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Best South America Cruises

Showing 501-525 of 827 results
11-night south america cruise + tour
Suite From
$22,597
Seabourn – Seabourn Venture
5.02 Reviews
Departs Dec 28, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$1,641
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Dec 29, 2027 from Rio de Janeiro, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,648
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Dec 30, 2027 from Buenos Aires, Argentina
Up to 1 deal
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6-night south america cruise
Inside From
$919
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 03, 2028 from Santos, Brazil
Up to 1 deal
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6-night south america cruise
Inside From
$969
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 04, 2028 from Camboriu
Up to 1 deal
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7-night south america cruise
Suite From
$3,670
Explora Journeys – Explora I
5.04 Reviews
Departs Jan 04, 2028 from Rio de Janeiro, Brazil
Up to 1 deal including an Avoya Exclusive
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11-night south america cruise + tour
Suite From
$21,997
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Jan 05, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$1,088
48% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 06, 2028 from Buenos Aires, Argentina
Up to 1 deal
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17-night south america cruise
Suite From
$20,999
Viking Ocean Cruises – Viking Jupiter
4.628 Reviews
Departs Jan 07, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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11-night south america cruise + tour
Suite From
$21,697
Seabourn – Seabourn Venture
5.02 Reviews
Departs Jan 07, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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82-night south america cruise
Suite From
$50,998
Seabourn – Seabourn Quest
4.644 Reviews
Departs Jan 07, 2028 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
Secret Rate
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7-night south america cruise
Inside From
$881
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Jan 08, 2028 from Paranagua, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$989
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 09, 2028 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,049
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 10, 2028 from Camboriu
Up to 1 deal
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7-night south america cruise
Inside From
$881
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Jan 11, 2028 from Rio de Janeiro, Brazil
Up to 1 deal
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8-night south america cruise
Suite From
$3,845
Explora Journeys – Explora I
5.04 Reviews
Departs Jan 11, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Inside From
$1,088
48% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 13, 2028 from Buenos Aires, Argentina
Up to 1 deal
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7-night south america cruise
Inside From
$851
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Jan 15, 2028 from Paranagua, Brazil
Up to 1 deal
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21-night south america cruise + tour
Suite From
$37,297
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Jan 15, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
View Expanded Details
7-night south america cruise
Inside From
$989
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 16, 2028 from Santos, Brazil
Up to 1 deal
View Expanded Details
7-night south america cruise
Inside From
$1,049
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 17, 2028 from Camboriu
Up to 1 deal
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13-night south america cruise + tour
Suite From
$23,497
Seabourn – Seabourn Venture
5.02 Reviews
Departs Jan 17, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Inside From
$851
50% Off List
MSC Cruises – MSC Musica
3.54 Reviews
Departs Jan 18, 2028 from Rio de Janeiro, Brazil
Up to 1 deal
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8-night south america cruise
Suite From
$4,135
Explora Journeys – Explora I
5.04 Reviews
Departs Jan 19, 2028 from Ushuaia, Argentina
Up to 1 deal including an Avoya Exclusive
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7-night south america cruise
Inside From
$978
48% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Jan 20, 2028 from Buenos Aires, Argentina
Up to 1 deal
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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