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Best South America Cruises

Showing 101-125 of 825 results
22-night south america cruise + tour
Inside From
$7,899
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 16, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,999
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Dec 18, 2027 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
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17-night south america cruise
Inside From
$3,949
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Dec 21, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$3,999
AmaWaterways – AmaMelodia
Departs Dec 22, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,349
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Dec 25, 2027 from Barranquilla, Colombia
Up to 2 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$3,249
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Jan 02, 2028 from San Antonio, Chile
Up to 6 deals including an Avoya Exclusive
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22-night south america cruise + tour
Inside From
$7,539
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Jan 02, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
View Expanded Details
18-night south america cruise + tour
Inside From
$4,128
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Jan 15, 2028 from Buenos Aires, Argentina
Up to 4 deals including an Avoya Exclusive
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12-night south america cruise
Suite From
$9,265
Silversea – Silver Ray
5.03 Reviews
Departs Jan 15, 2028 from Miami, Florida
Up to 4 deals including Avoya Exclusives
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15-night south america cruise
Inside From
$3,309
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Jan 17, 2028 from Buenos Aires, Argentina
Up to 6 deals including an Avoya Exclusive
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14-night south america cruise
Inside From
$5,499
50% Off List
Oceania Cruises – Sirena
4.3140 Reviews
Departs Jan 19, 2028 from Lima (Callao), Peru
Up to 4 deals including an Avoya Exclusive
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22-night south america cruise + tour
Inside From
$8,299
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Jan 19, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
View Expanded Details
17-night south america cruise
Inside From
$4,349
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Jan 24, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
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19-night south america cruise + tour
Inside From
$4,298
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Jan 29, 2028 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$3,469
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Feb 01, 2028 from San Antonio, Chile
Up to 6 deals including an Avoya Exclusive
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16-night south america cruise
Inside From
$6,599
50% Off List
Oceania Cruises – Sirena
4.3140 Reviews
Departs Feb 02, 2028 from Punta Arenas, Chile
Up to 4 deals including an Avoya Exclusive
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13-night south america cruise
Oceanview From
$4,409
44% Off
Azamara Cruises – Azamara Quest
4.6127 Reviews
Departs Feb 03, 2028 from Ushuaia, Argentina
Up to 3 deals including Avoya Exclusives
Avoya Exclusive Rate
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18-night south america cruise + tour
Inside From
$4,078
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Feb 14, 2028 from Buenos Aires, Argentina
Up to 4 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$3,259
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Feb 16, 2028 from Buenos Aires, Argentina
Up to 6 deals including an Avoya Exclusive
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12-night south america cruise
Inside From
$4,339
34% Off
Azamara Cruises – Azamara Quest
4.6127 Reviews
Departs Feb 16, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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21-night south america cruise
Inside From
$7,799
50% Off List
Oceania Cruises – Sirena
4.3140 Reviews
Departs Feb 18, 2028 from Rio de Janeiro, Brazil
Up to 4 deals including an Avoya Exclusive
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21-night south america cruise
Suite From
$24,099
58% Off List
Regent Cruises – Seven Seas Voyager
4.582 Reviews
Departs Feb 26, 2028 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
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19-night south america cruise + tour
Inside From
$4,268
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Feb 28, 2028 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
View Expanded Details
15-night south america cruise
Inside From
$3,439
Norwegian Cruise Line – Norwegian Star
4.1162 Reviews
Departs Mar 02, 2028 from San Antonio, Chile
Up to 6 deals including an Avoya Exclusive
View Expanded Details
21-night south america cruise + tour
Inside From
$6,825
Princess Cruises – Majestic Princess
4.468 Reviews
Departs Nov 30, 2028 from Lima (Callao), Peru
Up to 4 deals including an Avoya Exclusive
View Expanded Details
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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