-night south america cruise
Inside From
$1,259
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 20, 2027 from Camboriu
Up to 1 deal
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17-night south america cruise
Balcony From
$9,399
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Dec 21, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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6-night south america cruise
Inside From
$967
49% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 23, 2027 from Rio de Janeiro, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,129
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 23, 2027 from Buenos Aires, Argentina
Up to 1 deal
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7-night south america cruise
Inside From
$1,549
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 27, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,609
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 28, 2027 from Camboriu
Up to 1 deal
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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