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Best South America Cruises

Showing 151-175 of 826 results
7-night south america cruise
Balcony From
$5,098
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs May 29, 2027 from Barranquilla, Colombia
Up to 1 deal
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7-night south america cruise
Balcony From
$5,248
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Jun 26, 2027 from Barranquilla, Colombia
Up to 2 deals
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26-night south america cruise
Inside From
$3,749
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Oct 07, 2027 from Vancouver, BC, Canada
Up to 3 deals including an Avoya Exclusive
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41-night south america cruise
Inside From
$5,549
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Oct 07, 2027 from Vancouver, BC, Canada
Up to 3 deals including an Avoya Exclusive
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21-night south america cruise
Inside From
$2,954
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Oct 12, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
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36-night south america cruise
Inside From
$4,504
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Oct 12, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$2,449
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Nov 02, 2027 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$2,029
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Nov 17, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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15-night south america cruise
Inside From
$2,029
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Dec 02, 2027 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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37-night south america cruise
Inside From
$6,449
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Dec 02, 2027 from San Antonio, Chile
Up to 1 deal including an Avoya Exclusive
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22-night south america cruise
Inside From
$5,299
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Dec 17, 2027 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,679
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Jan 01, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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28-night south america cruise
Inside From
$6,679
Holland America – Zuiderdam
4.3157 Reviews
Departs Jan 06, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$5,288
AmaWaterways – AmaMagdalena
5.01 Reviews
Departs Jan 08, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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22-night south america cruise
Inside From
$5,699
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Jan 08, 2028 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$4,779
AmaWaterways – AmaMelodia
Departs Jan 12, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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14-night south america cruise
Suite From
$7,820
Silversea – Silver Shadow
4.540 Reviews
Departs Jan 15, 2028 from Cartagena, Colombia
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Balcony From
$5,788
AmaWaterways – AmaMelodia
Departs Jan 19, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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10-night south america cruise
Oceanview From
$5,169
33% Off
Azamara Cruises – Azamara Quest
4.6127 Reviews
Departs Jan 24, 2028 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
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7-night south america cruise
Balcony From
$5,578
AmaWaterways – AmaMelodia
Departs Jan 26, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
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21-night south america cruise
Suite From
$27,880
Silversea – Silver Ray
5.03 Reviews
Departs Jan 27, 2028 from Lima (Callao), Peru
Up to 3 deals including an Avoya Exclusive
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17-night south america cruise
Suite From
$13,515
Silversea – Silver Shadow
4.540 Reviews
Departs Jan 29, 2028 from Santiago (Valparaiso), Chile
Up to 3 deals including an Avoya Exclusive
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22-night south america cruise
Inside From
$5,419
Holland America – Nieuw Amsterdam
4.3198 Reviews
Departs Jan 30, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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7-night south america cruise
Suite From
$6,688
AmaWaterways – AmaMelodia
Departs Feb 02, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
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12-night south america cruise
Suite From
$13,900
Silversea – Silver Shadow
4.540 Reviews
Departs Feb 15, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
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South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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