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Best South America Cruises

Showing 676-700 of 826 results
3-night south america cruise
Inside From
$599
MSC Cruises – MSC Divina
3.892 Reviews
Departs Mar 01, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Balcony From
$3,499
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Mar 06, 2027 from Barranquilla, Colombia
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8-night south america cruise
Balcony From
$1,353
56% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Mar 10, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
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7-night south america cruise
Balcony From
$4,949
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Mar 13, 2027 from Cartagena, Colombia
Up to 2 deals
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7-night south america cruise
Inside From
$1,106
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 17, 2027 from Maceio
Up to 3 deals
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7-night south america cruise
Inside From
$1,096
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 23, 2027 from Salvador, Brazil
Up to 3 deals
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7-night south america cruise
Inside From
$1,119
48% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Mar 24, 2027 from Maceio
Up to 3 deals
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7-night south america cruise
Balcony From
$4,349
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Mar 27, 2027 from Cartagena, Colombia
Up to 2 deals
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1-night south america cruise
Inside From
$89
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Apr 03, 2027 from Santos, Brazil
Up to 2 deals
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7-night south america cruise
Balcony From
$3,399
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Apr 03, 2027 from Barranquilla, Colombia
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7-night south america cruise
Inside From
$864
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 07, 2027 from Salvador, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$864
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 08, 2027 from Maceio
Up to 1 deal
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7-night south america cruise
Inside From
$864
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 14, 2027 from Salvador, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$864
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 15, 2027 from Maceio
Up to 1 deal
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8-night south america cruise
Inside From
$1,219
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 18, 2027 from Santos, Brazil
Up to 1 deal
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8-night south america cruise
Inside From
$1,264
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 21, 2027 from Salvador, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,549
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 26, 2027 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,584
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Dec 29, 2027 from Salvador, Brazil
Up to 1 deal
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6-night south america cruise
Inside From
$889
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Jan 02, 2028 from Santos, Brazil
Up to 1 deal
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6-night south america cruise
Inside From
$939
50% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Jan 05, 2028 from Salvador, Brazil
Up to 1 deal
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9-night south america cruise
Inside From
$1,300
48% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Jan 07, 2028 from Buenos Aires, Argentina
Up to 1 deal
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7-night south america cruise
Inside From
$1,029
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Jan 08, 2028 from Santos, Brazil
Up to 1 deal
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7-night south america cruise
Inside From
$1,029
49% Off List
MSC Cruises – MSC Virtuosa
5.01 Reviews
Departs Jan 15, 2028 from Santos, Brazil
Up to 1 deal
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9-night south america cruise
Inside From
$1,300
48% Off List
MSC Cruises – MSC Splendida
4.79 Reviews
Departs Jan 16, 2028 from Buenos Aires, Argentina
Up to 1 deal
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4-night south america cruise
Inside From
$519
50% Off List
MSC Cruises – MSC Divina
3.892 Reviews
Departs Jan 23, 2028 from Santos, Brazil
Up to 1 deal
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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