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Best South America Cruises

Showing 576-600 of 826 results
56-night south america cruise + tour
Suite From
$47,297
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 11, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Secret Rate
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67-night south america cruise + tour
Suite From
$57,597
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 11, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Secret Rate
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81-night south america cruise + tour
Suite From
$72,497
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 11, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Secret Rate
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96-night south america cruise + tour
Suite From
$88,097
Seabourn – Seabourn Venture
5.02 Reviews
Departs Mar 11, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Secret Rate
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7-night south america cruise
Inside From
$869
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 12, 2028 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$929
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 13, 2028 from Camboriu
Up to 1 deal
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7-night south america cruise
Inside From
$968
48% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 16, 2028 from Buenos Aires, Argentina
Up to 1 deal
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7-night south america cruise
Inside From
$869
49% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 19, 2028 from Santos, Brazil
Up to 1 deal
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48-night south america cruise + tour
Suite From
$33,197
Seabourn – Seabourn Pursuit
5.01 Reviews
Departs Mar 25, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Secret Rate
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4-night south america cruise
Inside From
$595
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 26, 2028 from Santos, Brazil
Up to 1 deal
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13-night south america cruise
Suite From
$29,999
Viking Ocean Cruises – Viking Polaris
5.01 Reviews
Departs Mar 26, 2028 from Ushuaia, Argentina
Up to 1 deal including an Avoya Exclusive
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3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Mar 30, 2028 from Santos, Brazil
Up to 1 deal
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4-night south america cruise
Inside From
$465
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Apr 02, 2028 from Santos, Brazil
Up to 1 deal
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3-night south america cruise
Inside From
$423
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Apr 06, 2028 from Santos, Brazil
Up to 1 deal
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19-night south america cruise
Suite From
$39,999
5% Off List
Viking Ocean Cruises – Viking Polaris
5.01 Reviews
Departs Apr 07, 2028 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Apr 09, 2028 from Santos, Brazil
Up to 1 deal
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4-night south america cruise
Inside From
$505
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Apr 12, 2028 from Santos, Brazil
Up to 1 deal
View Expanded Details
3-night south america cruise
Inside From
$393
50% Off List
MSC Cruises – MSC Meraviglia
3.889 Reviews
Departs Apr 16, 2028 from Santos, Brazil
Up to 1 deal
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17-night south america cruise
Balcony From
$8,699
Viking Ocean Cruises – Viking Star
4.440 Reviews
Departs Nov 09, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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12-night south america cruise
Balcony From
$11,499
Viking Ocean Cruises – Viking Polaris
5.01 Reviews
Departs Nov 11, 2028 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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17-night south america cruise
Balcony From
$10,499
Viking Ocean Cruises – Viking Star
4.440 Reviews
Departs Jan 16, 2029 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
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17-night south america cruise
Balcony From
$10,499
Viking Ocean Cruises – Viking Star
4.440 Reviews
Departs Feb 02, 2029 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
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15-night south america cruise
Inside From
$1,184
Carnival Cruises – Carnival Firenze
4.03 Reviews
Departs Jan 04, 2027 from Los Angeles, California
Up to 7 deals
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34-night south america cruise
Inside From
$4,669
Cunard – Queen Anne
5.01 Reviews
Departs Jan 05, 2027 from Hamburg, Germany
Up to 2 deals including an Avoya Exclusive
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29-night south america cruise
Inside From
$3,909
Cunard – Queen Anne
5.01 Reviews
Departs Jan 10, 2027 from Southampton, United Kingdom
Up to 2 deals including an Avoya Exclusive
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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